- Sinusitis and nasal conditions
- Obstructive Sleep Apnea Research
- Nasal Surgery and Airway Studies
- Allergic Rhinitis and Sensitization
- Neuroscience of respiration and sleep
- Tracheal and airway disorders
- Head and Neck Surgical Oncology
- Asthma and respiratory diseases
- Child Nutrition and Feeding Issues
- Airway Management and Intubation Techniques
- Olfactory and Sensory Function Studies
- Delphi Technique in Research
- Research in Social Sciences
- Noise Effects and Management
- Infectious Diseases and Mycology
- Sleep and related disorders
- Dental Anxiety and Anesthesia Techniques
- Otitis Media and Relapsing Polychondritis
- Infant Development and Preterm Care
- Climate Change and Health Impacts
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Safety Warnings and Signage
- Respiratory and Cough-Related Research
- Conferences and Exhibitions Management
- Nursing Roles and Practices
Helsinki University Hospital
2016-2025
University of Helsinki
2012-2025
University of Southern Denmark
2022
Kainuun keskussairaala
1998-2021
Peijas Hospital
2005
Abstract Objectives The aim was to evaluate the predictive potential of Sinonasal Radiological (SR) and Lund‐Mackay (LM) score sinus computed tomography (CT) scans on postoperative relapses chronic rhinosinusitis (CRS). Materials Methods CRS patients ( n = 483, 12–80 years) underwent routine CT scans. SR defined by obstructed frontal recess (0 no, 1 yes) visualization middle inferior turbinate anatomy can be easily visualized, cannot visualized) each side (a total 0–6 points). Associations...
Abstract Background Sleep is important to the well‐being and development of children. Specially, small children are vulnerable effects inadequate sleep. However, not much known about frequency all types sleep problems daytime tiredness in preschool‐aged Objective To evaluate prevalence a wide spectrum problems, associations between these 3‐ 6‐year‐old Finnish Methods A population‐based study where parents ( n = 904) living Helsinki filled Disturbance Scale for Children (SDSC). Results Of...
Nasal obstruction is considered to be a potential etiological factor in sleep-disordered breathing. However, significant correlation between nasal measurements and obstructive sleep apnea has not been demonstrated so far. The aim of this study was investigate the relationships resistance, volumes selected parameters using performed both seated supine positions. We also investigated whether snoring patients our clinical sample showed increased positional or decongestive mucosal...
The first European Rhinology Research Forum organized by the for and Education in Allergy Airway Diseases (EUFOREA) was held Royal Academy of Medicine Brussels on 17th 18th November 2016, collaboration with Rhinologic Society (ERS) Global Asthma Network (GA2LEN). One hundred thirty participants (medical doctors from different specialties, researchers, as well patients industry representatives) 27 countries took part multiple perspective discussions including brainstorming sessions care...
Objective: To study emotional and behavioral problems sleep cognitive performance in snoring nonsnoring 3- to 6-year-old children. Methods: As part of an epidemiological disordered breathing (SDB) preschool-aged children, 43 snorers 46 nonsnorers participated a clinical study. Their parents completed the Child Behavior Checklist (CBCL). The children were assessed with Wechsler Preschool Primary Scale Intelligence, Revised subtests Developmental Neuropsychological Assessment (NEPSY-A)...
Abstract Objective To study the prevalence of various sleep problems at school age in a Finnish community sample and to evaluate persistence from preschool 4‐year follow‐up. Methods Parents completed Sleep Disturbance Scale for Children questionnaire on their child's during years (3–6 years) again (7–11 years). At follow‐up parents also family structure socio‐economic status. Results The 481 children questionnaires both first (girls 49%, boys 51%; mean 9, range 7–11). population level,...
The aim was to compare the control of chronic rhinosinusitis with nasal polyps (CRSwNP) after endoscopic sinus surgery (ESS), in patients with/without nonsteroidal anti-inflammatory drug exacerbated respiratory disease (NERD).Study Desing: A retrospective hospital-based sample CRSwNP NERD follow-up.Tertiary rhinology centers.Electronic patient record data from 116 (46 and 70 without NERD) undergoing ESS during 2001-17 were studied. Mean follow-up time 9.9 years (range 1.1-15.3). Endpoints...
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory disease of the nose and paranasal sinuses that significantly impactshealth-related quality life. Nonsteroidal anti-inflammatory drug (NSAID) -exacerbated respiratory (N-ERD) affects approximately one fifth CRSwNP patients. N-ERD asthma increase risk uncontrolled as measured by frequent sinus surgeries rescue treatment. Compared to non-N-ERD patients, those also have higher exacerbations, severe allergic...
