A5051415155- Metastasis and carcinoma case studies
- Sarcoma Diagnosis and Treatment
- Soft tissue tumor case studies
- Cutaneous Melanoma Detection and Management
- Cancer Cells and Metastasis
- Cancer Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Medical Imaging and Pathology Studies
- Breast Cancer Treatment Studies
- Congenital Diaphragmatic Hernia Studies
- Parathyroid Disorders and Treatments
- Lung Cancer Research Studies
- IL-33, ST2, and ILC Pathways
- Renal Diseases and Glomerulopathies
- Radiomics and Machine Learning in Medical Imaging
- Hepatitis Viruses Studies and Epidemiology
- Appendicitis Diagnosis and Management
- Neuroendocrine Tumor Research Advances
- Gestational Trophoblastic Disease Studies
- Intraperitoneal and Appendiceal Malignancies
- Congenital Anomalies and Fetal Surgery
- Prenatal Screening and Diagnostics
- Hidradenitis Suppurativa and Treatments
- Hepatitis C virus research
- Immunotoxicology and immune responses
University Children's Hospital, Belgrade
2025
University of Belgrade
2025
Emory University
2024
Clinical Centre of Kragujevac
2011-2023
University of Kragujevac
2011-2023
University Dermatology
2010
Galectin-3 [Gal-3] is an endogenous lectin with a broad spectrum of immunoregulatory effects: it plays important role in autoimmune/inflammatory and malignant diseases, but the precise Gal-3 pathogenesis ulcerative colitis still unknown. We used model dextran sulphate sodium [DSS]-induced acute colitis. The this disease was tested by evaluating development deficient mice administration inhibitor. Disease monitored clinical, histological, histochemical, immunophenotypic investigations....
SARS-CoV-2 continues to pose a major challenge scientists and clinicians. We examined the significance of serum concentrations vitamin D, albumin, D-dimer for severity clinical picture mortality in COVID-19. Materials methods: A total 288 patients treated COVID-19 infection participated research. The were period from May 2020 January 2021. All divided based on need oxygen therapy (Sat > 94%) into with mild or severe pictures. biochemical radiographic parameters analyzed. Appropriate...
<h2>Abstract</h2> Congenital melanoma is a very rare condition defined as recognized at or shortly after birth. It may arise de novo from transplacental metastasis of maternal melanoma. In this case report, primary congenital presented during the first four months life, and was diagnosed by histopathological, immunohistochemical, FISH genetic analysis. Re-excision sentinel lymph node biopsy performed, which revealed micrometastasis in node. No adjuvant treatment provided. There were no signs...
Interleukin-33 (IL-33)/IL-33 receptor (IL-33R, ST2) signaling pathway promotes mammary cancer growth and metastasis by inhibiting anti-tumor immunity. However, the role of IL-33/IL-33R axis in neoangiogenesis tumor necrosis is not elucidated. Therefore, aim this study was to investigate necrosis. Deletion IL-33R (ST2) gene BALB/c mice enhanced attenuated 4T1 breast model, which associated with markedly decreased expression vascular endothelial factor (VEGF) IL-33 cells. We next analyzed...
Background: COVID-19 is known to disrupt immune response and induce hyperinflammation that could potentially fatal outcome of the disease. Until now, it interplay among cytokines rather important for clinical presentation COVID-19. The aim this study was determine transcriptional activity functional phenotype T cells relationship between pro- anti-inflammatory parameters severity. Methods: All recruited patients met criteria are were divided in four groups according disease Serum levels...
The aim of this study was to detect and describe the existence incidence anatomical variations celiac trunk superior mesenteric artery. conducted on 150 persons, who underwent abdominal Multi- Detector Computer Tomography (MDCT) angiography, from April 2010 until November 2012. CT images were obtained with a 64-row MDCT scanner in order analyze vascular anatomy In our study, we found that 78% patients have classic most frequent variation origin common hepatic artery (10%). next variation,...
To establish the role of co-overexpression bcl-2 and c-myc protooncogenes in uterine cervix carcinogenesis, we examined 138 tissue samples low grade cervical squamous intraepithelial lesions (SIL), high SIL, portio vaginalis uteri (PVU) carcinoma situ PVU invasive, stage IA-IIA (study group) 36 without SIL or malignancy (control group). The expression was detected immunohistochemically using a monoclonal antibody. Fisher’s exact test (P<0.05) used to assess statistical significance....
The definition of new molecular biomarkers could provide a more reliable approach in predicting the prognosis invasive breast cancers (IBC). aim this study is to analyze expression p16 protein IBC, as well its participation malignant transformation. included 147 patients diagnosed with IBC. presence non-invasive lesions (NIL) was noted each IBC and surrounding tissue. determined by reading percentage nuclear and/or cytoplasmic epithelial cells NIL, but also stromal fibroblasts. Results...
