A5072678895- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Venomous Animal Envenomation and Studies
- Oral and gingival health research
- Pain Mechanisms and Treatments
- Peptidase Inhibition and Analysis
- Neuropeptides and Animal Physiology
- Circular RNAs in diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
Chinese Academy of Agricultural Sciences
2023
Abstract Background Neuropathic pain is a refractory disease and badly impacts the lives of patients. Urinary kallikrein (UK) acted as glycoprotein has been discovered to play pivotal role in neuroprotection. However, regulatory correlative pathways UK progression neuropathic remain dimness. Methods The chronic constriction injury (CCI) rat model was firstly established mimic pain. withdrawal threshold measured through Von Frey test. levels TNF-α, IL-1β IL-6 were determined ELISA. ROS, GSH,...
Sexual maturation heterosis has been widely exploited in animal crossbreeding. However, the underlying mechanism rarely explored chicken. In present study, we performed reciprocal crossing between White Leghorn and Beijing You chicken to evaluate phenotypes related sexual maturation, profiled ovary circRNAs of purebreds (WW, YY) crossbreds (WY, YW) elucidate molecular for maturation. Pubic space oviduct length exhibited positive heterosis, age at first egg (AFE) negative crossbreds. We...
Crossed beak is a complex mode of inheritance with prevalence ranging from 0.2% to 7.4% in at least 12 chicken strains worldwide. To reveal the intrinsic factors causing crossed beaks, genes expression patterns bilateral mandibular condyle between affected and normal birds were characterized by RNA sequencing analysis present studies. was induced short length unilateral ramus, total 110 differentially expressed up- or down-regulated (short) side as compared side. Carbonic anhydrase 2 (CA2)...