A5016791680- Immunotherapy and Immune Responses
- Neurofibromatosis and Schwannoma Cases
- Management of metastatic bone disease
- Spinal Fractures and Fixation Techniques
- Meningioma and schwannoma management
- Immune Cell Function and Interaction
- Cancer Immunotherapy and Biomarkers
- Immune Response and Inflammation
- Bone Tumor Diagnosis and Treatments
- Glioma Diagnosis and Treatment
- Nanoplatforms for cancer theranostics
- Cancer, Hypoxia, and Metabolism
- Pelvic and Acetabular Injuries
- Cancer Research and Treatments
- Trigeminal Neuralgia and Treatments
- Medical Imaging and Analysis
- T-cell and B-cell Immunology
- Cervical and Thoracic Myelopathy
- Photodynamic Therapy Research Studies
- RNA Interference and Gene Delivery
Novosibirsk Scientific Research Institute of Traumatology and Orthopedics. Ya.L. Tsivyan
2013-2023
Federal Agency for Health and Social Development
2007
Dumb-bell schwannomas (neurinomas) account for 15 % of the total number spinal neurinomas. Their surgical removal in cervical spine is a technical challenge due to intricate anatomical relationships. The paper presents clinical case recurrence dumb-bell neurinoma at cervicothoracic level 20 years after its single-stage removal. tumor was confirmed by data neuroimaging monitoring. Repeated performed. describes details course disease, and radiological manifestations, results neurophysiological
In present work, a comparative analysis of cytostatic and cytotoxic activity IL-4 IFNα-induced dendritic cells (IL-4- IFN-DCs) has been performed in healthy donors patients with brain tumors. Cytostatic was evaluated, as capacity DCs to inhibit growth NK-resistant HEp-2 A-549 tumor cell lines, whereas measured by assessment lysis. As compared IL4-DC, IFN-DCs from displayed more pronounced effect similar against cells. the tumors, were characterized decreased activity. Meanwhile, malignant...
The article describes the treatment of a 20-year-old patient with spinal hourglass schwannoma (neurinoma) in thoracic spine, growing from right Th3 root, spreading into cavity and compressing apex lung. introduction presents frequency occurrence such neoplasms among all cord tumors. Complaints, neurological symptoms, neoplasm diagnosis methods its clinical radiological manifestations are presented. stages techniques total surgical removal through posterior paravertebral minimally invasive...
Objective. To analyze long-term clinical results of using neodymium laser for surgical treatment patients with spinal dumbbell-shaped tumors. Materials and Methods. Clinical material is based on in 83 (49 females 34 males) The were divided into two groups depending the tumor resection technology: 57 (control group) operated conventional neurosurgical technique, 26 (study - radiation a wavelength 1.064 mkm. Results. In study group good achieved 10 (38.5 %), satisfactory 12 (46.1 poor 4 (15.4...
The problem of search and development new approaches to integrated treatment patients with malignant brain glioma remain one the most urgent issues for contemporary neurosurgery neurooncology. In spite applied efforts results a complex therapy glioma, especially glioblastoma, are utterly unsatisfactory. Immunotherapy is directions searching generation cytotoxic cells able lyse tumor. Combination various immunotherapeutic regarded perspective way. Since 1999 Neurosurgical Clinic Novosibirsk...
The Problem of basal meningioma's surgical removal hasn't yet been solved and still is great importance due to the development intra- postoperative complications their frequent recurrence. All these factors influence quality patient's life. In current study frequency recurrence continued growth tumors were analyzed, as well life 83 patients operated on for meningiomas in Novosibirsk Institute Traumatology Orthopedics from 1995 2008. Of 51 neodymium laser was used during removal. 32 cases,...
Objective. To study the long-term results of surgical treatment intramedullary ependymomas. Material and Methods . Spinal ependymomas were detected in 91 (20.2 %) cases a total number operated patients. Intramedullary location tumor was diagnosed 41 (45.0 Ependymoma benign 78.1 % anaplastic 9 (21.9 %). Radical removal achieved 36 (87.8 patients, subtotal resection performed 5 (12.2 Results Gross neurological symptoms persisted period 6 (24.0 Structural changes spine associated with...
The aim. To analyze the results of surgical treatment sacral schwannomas with their extension into lower pelvis. Materials and methods . We analyzed clinical 25 patients schwannomas, including those ventral growth pelvic cavity. All were operated at Clinic Neurosurgery Novosibirsk Research Institute Traumatology Orthopedics named after Ya.L. Tsivyan for a 10-year period. analysis literature describing prevalence, classification, diagnosis tumors in particular was carried out. features...
The paper describes clinical features, diagnosis and treatment of spinal cord tumor localized in the anterior portion craniovertebral junction a 43-years-old patient after course stereotactic radiotherapy with CyberKnife linear accelerator. surgical included microsurgical total removal intradural extramedullary at level through far lateral approach neurophysiologic monitoring. Good results achieved early postoperative period were presented by restoration muscle force limbs (regression...
РЕЗУЛЬТАТЫ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ МЕНИНГИОМ ЗАДНЕЙ ПОВЕРХНОСТИ ПИРАМИДЫ ВИСОЧНОЙ КОСТИ (АНАЛИЗ МОНОЦЕНТРОВОЙ КОГОРТЫ) Васильев И.А. 1 , Ступак В.В. Цветовский С.Б. Пендюрин И.В. Лебедев А.К. Бузунов А.В. monitoring and adequate patient positioning provide the required conditions for good post-op outcome with low complication rates, comparable to literature data.
The purpose of this study was to develop methods brain tumor PDT, based on locoregional injection photosensitive substance in liquor system. first experience performing PDT procedure showed that it is well endured by patients with tumors. MRI and clinical examinations 14 months after revealed the absence continued growth. All testifies favourable preconditions for further development application treatment technique neurooncology.