Shiuan‐Chih Chen

ORCID: 0000-0003-4301-0340
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About
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Research Areas
  • Streptococcal Infections and Treatments
  • Hepatitis B Virus Studies
  • Vibrio bacteria research studies
  • Antimicrobial Resistance in Staphylococcus
  • Long-Term Effects of COVID-19
  • Amoebic Infections and Treatments
  • Health Systems, Economic Evaluations, Quality of Life
  • COVID-19 Clinical Research Studies
  • Pneumonia and Respiratory Infections
  • Pharmaceutical Practices and Patient Outcomes
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Viral gastroenteritis research and epidemiology
  • Diet and metabolism studies
  • Liver Disease Diagnosis and Treatment
  • Hepatitis Viruses Studies and Epidemiology
  • Protease and Inhibitor Mechanisms
  • Gallbladder and Bile Duct Disorders
  • Adipose Tissue and Metabolism
  • Alcohol Consumption and Health Effects
  • Appendicitis Diagnosis and Management
  • Bacterial Identification and Susceptibility Testing
  • Mycobacterium research and diagnosis
  • Acute Ischemic Stroke Management
  • TGF-β signaling in diseases
  • Muscle metabolism and nutrition

Chung Shan Medical University Hospital
2015-2024

Chung Shan Medical University
2013-2024

Bridge University
2012

BACKGROUND The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score has been verified as a useful diagnostic tool detecting necrotizing fasciitis (NF). Its application, however, is mainly NF types I and II. practical relevance of the LRINEC Vibro vulnificus–related skin soft tissue infection (SSTI) was hardly ever investigated. aim this study to assess applicability scoring system identify NF-predicting factors in patients with V. vulnificus–caused SSTI. METHODS A retrospective...

10.1097/ta.0b013e318270d761 article EN Journal of Trauma and Acute Care Surgery 2012-11-27

Mitochondria are highly dynamic organelles, balancing synthesis and degradation in response to increases mitochondrial turnover (i.e., biogenesis, fusion, fission, mitophagy) function. The aim of this study was investigate the role polyphenols regulation functions dynamics C2C12 myotubes their molecular mechanisms. Our results indicate that gallic acid rutin most potential polyphenol compounds 15 phenolic acids 5 flavonoids. Gallic were associated with a significantly greater DNA (cytochrome...

10.3390/antiox10020286 article EN cc-by Antioxidants 2021-02-13

Vibrio vulnificus infection is uncommon but potentially life-threatening. The aim of this study was to evaluate clinical outcomes and prognostic factors for patients with V. infections admitted an intensive care unit.Retrospective study.Multidisciplinary unit in a 2300-bed teaching hospital.Eighty-five adult (≥ 18 yrs) who required were enrolled reviewed during 10-yr period.None.Thirty-four the 85 died, giving mortality rate 40%. mean Acute Physiology Chronic Health Evaluation II score on...

10.1097/ccm.0b013e3181eeda2c article EN Critical Care Medicine 2010-07-23

To date, no study associated the genetic polymorphisms of high-mobility group box 1 protein (HMGB1) with development uterine cervical cancer. We therefore conducted this to investigate associations HMGB1 single-nucleotide (SNPs) carcinogenesis and clinicopathological characteristics cancer patients. Five hundred two women, including 112 invasive cancer, 85 precancerous lesions cervix, 305 normal controls, were consecutively enrolled into study. Analysis SNPs was done by real-time polymerase...

10.1007/s13277-016-5408-0 article EN Tumor Biology 2016-10-04

Urothelial cell carcinoma (UCC) is one of the major malignancies genitourinary tract, and it induced by carcinogenic epidemiological risk factors. H19 most crucial long noncoding RNAs (lncRNAs) involved in various types bladder cancer. In this study, we examined single-nucleotide polymorphisms (SNPs) to investigate UCC susceptibility clinicopathological characteristics. Using real-time polymerase chain reaction, analyzed five SNPs 431 patients controls without The results showed that with...

10.3390/ijerph16081322 article EN International Journal of Environmental Research and Public Health 2019-04-12

Abstract Human papillomavirus (HPV) infection is associated with cancer and can be prevented through vaccination. Few studies from Taiwan have reported on HPV among human immunodeficiency virus (HIV)-infected subjects. The aim of this study was to examine the prevalence men who sex (MSM) without HIV in Taiwan, explore behavioral risk factors thereof. We conducted a cross-sectional during 2013 2016 collect data MSM aged 20 years or older. used questionnaire face-to-face interview,...

10.1097/md.0000000000013201 article EN cc-by-nc Medicine 2018-11-01

Journal Article Corrected proof Impact of prehospital care and door-to-computed tomography scan time on stroke outcomes Get access Kai-Lun Sheu, Sheu Conceptualization, Investigation, Methodology, Validation, Writing - original draft, review & editing Institute Medicine, Chung Shan Medical University, Taichung, TaiwanSchool TaiwanDepartment Family Community University Hospital, Taiwan Search for other works by this author on: Oxford Academic PubMed Google Scholar Shiuan-Chih Chen, Chen...

10.1093/qjmed/hcae002 article EN QJM 2024-01-16

Abstract Background: Helicobacter pylori are associated with chronic antral gastritis that is related to duodenal ulcer, gastric and probably adenocarcinoma. Infection of H. during childhood considered an important risk factor for carcinoma in adult life. Materials Methods: To examine the epidemiologic characteristics infection among schoolchildren central Taiwan, a community‐based survey was carried out using stratified sampling 10 elementary schools three junior high including students...

10.1111/j.1523-5378.2007.00496.x article EN Helicobacter 2007-05-04

Introduction: Vibrio vulnificus infection, an uncommon but life-threatening illness, manifests as two main types, primary septicemia and wound infections. Little information regarding the seasonality of V. infections in tropical areas prognostic factors is available. Methodology: This retrospective study was conducted to include 159 vulnificus-infected admissions at our institution southern Taiwan, 63 with (Group 1) 96 2), from 1999 2008, for analysis. Results: The case-fatality rate 24%....

10.3855/jidc.3008 article EN cc-by The Journal of Infection in Developing Countries 2013-07-15

Obesity is defined as a condition of excessive fat tissue accumulation. It was the major factor most closely associated with lifestyle-related diseases. In present study, we investigated effect astaxanthin on inhibition lipid accumulation in 3T3-L1 adipocytes. adipocytes were treated 0–25 µg/mL for 0–48 h. The result indicated that significantly decreased oil Red O stained material (OROSM), intracellular triglyceride accumulation, and glycerol 3-phosphate dehydrogenase (GPDH) activity (p...

10.3390/molecules25163598 article EN cc-by Molecules 2020-08-07
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