Lung cancer is the most common cause of mortality from malignant tumors worldwide. The five-year survival rate for people with advanced stages varies considerably, 35.4% to 6.9%. angiogenic potential bcl2 not well known, nor way in which tumor cells excessive expression affect VEGF production. Hypothetically, given that growth, progression and metastasis are dependent on angiogenesis, antiapoptotic effect expected form a link between these two molecules. aim this study was evaluate...
Foreign body aspiration into tracheobronchial tree represents an urgent condition at high level of risk. Etiology is different, and this typical for all ages with highest incidence in pediatric population.A successful foreign removal (partial denture) a 34-year old man was presented. Radiography computerized tomography the chest showed localized right bronchus including middle lobe bronchus. By use rigid bronchoscopy, visualized mobilized from segmental first act, then completely...
Abstract Intussusception in adults is a very rare entity that occurs only 5% of all intestinal obstructions. Most often, 66% cases, intussusception localized to the small intestine, while jejunogastric and 0,1%. Since first case after gastrojejunostomy was described by Bozzi 1914, fewer than 200 isolated cases postoperative gastric surgery have been reported. Here we present anterograde intussusception, 15 years radical subtotal gastrectomy with Billroth II anastomosis 71-year-old man.
Dysplasia epphysealis hemimelica, also known as Trevor's disease, is an extremely rare skeletal developmental disorder of unknown etiology, characterized by osteocartilaginous outgrowth one or more epiphyses a tarsal bone during childhood.We presented sporadic case dysplasia Epipysealis hemimelica developed in the talus. A 6-year-old boy complained swelling his right ankle joint, with painful and reduced movements. Radiographies suggested excessive overgrowth dorsomedial aspect The tumor was...
Introduction. Extrapulmonary small cell carcinoma is a rare, prognostically bad tumor category. Primary, it can be localized in every organ, even the ovary, where, due to its clinical specificities, represents challenge diagnosis, as well therapy. Small ovarian (SCOC) biologically very aggressive malignant of unknown histogenesis. We presented rare case SCOC with hypercalcemia course and fatal outcome postmenopausal woman at International Federation Gynecology Obstetrics (FIGO) Ia stage....
Abstract Objectives Colorectal cancers represent the predominant malignancies affecting gastrointestinal tract. In contrast, appendiceal tumors occur less frequently. Among them, neuroendocrine (ANETs) account for approximately 50 % of cases and are often detected incidentally during unrelated procedures. Case presentation We present an extremely rare case incidental tumor appendix discovered surgery rectal adenocarcinoma provide a review relevant literature. A 70-year-old patient with...
This manuscript discusses a rare case of acute appendicitis caused by metastasis from invasive breast carcinoma no special type in 70-year-old female previously diagnosed with cancer. It delves into the diagnostic challenges and management complexities such unusual clinical presentations. The paper includes an analysis 19 documented cases, enriching understanding metastatic patterns treatment strategies underlines importance considering history malignancy when diagnosing abdominal conditions...
Abstract Several Serratia species are widely distributed in nature, but marcescens is the only frequently isolated hospitals. This pathogen mainly responsible for nosocomial infection, mostly immunocompromised hosts. A 26-year-old woman with a twin pregnancy, regularly controlled, was hospitalized at 24 + 5 weeks of gestation due to scant vaginal bleeding, lower abdominal pain, and body temperature up 37.5°C. Gynecological examination revealed bleeding accompanied by dilatation cervix. The...
Abstract In the pathology of respiratory tract, sequestration presents as a non-functional lung tissue with no communication tracheobronchial tree. It represents rare congenital bronchopulmonary and vascular malformation, which occurs at frequency 0.1 to 6%. Intralobar extralobar sequestrations are extremely anomalies, especially if they occur same time in patient. Proper diagnosis appropriate surgical therapy, absence associated provide an excellent prognosis. this paper, we describing...
Background. Giant dumbbell-shaped tumors are very rare and characterized by intra- extraspinal propagation of different dimensions. In thoracal localization, invasive growth can lead up to rib vertebra erosion. Case report. We presented a 54-year-old woman with giant dumbbell schwannoma in the posterior mediastinum. The tumor was removed approach hemilaminectomy costotransversectomy. By microscopic examination diagnosis benign made. A year after surgery, patient without neurological...
Introduction/Objective. The aim of this study was to determine the effects estrogen and progesterone receptor status on angiogenesis, proliferation, apoptosis myoma cells in premenopausal (PreM) postmenopausal (PostM) women. Methods. This a cross section; clinical-experimental, retrospective, non-interventional field fundamental pathogenesis mechanisms disease using pathohistological materials from existing archive. research included 76 patients diagnosed with uterine leiomyomas, operatively...