A5042246149- Reproductive tract infections research
- Toxoplasma gondii Research Studies
- Microbial infections and disease research
- Gut microbiota and health
- Rabies epidemiology and control
- Herpesvirus Infections and Treatments
- Preterm Birth and Chorioamnionitis
- Macrophage Migration Inhibitory Factor
- Reproductive System and Pregnancy
University of Sassari
2013-2019
Significance Prostate cancer is the most common nonskin in America and fifth worldwide. Inflammation implicated initiation progression of prostate cancer; however, sources inflammation remain unidentified. Trichomonas vaginalis a prevalent parasite that infects epithelium associated with an increase aggressive cancer. Here, we demonstrate secreted T. protein homologous to human macrophage migration inhibitory factor elicits antibodies infected individuals, increases cell proliferation...
Objectives Trichomonas vaginalis is the causative agent of trichomoniasis, one most common sexually transmitted diseases worldwide. In recent years we have described symbiotic relationship between T and Mycoplasma hominis . How this biological association might affect pathogenicity or both microorganisms still unknown. Since local inflammation thought to play a central role in infection, investigated vitro response human macrophages naturally mycoplasma-free , as compared mycoplasma-infected...
Abstract Mycoplasma lipoproteins play a relevant role in pathogenicity and directly interact with the host immune system. Among human mycoplasmas, hominis is described as commensal bacterium that can be associated number of genital extragenital conditions. Mechanisms M. are still largely obscure, only limited proteins have been virulence. The current study focused on investigating MHO_0730 virulence factor demonstrated surface lipoprotein, potentially expressed vivo during natural infection,...
Mycoplasma hominis is considered an opportunistic pathogen able to colonize the lower urogenital tract; in females infection associated with severe pregnancy and postpartum complications, including abortion, endometritis, preterm delivery, low birth weight. Molecular mechanisms of pathogenicity virulence effectors remain poorly characterized. A number studies last decade have demonstrated that M. can establish endosymbiotic relationship Trichomonas vaginalis, a parasitic protozoon, also...