Jolanta Liesienė

ORCID: 0000-0003-4279-7460
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Research Areas
  • Bone Tissue Engineering Materials
  • Protein purification and stability
  • Analytical Chemistry and Chromatography
  • Electrospun Nanofibers in Biomedical Applications
  • biodegradable polymer synthesis and properties
  • Glycosylation and Glycoproteins Research
  • Advanced Cellulose Research Studies
  • Advanced Drug Delivery Systems
  • Enzyme Production and Characterization
  • Enzyme Catalysis and Immobilization
  • Drug Solubulity and Delivery Systems
  • Monoclonal and Polyclonal Antibodies Research
  • Dental materials and restorations
  • Synthesis and properties of polymers
  • Microbial Metabolism and Applications
  • Food composition and properties
  • Enzyme-mediated dye degradation
  • Microfluidic and Capillary Electrophoresis Applications
  • Wound Healing and Treatments
  • Electrochemical sensors and biosensors
  • Polysaccharides Composition and Applications
  • Periodontal Regeneration and Treatments
  • Competency Development and Evaluation
  • Biochemical Analysis and Sensing Techniques
  • Proteins in Food Systems

Kaunas University of Technology
2009-2019

Kaunas University of Applied Engineering Sciences
1992

The aim of this study is to investigate the biomimetic mineralization on a cellulose-based porous matrix with an improved biological profile. cellulose was precalcified using three methods: (i) samples were treated solution calcium chloride and diammonium hydrogen phosphate; (ii) carboxymethylated stored in saturated hydroxide solution; (iii) mixed silicate order introduce silanol groups combine them ions. All methods resulted surfaces after immersion simulated body fluid solution. Over...

10.1155/2013/452750 article EN cc-by BioMed Research International 2013-01-01

Cellulose scaffolds containing nano- or micro-hydroxyapatite (nHA μHA) were prepared by the regeneration of cellulose from its acetylated derivative and mechanical immobilization inorganic particles, followed freeze-drying. Microtomographic (micro-computed tomography) evaluation revealed that both presented a highly interconnected porous structure, with mean pore diameter 490 ± 94 540 132 μm for cellulose/nHA cellulose/μHA, respectively. In vitro in vivo characterizations developed...

10.1002/term.2651 article EN Journal of Tissue Engineering and Regenerative Medicine 2018-03-02

Hydroxylation of L-tyrosine to 3,4-dihydroxyphenylalanine (L-DOPA) by immobilized tyrosinase in the presence ascorbic acid (AH2), which reduces DOPA-quinone L-DOPA, is characterized low reaction yields that are mainly caused suicide inactivation L-DOPA and AH2. The main aim this work was compare processes with native identify conditions limit produce substrate conversions above 50% using HPLC analysis. It shown does not suffer from partitioning diffusion effects, allowing a direct comparison...

10.1371/journal.pone.0164213 article EN cc-by PLoS ONE 2016-10-06

Recently, usage of marine-derived materials in biomedical field has come into prominence due to their promising characteristics such as biocompatibility, low immunogenicity and wide accessibility. Among these marine sources, cuttlebone been used a valuable component with its trace elemental composition traditional medicine. Recent studies have focused on the use bioactive agent for tissue engineering applications. In this study, hydroxyapatite particles were obtained by hydrothermal...

10.1177/0885328218811040 article EN Journal of Biomaterials Applications 2018-11-19

In bioprocesses lipases are typically used in immobilized form, irrespective of type reaction systems, to ensure an even distribution catalysts water restricted media and/or facilitate separation and reuse. these studies we report on the selection appropriate enzyme-carrier preparation for hydrolysis aqueous biphasic systems transesterification organic solvent. For this Candida rugosa lipase was bound by adsorption or covalent attachment onto various carriers give 24 preparations. Selection...

10.18388/abp.2014_1914 article EN cc-by Acta Biochimica Polonica 2014-03-17

Abstract The hydrophobic packing for preparative low pressure interaction chromatography (HIC) on the new granulated cellulose matrix Granocel were prepared by alkylation with phenyl glycidyl ether in presence of sodium hydroxide. ligand concentration up to 600 μmol/g was achieved high reproducibility. relative amount eluted model protein at fixed set conditions used as a criterion evaluation hydrophobicity adsorbents. found depend accessible, rather than total, coupled well nature matrix....

10.1080/10826079408013366 article EN Journal of Liquid Chromatography 1994-02-01
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