Rohit Bhatia

ORCID: 0000-0003-4194-8749
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About
Contact & Profiles
Research Areas
  • Synthesis and biological activity
  • Analytical Chemistry and Chromatography
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Synthesis and Biological Evaluation
  • Biosensors and Analytical Detection
  • Infectious Diseases and Tuberculosis
  • Diagnosis and treatment of tuberculosis
  • SARS-CoV-2 and COVID-19 Research
  • Synthesis and Characterization of Heterocyclic Compounds
  • Long-Term Effects of COVID-19
  • Advanced biosensing and bioanalysis techniques
  • Tuberculosis Research and Epidemiology
  • Analytical chemistry methods development
  • Multicomponent Synthesis of Heterocycles
  • Metabolomics and Mass Spectrometry Studies
  • Peripheral Neuropathies and Disorders
  • Computational Drug Discovery Methods
  • Click Chemistry and Applications
  • COVID-19 Clinical Research Studies
  • Venous Thromboembolism Diagnosis and Management
  • Acute Ischemic Stroke Management
  • HER2/EGFR in Cancer Research
  • Microfluidic and Capillary Electrophoresis Applications
  • Myasthenia Gravis and Thymoma

All India Institute of Medical Sciences
2013-2025

Chitkara University
2025

Indo Soviet Friendship College of Pharmacy
2017-2024

Purdue University West Lafayette
2022

Lovely Professional University
2021

Lady Hardinge Medical College
2021

Amity University
2021

Maharaja Ranjit Singh Punjab Technical University
2018-2019

Sangath
2017-2019

Rajiv Gandhi Technical University
2019

Abstract The primary goals of green analytical chemistry (GAC) involve the development novel technologies or modification existing methods to incorporate procedures with reduced reliance on hazardous chemicals. Several approaches can be employed achieve these objectives, including utilization environmentally friendly solvents and reagents, shortening chromatographic separation times, miniaturization devices. review summarizes evolution GAC its specific principles special emphasis recent...

10.1002/sscp.202400004 article EN Separation Science Plus 2024-01-12

Abstract Solvent microextraction (SME) is designed to selectively isolate desired analytes while minimizing the presence of interfering substances in extracted sample. There are different approaches from which single‐drop (SDME) can be amalgamated with various analytical methods enhance its functionalities and improve analysis compounds like gas chromatography, liquid chromatography amplify sensitivity, selectivity, capacity detect trace amounts complex matrices. The review focuses on...

10.1002/sscp.202300243 article EN Separation Science Plus 2024-03-03

ABSTRACT The search for novel drug delivery systems has generated great interest in biopolymer‐based carriers. Among these, carboxymethyl guar gum (CMGG) been shown to be promising. CMGG is a chemically modified derivative of that synthesized by carboxymethylation with monochloroacetic acid and sodium hydroxide under optimized conditions. This improves the physicochemical properties polysaccharide, which are enhanced hydrophilicity, viscosity, swelling behavior compared unmodified Guar gum....

10.1002/pat.70119 article EN Polymers for Advanced Technologies 2025-02-01

Abstract This study explores the role of estrogen in breast cancer development through ERα and ERβ receptors highlights significance aromatase biosynthesis. Chromene-based compounds, known for their anticancer properties, were synthesized with sulfonyl substitutions to enhance efficacy. The MTT assay on MCF-7, MDA-MB-231, HCT-116 cell lines showed that (Z)-N-(3-cyano-2H-chromen-2-ylidene)benzenesulfonamide (AN1) (Z)-N-(6-bromo-3-cyano-2H-chromen-2-ylidene)methanesulfonamide (AN13) had strong...

10.1055/s-0043-1775462 article EN Synlett 2025-04-04

Cancer remains one of the most formidable global health challenges, marked by uncontrolled cell growth and division. Despite medical advancements, traditional treatments often fall short due to issues specificity, resistance, toxicity, compounded complex pathophysiology disease. In this context, natural products, particularly phytochemicals, have emerged as promising anticancer agents. Compounds such vinca alkaloids, curcuminoids, flavonoids, terpenoids, polyphenols, others demonstrated...

10.1002/cbdv.202500162 article EN Chemistry & Biodiversity 2025-04-11

A series of isatin-based fused heterocycles were designed, synthesized, and evaluated for anticancer activity against four cancer cell lines: MCF-7, MDA-MB-231, A549, HL-60. Among them, Q3 T4 found to be potent agents. Furthermore, two compounds selected epidermal growth factor receptor (EGFR) inhibitory activity. Two most EGFR inhibitors with IC50 0.22 ± 0.10 0.19 0.07 μM. The standard drug erlotinib was 0.08 0.02 Structural Activity Relationship studies showed that electronegative atoms...

10.1089/adt.2022.120 article EN Assay and Drug Development Technologies 2023-07-01
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