A5101961177- Intraperitoneal and Appendiceal Malignancies
- Metal complexes synthesis and properties
- Appendicitis Diagnosis and Management
- Pregnancy and preeclampsia studies
- Cancer and Skin Lesions
- Epilepsy research and treatment
- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
- Metastasis and carcinoma case studies
- Cancer, Hypoxia, and Metabolism
- Neuroscience and Neuropharmacology Research
- Ferrocene Chemistry and Applications
- Venous Thromboembolism Diagnosis and Management
- Protein Interaction Studies and Fluorescence Analysis
- Zoonotic diseases and public health
- Genetics and Neurodevelopmental Disorders
- Tuberous Sclerosis Complex Research
- High Altitude and Hypoxia
- Neuroendocrine Tumor Research Advances
- Diagnosis and Treatment of Venous Diseases
- SARS-CoV-2 and COVID-19 Research
- Gastrointestinal Tumor Research and Treatment
- Uterine Myomas and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Intramuscular injections and effects
Clinical Centre of Kragujevac
2019-2023
University of Kragujevac
2014-2023
BioSciCon (United States)
2012
Institut za onkologiju i radiologiju Srbije
2011
University of Pittsburgh
2005-2009
Magee-Womens Research Institute
2009
Endothelial progenitor cells (EPCs) provide paracrine support to the vascular endothelium and may also replace damaged or senescent endothelial cells. Low numbers of colony-forming units (CFU-ECs) in culture are a predictive biomarker disease. We hypothesized that number CFU-ECs derived from maternal blood decreased women with preeclampsia compared normal pregnancy.Primigravid singleton (n = 12) preeclamptic pregnancies were studied during third trimester. The assay was performed using...
The aim of this study was to determine the nasal parameters in population central Serbia and compare them with those determined earlier studies different populations. research conducted on 496 randomly selected persons (262 males 234 females), aged 18-65 years. measured were height breadth standard spreading caliper scale used for measurements. There significant differences between male female subjects. 34.72 mm females, it 36.7 mm. mean values 52.6 54.32 females males, respectively. index...
Chest X-ray has verified its role as a crucial tool in COVID-19 assessment due to practicability, especially emergency units, and Brixia score proven useful for pneumonia grading. The aim of our study was investigate correlations between main laboratory parameters, vaccination status, score, well confirm if is significant independent predictor unfavorable outcome (death) patients. designed cross-sectional multicentric study. It included patients with diagnosed infection who were...
Background/Aim. The use of cisplatin as a chemotherapeutic opened the door to new metal-based drug research. New complexes containing metals such platinum, palladium, ruthenium and gold have recently been analyzed potential antitumor agents. aim study was investigate cytotoxicity Au(III) with pincer-type ligands against cervical carcinoma cells (HeLa), breast cancer (MDA-MB-231 4T1) colon (HCT116 CT26), well examine type mechanism cell death that these induced in cells. Methods. investigated...
Intensive care units (ICUs) are expert hospital areas that provide treatment and 24 h for people who very sick. Sepsis represents a serious, severe condition it can lead to septic shock multiple organ dysfunction syndromes is one of the most common reasons patients' hospitalization in ICUs. We wanted explore prognostic values interleukin (IL) 33, soluble suppression tumorigenicity 2 (sST2), IL 27, galectin 3 critically-ill patients. assumed these parameters combination or alone could predict...
Our answer is yes, but with appropriate tools. Although preventable, cervical cancer still, second to the breast cancer, major killer of women from malignant diseases worldwide. The outreach for preventive cytological screening less than 10% in most developing counties. Screening risk factors such as HPV have contributed, still not sufficiently. At EB 2004, we presented first time our proprietary, biomarker‐based MarkPap® platform technology. biomarker cytoplasmic expression genetic changes...
Abstract Two new dinuclear Pt(II) complexes with different aromatic nitrogen‐containing heterocyclic compounds as the bridging ligands, [{Pt(en)Cl} 2 ( μ ‐1,7‐phen)](ClO 4 ) ⋅H O C1 and ‐4,7‐phen)](ClO C2 ), (1,7‐phen 4,7‐phen are 1,7‐phenanthroline 4,7‐phenanthroline while en is a bidentate coordinated ethylenediamine), were synthesized structurally characterized by NMR 1 H 13 C), IR UV‐vis spectroscopy. In vitro cytotoxic activity of these was evaluated against two tumor cell lines, human...
This manuscript discusses a rare case of acute appendicitis caused by metastasis from invasive breast carcinoma no special type in 70-year-old female previously diagnosed with cancer. It delves into the diagnostic challenges and management complexities such unusual clinical presentations. The paper includes an analysis 19 documented cases, enriching understanding metastatic patterns treatment strategies underlines importance considering history malignancy when diagnosing abdominal conditions...
