Tatjana Kehler

ORCID: 0000-0003-4228-1632
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About
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Research Areas
  • Rheumatoid Arthritis Research and Therapies
  • Spondyloarthritis Studies and Treatments
  • Osteoarthritis Treatment and Mechanisms
  • Physical Education and Training Studies
  • Monoclonal and Polyclonal Antibodies Research
  • Inflammatory mediators and NSAID effects
  • Immune Response and Inflammation
  • Peptidase Inhibition and Analysis
  • Healthcare and Venom Research
  • Psoriasis: Treatment and Pathogenesis
  • Antimicrobial Peptides and Activities
  • Autoimmune and Inflammatory Disorders Research
  • Bone health and osteoporosis research
  • Musculoskeletal Disorders and Rehabilitation
  • Gout, Hyperuricemia, Uric Acid
  • Vitamin D Research Studies
  • Therapeutic Uses of Natural Elements
  • Cytokine Signaling Pathways and Interactions
  • Human Health and Disease
  • Vasculitis and related conditions
  • Pulmonary Hypertension Research and Treatments
  • Musculoskeletal pain and rehabilitation
  • Systemic Lupus Erythematosus Research
  • Myofascial pain diagnosis and treatment
  • Acute Myocardial Infarction Research

University of Rijeka
2012-2025

Institute for Medical Research and Occupational Health
2022

Institut za filozofiju
2022

University of Zagreb
2022

Opća Bolnica Zadar
2010-2021

Children's Specialized Hospital
2017

Zdravstveni centar
2012

The group of spondyloarthritis (SpA) disorders shares common clinical manifestations, including internal derangement (ID) temporomandibular joint (TMJ). This study aimed to investigate SpA activity in patients with ID TMJ. We assessed 200 neck pain using the Assessment Spondyloarthritis International Society (ASAS) criteria. TMJ was examined Diagnostic Criteria for Temporomandibular Disorders (DC/TMD protocol). Patients were divided into three groups: symptomatic TMJ, asymptomatic or healthy...

10.15644/asc59/1/1 article EN cc-by-nc-nd Acta Stomatologica Croatica 2025-03-15

Objectives Active immunization, or vaccination, with tumor necrosis factor (TNF)-Kinoid (TNF-K) is a novel approach to induce polyclonal anti-TNF antibodies in immune-mediated inflammatory diseases. This study was performed transfer the proof of concept obtained mice model rheumatoid arthritis (RA) into human. We designed pilot demonstrate feasibility therapeutic vaccination RA. Methods phase IIa, placebo-controlled, multicenter adults RA who previously experienced secondary failure TNF...

10.1371/journal.pone.0113465 article EN cc-by PLoS ONE 2014-12-17

Osteoarthritis (OA) is a chronic joint disease caused by mechanical damage and metabolic factors that support the development of low-grade inflammation. Increased levels T helper 1 pro-inflammatory cytokines in serum OA patients may granulysin (GNLY) mediated cytotoxicity, which in-turn contribute to pathogenesis OA. In present study, GNLY expression cytotoxic/apoptotic mechanisms peripheral blood were assessed. A total 40 non-obese women (median age 64 years old) with knee OA, controls 62...

10.3892/br.2022.1527 article EN Biomedical Reports 2022-03-24

Care/nursing homes globally have been severely affected by the COVID-19 pandemic and disproportionately experienced a high rate of mortality which led to introduction strict isolation policies. However, while there are studies on mortality, epidemiology, staffing challenges, mismanagement in long-term care as result COVID-19, appears be paucity information regarding Quality Life (QoL), happiness, associated well-being elderly residents these homes. Therefore, we examined if happiness level,...

10.3390/bs12110463 article EN cc-by Behavioral Sciences 2022-11-20

To compare characteristics of temporomandibular disorders (TMDs) in patients with rheumatoid arthritis (RA) to without RA.The sample included 80 (aged 33 73 years; 88% women and 22% men) 40 each group. An international diagnostic protocol for TMDs was followed.Arthralgia the most prevalent TMD RA Orofacial pain more common group than controls (42.5% vs 15%, P = .031), higher chronic grade intensity (P ≤ .005). Somatization depression were also increased < .001). In multiple logistic...

10.11607/ijp.8145 article EN The International Journal of Prosthodontics 2022-12-08

Introduction: Spondyloarthropathy is a group of different chronic rheumatic diseases. There are number physiotherapy interventions that all aim to support the trunk flexors and extensors, relieve pain, mobilize joints. The this study compare isokinetic exercises (IE) with standard exercise protocol in patients spondyloarthropathies. Methods: A total 16 subjects participated were randomly divided into two groups: (SP) other (IP). Both groups underwent same follow-up testing: Muscle strength,...

10.17532//jhsci.2024.2370 article EN cc-by Journal of Health Sciences 2024-05-15

Dipeptidyl peptidase IV (DPP IV) is a serine which has been suggested to play role in the pathogenesis of rheumatoid arthritis, but its mediator actions have not well investigated patients with spondyloarthritides.The purpose this study was investigate clinical relevance changes serum DPP activity and concentration these diseases.Serum significantly decreased spondyloarthritides arthritis compared control group, while increased.Among patients, reactive arthritis.No difference observed or...

10.5562/cca1863 article EN cc-by Croatica Chemica Acta 2012-01-01
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