A5045621283- Gout, Hyperuricemia, Uric Acid
- Vitamin D Research Studies
- Urticaria and Related Conditions
- Case Reports on Hematomas
- Bone health and osteoporosis research
- Spondyloarthritis Studies and Treatments
- Pharmacological Effects and Toxicity Studies
- Bone and Joint Diseases
- Connective tissue disorders research
- Eosinophilic Disorders and Syndromes
- Muscle and Compartmental Disorders
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Alcohol Consumption and Health Effects
- Musculoskeletal Disorders and Rehabilitation
- Thyroid Disorders and Treatments
- Inflammasome and immune disorders
- Parathyroid Disorders and Treatments
- Medical and Biological Sciences
- Musculoskeletal synovial abnormalities and treatments
- Rheumatoid Arthritis Research and Therapies
Faes Farma (Spain)
2020
University of the Basque Country
2018-2020
Hospital de Cruces
2014-2018
Center for Rheumatology
2018
BioCruces Health research Institute
2018
ABSTRACT Vitamin D has shown to play a role in multiple diseases due its skeletal and extraskeletal actions. Furthermore, vitamin deficiency become worldwide health issue. Few supplementation guidelines mention calcifediol treatment, despite being the direct precursor of calcitriol biomarker status. This 1-year, phase III–IV, double-blind, randomized, controlled, multicenter clinical trial assessed efficacy safety 0.266 mg soft capsules D–deficient postmenopausal women, compared...
To examine the predictive validity of Gout Activity Score (GAS), its correlation with Impact Scale (GIS) and their sensitivity to change.
ABSTRACT Vitamin D plays a major role in bone health and probably also multiple extraskeletal acute chronic diseases. Although supplementation with calcifediol, vitamin metabolite, has demonstrated efficacy safety short-term clinical trials, its effects after long-term monthly administration have been studied less extensively. This report describes the results of 1-year, phase III-IV, double-blind, randomized, controlled, parallel, multicenter superiority trial to assess calcifediol 0.266 mg...
Background: Vitamin D deficiency is a highly prevalent entity worldwide, with relevance in specific diseases and stages of life 1 . Few guidelines assess the indications optimal dosing general population, although there no international consensus, 800IU/day associated benefits bone metabolism. Calcifediol, vitamin analog, presented as therapeutic alternative. Objectives: To efficacy calcifediol treatment deficiency, compared recommendations for cholecalciferol postmenopausal women. Methods:...
<h3>Background</h3> development of tophi has been associated with increasing level serum urate (Gutman AB, A&R 1973), whereas other factors have not clearly stated, such as gender, comorbidities or concomitant medications. Current EULAR (Zhang W, ARD 2006) and ACR (Khanna D, AC&R 2012) recommendations guidelines support initiation urate-lowering medications depending on renal function, presence tophi, number episodes acute inflammation, but to risk for developing severe gout,...
<h3>Background</h3> a definite diagnosis for gout and pyrophosphate arthritis require identification of urate crystals in biolόgica samples. That might explain why databases do not capture with acuracy the coexistence both diseases. <h3>Objectives</h3> to evaluate patients crystal-proved prevalence hiperuricemia arthritis, along those factors associated. <h3>Methods</h3> analysis data from cohort prospective follow-up (PPA) whom were collected at diagnosis. Diagnosis was base don observation...
<h3>Background</h3> An increased risk (OR 4.1, 95% CI 1.8-9.2) of acute inflammation episodes during hospital admission in patients with gout, has been reported an online survey (1). Less than half the were on urate lowering therapy (ULT); those treated levels uricaemia and adequacy treatment are unknown. The authors9 advice was to administer preventive admissions. <h3>Objectives</h3> To evaluate time-associated impact ULT, gout without <h3>Methods</h3> Case-control study within a nested...
<h3>Background</h3> Gout is the most frequent inflammatory arthritis in males, and therefore a common cause for consultation both primary care specialist settings. Despite its frequency, diagnosis treatment this condition are far from desirable (1, 2). There evidence of gout management improvement through educational programs targeted at physicians (3). <h3>Objectives</h3> To measure impact diagnostic therapeutic attitudes towards patients with gout, physicians, before after performing an...
<h3>Background</h3> Several metabolic disturbances that reduce the activity of pyrophosphatases have been associated with development calcium pyrophosphate crystal arthritis (CPPCA), but there is scarce data on their influence clinical manifestations, as such disease-specific variables are not recorded in most available databases. <h3>Objectives</h3> To evaluate factors to severity joint involvement patients definite CPPCA. <h3>Methods</h3> Transversal study prospective recruitment cases...
<h3>Background:</h3> Rheumatology is a relatively new medical specialty, and mostly unknown to the general population. Thanks close collaboration between rheumatologists primary care physicians (PCP), availability of revolutionary drugs in last decades, it has become fundamental part management patients with musculoskeletal disorders. Besides information PCP, equally important that population aware what rheumatology is, diseases treats. We decided inform about most prevalent disorders:...