A5018650275- Systemic Lupus Erythematosus Research
- Monoclonal and Polyclonal Antibodies Research
- Cytomegalovirus and herpesvirus research
- Atherosclerosis and Cardiovascular Diseases
- Polyomavirus and related diseases
- Immunodeficiency and Autoimmune Disorders
- Prostate Cancer Treatment and Research
- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Biochemical and Molecular Research
- Genetic factors in colorectal cancer
- Prostate Cancer Diagnosis and Treatment
- Protein Tyrosine Phosphatases
- Cell death mechanisms and regulation
- Phagocytosis and Immune Regulation
- Cytokine Signaling Pathways and Interactions
- Neurological Complications and Syndromes
- Cell Adhesion Molecules Research
- Urologic and reproductive health conditions
West China Hospital of Sichuan University
2019-2025
Sichuan University
2019-2025
Case presentationIn the context of solid organ transplantation (SOT), patients are routinely administered immunosuppressive agents, rendering them highly vulnerable to opportunistic infections, particularly during initial 1-12 month post-procedure.These infections often attributed a diverse array pathogens, encompassing viruses, fungi, parasites, and bacteria 1 .Among myriad complications that can arise, respiratory sepsis most frequently encountered, whereas central nervous system (CNS)...
The study aimed to retrospectively investigate the clinical significance of anti-rods and rings (anti-RR) antibodies in antinuclear (ANAs) test samples western China. Between January 2016 November 2018, laboratory data details patients with positive anti-RR were collected analysed. results showed that total 197 227 tested, 109 453 presented ANAs (55.50%), but only 107 (0.10%), including 51 females 56 males. Diagnose established patients: 25 hepatopathy (HCV 8/25, HBV 12/25); 13 autoimmune...
The goal of this study was to investigate the clinical application free/total prostate-specific antigen (F/T PSA) ratio, considering new broad serum total PSA (T-PSA) "gray zone" 2.0-25.0 ng ml-1 in differential diagnosis prostate cancer (PCa) and benign diseases (BPD) men over 50 years Western China. A 1655 patients were included, 528 with PCa 1127 BPD. Serum T-PSA, free (F-PSA), F/T ratio analyzed. Receiver operating characteristic curves used assess efficiency ratio. There 47.4% T-PSA...
To reveal the relationship between anti-Golgi antibody (AGA) and clinical diseases through retrospective analysis.The data of 584 cases testing positive for AGA in past 11 years were collected retrospectively analyzed.AGA pattern accounted .2% ANA results. In total, 35.0% diagnosed patients had autoimmune (AID), mainly rheumatoid arthritis (RA). High-titer (≧1:1000) was common AID. nondiagnosed with symptoms, joint pain/muscle pain most common.Positive high titer closely related to RA. Joint...
Defects in apoptotic cell clearance is a pathogenic factor systemic lupus erythematosus (SLE). This study screened potential single nucleotide polymorphisms (SNPs) related to anti-apoptosis from an SLE family and explored their contribution susceptibility Chinese women.Four SNPs (IKBKE rs15672, BANK1 rs12640056, rs6842661, NFKBIA rs1957106) with were analyzed for clinical characteristics between 567 patients 345 healthy control subjects.IKBKE rs15672 G/A rs12640056C/T associated (rs15672 A...
Abstract In this study, we aimed to investigate the relationship of IKBKE rs15672 and BANK1 rs12640056 gene polymorphisms with systemic lupus erythematosus (SLE) susceptibility in China. A case-control study was performed on 567 SLE patients 345 healthy controls. Six single nucleotide (rs15672, rs2296164, rs12640056, rs6842661, rs1957106 rs2274064) clinical features were analyzed. Genotyping executed improved multiplex ligation detection reaction assay. SNP increased risk ( P = 0.028, OR...