A5006464205- Cardiac, Anesthesia and Surgical Outcomes
- Hepatitis B Virus Studies
- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Environmental DNA in Biodiversity Studies
- Protist diversity and phylogeny
- Cervical Cancer and HPV Research
- Anesthesia and Pain Management
- Microbial Community Ecology and Physiology
- Advanced Breast Cancer Therapies
- Genital Health and Disease
- Air Quality and Health Impacts
- Airway Management and Intubation Techniques
- Sepsis Diagnosis and Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrest and Resuscitation
- Vibrio bacteria research studies
- Coronary Interventions and Diagnostics
- Oral health in cancer treatment
- Polymer Science and PVC
- Metastasis and carcinoma case studies
- Hereditary Neurological Disorders
International Vaccine Institute
2022-2024
Yonsei University
2015-2020
American College of Gastroenterology
2020
Gangnam Severance Hospital
2018
Inje University
2010-2017
Creative Commons
2015-2017
Objective: We investigated microsatellite instability (MSI) status and programed cell death ligand 1 (PD-L1) expression as predictors of prognosis responsiveness to chemotherapy for stage II/III gastric cancer. Background: The clinical implications MSI PD-L1 in cancer have not been well-elucidated. Methods: Tumor specimens information were collected from patients enrolled the CLASSIC trial—a randomized controlled study capecitabine plus oxaliplatin-based adjuvant chemotherapy. Five...
In October, 2017, WHO launched a strategy to eliminate cholera by 2030. A primary challenge in meeting this goal is the limited global supply capacity of oral vaccine and worsening outbreaks since 2021. To help address current shortage vaccine, prequalified Euvichol-Plus was reformulated reducing number components inactivation methods. We aimed evaluate immunogenicity safety Euvichol-S (EuBiologics, Seoul, South Korea) compared with an active control Shanchol (Sanofi Healthcare India,...
BackgroundAlthough eastern Asian countries are exposed to high levels of air pollution, the impact long-term exposures fine particulate matter (PM2.5) pollution on all-cause and cardiovascular mortality is not well identified. We assessed relationship between PM2.5 exposure all-cause/cardiovascular mortalities.MethodsWe included 436,933 subjects who received national health examinations from Korean National Health Insurance Service-based Sample Cohort. matched subjects’ residential-address...
Although studies regarding dental developmental disturbances after childhood cancer treatment have increased, they many limitations. Studies analyzing the significance of independent clinical risk factors with regard to health status are also rare. We aimed investigate for disturbances, particularly severe in survivors (CCS).
Purpose To develop a system for assessment of tumor regression grade (TRG) with magnetic resonance (MR) imaging that is applicable to rectal mucinous adenocarcinoma (RMAC) and obtain preliminary evaluation the association MR TRG response preoperative concurrent chemotherapy radiation therapy (CCRT). Materials Methods This retrospective study was approved by institutional review board, informed consent waived. Pre- post-CCRT images 59 patients RMAC (median age, years; range, 29-80 42 men...
Abstract Background and Aims Hepatocellular carcinoma (HCC) risk in chronic hepatitis B (CHB) substantially decreased the era of potent antiviral therapy. We developed an optimized HCC prediction model for CHB with well‐controlled viremia by nucelos(t)ide analogs (NUCs). Method analysed those who achieved virological response (VR; serum HBV‐DNA < 2000 IU/mL on two consecutive assessments) NUCs. Liver stiffness transient elastography, ultrasonography laboratory tests was performed at time...
In this retrospective analysis of 10,575 patients who used fentanyl-based intravenous patient-controlled analgesia (IV-PCA) after surgery, we evaluated difference between young and elderly on their characteristic adverse effects.We reviewed the data collected from were provided IV-PCA for pain control following elective surgery under either general or spinal anesthesia September 2010 March 2014. Postoperative pain, incidence PCA-related effects, risk factors need rescue analgesics...
There has been a rising interest in the possible association between perioperative opioid use and postoperative outcomes cancer patients. Continuous surgical wound infiltration with local anesthetics is nonopioid analgesic technique that can be used as pain management alternative to opioid-based intravenous patient-controlled analgesia (IV PCA). The aim of this study was compare effects an regimen versus anesthetic infiltration-based on immune modulation short-term recurrence or metastasis...