Acute appendicitis in puerperium is often diagnosed too late, because clinical signs can be unrelaible. Abdominal wall rigidity rarely noticed puerpeium of weak abdominal muscles, laboratory parameters are not enough relaible and atipycal appendix presentation makes difficulties diagnosis3,4. Knowing symptoms appendicitis, possible complications their early detection, make a chance for good surgical outcome. Measuring axillar rectal temperature take confusion in, prolong time until...
Disease-specific treatments are available only for a minority of patients with genetic epilepsies, while the rest treated anticonvulsants, which ineffective in almost one-third patients.Recently approved and most effective emerging therapeutics under development treatment epilepsies overviewed after systematic search analysis relevant literature.New drugs exploit one two approaches: inhibiting hyperactive brain foci through blocking excitatory or augmenting inhibitory neurotransmission,...
Abstract Phyllodes tumors of the breast can be benign, malignant, or borderline. Benign and borderline are rare tumor types that have a positive outlook high survival rate, while risk recurrence is typical for malignant tumors. Giant phyllodes larger than 10 cm in diameter demand serious diagnostic treatment approach. In this study we present case female patient treated an exulcerated carcinoma- giant breast. The presented to department right lump with ulcerated skin nipple abnormalities....
Background and Objectives: Although vitamin D insufficiency or deficiency is prevalent in children with allergic diseases, recommendations for supplementation dosing regimens are imprecise variable the literature, because clinical trials aiming to determine optimal doses were scarce past. This study aimed investigate of D3 that may achieve therapeutically effective but not toxic serum levels a subpopulation diseases concomitant hypovitaminosis D. Materials Methods: The retrospective,...
Abstract Appendiceal mucoceles represent neoplastic and non-neoplastic, dilatated, mucus filled appendix vermiformix. Appendectomy is obligatory due to a possible malignancy. It crucially important avoid rupturing of the mucocele because it can result in pseudomyxoma peritonei, with high morbidity mortality. We presented 52-year-old man pain palpable mass lower right quadrant abdomen. The was removed without rupture, patient discharged from surgical department one day after surgery...
The habenular nuclear complex presents bilateral part of epithalamus, consisting medial (nc. habenularis medialis - MHb) and lateral lateralis LHb) nucleus. According to its anatomical position neuronal connections it is a 'crossroads' pathways the limbic system basal ganglia. human involved in control brain reward considered play very important role emotional processes. It regulation activity dopaminergic, serotonergic, noradrenergic cholinergic neurons brainstem their transmission...
Maternal leptin is elevated during pregnancy and preeclampsia, postulated to be an important mediator of reproductive function metabolic regulation. Amino acids serve as one the main nutrient sources for fetus activity placental amino acid transporters crucial in regulation fetal growth. However, role not fully understood. Objective: To investigate on system A transport human placenta. Methods: The uptake C14-MeAIB was investigated after incubation primary villous fragments isolated from...
Abstract Breast cancer is not only a mass of genetically abnormal tissue in the breast. This well-organized system complex heterogeneous tissue. Cancer cells produce regulatory signals that stimulate stromal to proliferate and migrate; then, elements respond these by releasing components necessary for tumor development provide structural support, vasculature, extracellular matrices. Developing tumors can mobilize variety cell types from both local distant niches via secret chemical factors...
Abstract Synchronous multiple carcinomas represent two or more primary carcinoma that occur sumultaneously in the same patient. In order to fulfill condition tumors are synchronous, each tumor must be and not a metastasis of another tumor. The occurrence renal synchronously with colonic is so common. On other hand, pathohistological image rare cases shows mixed glandular neuroendocrine component described earlier works. this paper, we present patient who made colonoscopy, biopsy from change...
Abstract Mucocele of the apendix is a rare clinical and pathological entity with higher incidence in female population, non-specific symptomatology that includes more diagnoses including neoplastic non-neoplastic causes dilation mucin proliferation. With obtained numerous variations symptomatology, picture, intraoperative presentation, surgical treatment histopathological findings, aim this paper an inspection into current knowledge disease, its characteristics, differential diagnosis...
Abstract Adult intussusception is a rare entity which distinct frompaediatric cases in incidence, aetiology, and management. It represents 5% of all intussusceptions the cause 1% allintestinal obstructions, 0,08% abdominal surgeries 0,003-0,02% hospital admissions. Ileocolic intussusceptionin adults unique variant nearly 100% havea malignant lead point. In our report, we described case apatient with ileocecal caused by type gastro intestinal tumor. The female patient was admitted to for...