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory condition affecting the passages and paranasal sinuses. It characterized by persistent inflammation often leads to considerable decline in health-related quality of life (HRQoL). A subset these patients-approximately 17.7%-have NSAID-exacerbated respiratory disease (N-ERD), more severe form that frequently necessitates repeated sinus surgeries rescue therapies. Compared individuals without N-ERD, affected patients...
Severe uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP) is a challenging condition to treat. The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 (EPOS2020) has the following criteria when considering biological therapy for severe CRSwNP: eosinophilia, need oral corticosteroids (OCS), symptom score, loss of sense smell co-morbid asthma.
Surgical treatment of nasal septal perforation remains a challenging field rhinology. A large variety techniques and grafts with promising results have been introduced for repair. However, the use fascia or periosteum has not previously evaluated sample patients.During years 2007-2014, 105 operations were performed 98 patients treated at Department Otorhinolaryngology-Head Neck Surgery, Helsinki University Hospital, Helsinki, Finland. We retrospective review closure rates complications....
Abstract Objectives The study was designed to compare upright and supine cephalometric measurements in snorers evaluate the effects of mandibular position nasal resistance on pharyngeal dimensions. Anthropometric, rhinomanometric, were used investigate predictors apnea‐hypopnea index. Study Design Prospective, cross‐sectional. Methods Forty consecutive habitually snoring men waiting for surgery (mean age, 44 y; mean body mass index, 28 kg/m 2 ) underwent an overnight polysomnographic,...
Background The aim of this study was to compare subgroups smokers and nonsmokers undergoing nasal surgery evaluate improvement stuffiness, snoring, symptoms related sleep-disordered breathing after surgery. Methods A cross-sectional prospective performed. population included 40 consecutive snoring men scheduled for surgical treatment obstruction. patients completed sleep questionnaires, an Epworth sleepiness scale, a visual analog scale intensity. They underwent polysomnography, anterior...
Upper airway side effects are common during nasal continuous positive pressure (nCPAP) treatment and may affect the use of nCPAP.It was our aim to evaluate prevalence upper symptoms in obstructive sleep apnea syndrome (OSAS) patients before nCPAP assess possible association between long-term adherence treatment.We examined 385 consecutive OSAS (79% men, mean age ± SD 52 10 years apnea-hypopnea index 33 23) by means a prospective questionnaire-based survey. The filled questionnaires about...
Forum organized by the European for Research and Education in Allergy Airway Diseases (EUFOREA) was held Royal Academy of Medicine Brussels on 17th 18th November 2016, collaboration with Rhinologic Society (ERS) Global Asthma Network (GA2LEN).One hundred thirty participants (medical doctors from different specialties, researchers, as well patients industry representatives) 27 countries took part multiple perspective discussions including brainstorming sessions care pathways research needs...
The aim was to evaluate the relative proportion of Non-steroidal anti-inflammatory drug exacerbated respiratory disease (NERD) and other comorbidities, their impact on burden outpatient visits due allergic rhinitis (AR), non-allergic (NAR), acute rhinosinusitis (ARS), chronic with nasal polyps (CRSwNP) without (CRSsNP).
Background Chronic rhinosinusitis with nasal polyposis (CRSwNP) and asthma coexist frequently share similar features of inflammation remodeling. Remodeling has become an important concept in the pathophysiology CRSwNP. It happens early development these diseases is relatively resistant to treatments. The key enzymes responsible for remodeling are matrix metalloproteinases (MMPs). In this study we examined whether CRSwNP MMP profiles. Methods Nasal secretion serum specimens controls (19...
Abstract Aim: To determine whether parent‐reported perennial rhinitis or objectively measured nasal resistance is more common in children from smoking families. assess tonsillar size, nasopharyngeal airway and upper surgery frequency with non‐smoking parents. Methods: Ninety‐five (age 3–6 years, median 68 months) participated this prospective cross‐sectional clinical study. History of symptoms was obtained, all underwent an ear–nose–throat examination, anterior rhinomanometry a lateral...
Conclusions: Upper airway symptoms were common in subjects referred for sleep study. In particular, nasal stuffiness and dryness already seemed to bother snorers before development of obstructive apnea syndrome (OSAS). Mouth increased with severity (OSA). Objectives: are patients OSAS. However, prevalence these is unknown primary snoring mild OSA. We evaluated frequency upper a large group diagnostic studies. Methods: examined 524 consecutive (69% men, mean ± SD age 51 12 years,...