Abstract Background and Aim Recently, the application of hemostatic powder to bleeding site has been used treat active upper gastrointestinal (UGIB). We aimed assess effectiveness polysaccharide (PHP) in patients with non‐variceal UGIB. Methods reviewed prospectively collected 40 UGIB treated PHP therapy between April 2016 January 2017 (PHP group) 303 conventional 2012 October 2014 (conventional group). compared rate successful hemostasis rebleeding two groups after as well before propensity...
OBJECTIVES: Nucleos(t)ide analogues (NUCs) are not routinely recommended for patients with hepatitis B e antigen–positive chronic virus (HBV) infection who have persistently elevated serum HBV DNA level (>20,000 IU/mL) but normal alanine aminotransferase (<40 IU/L) level. Here, we evaluated the cumulative risks of hepatocellular carcinoma (HCC) in such (the untreated [pEDNA] group) compared inactive carriers IC group). METHODS: Patients pEDNA (n = 126) and 621) were enrolled between...
// Kun Yang 1, 2, 3, 4, * , Yoon Young Choi Wei-Han Zhang 2 Xin-Zu Chen Mi Kyung Song 5 Jinae Lee Bo 1 Zhi-Xin Hyoung-Il Kim 4 Jia-Ping Jae-Ho Cheong 3 Zong-Guang Zhou Woo Jin Hyung Jian-Kun Hu Sung Hoon Noh Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, Laboratory Gastric Cancer, State Key Biotherapy, Severance Yonsei University Health System, College Medicine, Seoul, Republic Korea Robot and Minimal Invasive Surgery Center, Biostatistics...
Postoperative management after major lung surgery is critical. This study evaluates risk factors for predicting mandatory intensive care unit (ICU) admission immediately resection. We retrospectively reviewed patients whom the surgeon requested an ICU bed before resection surgery. Patients were classified into three groups. Univariable and multivariable logistic regression analyses performed, a clinical nomogram was constructed. Among 340 patients, 269, 50, 21 no need ICU, admission,...
Descent of the uterus is a major etiology uterine prolapse. However, true cervical elongation can cause prolapse without descent. The aim study was to investigate clinical outcomes Manchester operation in patients with caused by "true elongation," compared vaginal hysterectomy (VH). Medical records who underwent or VH from 2006 2015 were reviewed. True defined on basis C point Pelvic Organ Prolapse Quantification (POP-Q) system ≥0 and D ≤-4, as well estimated length ≥5 cm. primary outcome...
Aims: To evaluate the differences and changes of testicular volume elasticity in normal (NL) testes undescended (UDTs) children using shear wave elastography (SWE).Materials methods: Testicular ultrasound images from younger than 60 months old were retrospectively reviewed. volumes elasticities compared between UDT group NL group. In patients with unilateral (uUDT), we also values uUDT contralateral grossly (CGN) testis groups.Results: There 25 UDTs including 4 bilateral groupand 54 While...
We evaluated the combined effects of vitamin D and daily calcium intake on bone mineral density (BMD) osteoporosis in Korean postmenopausal women.This study is a cross-sectional consisting 1,921 women aged 45 to 70 years without thyroid dysfunction, from 2008-2011 National Health Nutrition Examination Survey. Participants were classified into six groups according serum 25-hydroxyvitamin (25(OH)D) levels intake. BMD was measured using dual-energy X-ray absorptiometry at femur lumbar spine, by...
Abstract We investigated the potential application of preoperative serum metabolomes in predicting recurrence patients with resected pancreatic cancer. From November 2012 to June 2014, who underwent potentially curative pancreatectomy for ductal adenocarcinoma were examined. Among 57 patients, 32 men; 42 had head cancers. The could be clearly categorized into two main clusters using 178 metabolomes. Patients within cluster 2 showed earlier tumor recurrence, compared those 1 (p = 0.034). A...
Prognostic nutritional index (PNI) reflects the and immunologic status of patients. The clinical application PNI is already well-known in various kinds solid tumors. However, there no study investigating relationship between oncological outcome resected ampulla Vater (AoV) cancer.From January 2005 to December 2012, medical records patients who underwent pancreaticoduodenectomy for pathologically confirmed AoV cancer were retrospectively reviewed. Long-term outcomes compared according...