A5082450208- Heart Rate Variability and Autonomic Control
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- European Political History Analysis
- Historical Studies and Socio-cultural Analysis
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular and exercise physiology
- Non-Invasive Vital Sign Monitoring
- Monetary Policy and Economic Impact
- Sleep and related disorders
- Global Financial Crisis and Policies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular and Diving-Related Complications
- Nutrition and Health in Aging
- Sleep and Wakefulness Research
- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Economic theories and models
- Health, Medicine and Society
- Cardiac Arrhythmias and Treatments
- Physical Activity and Health
- Economic Theory and Policy
- French Urban and Social Studies
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
Inserm
2021-2025
Université Jean Monnet
2015-2024
Biologie, ingénierie et imagerie pour l'Ophtalmologie
2013-2024
Centre Hospitalier Universitaire de Saint-Étienne
2015-2024
Banque de France
2011-2024
Mines Saint-Étienne
2023
Institute Cancer De La Loire Lucien Neuwirth
2016-2023
École Normale Supérieure
2023
University Research Co (United States)
2023
Université Claude Bernard Lyon 1
2013-2022
Background —Enhanced nocturnal heart rate variability (HRV) has been evoked in sleep-related breathing disorders. However, its capacity to detect obstructive sleep apnea syndrome (OSAS) not systematically determined. Thus, we evaluated the discriminant power of HRV parameters a first group patients (G1) and validated their second (G2). Methods Results —In G1, 39 91 (42.8%) were identified as diseased by polysomnography, 24 52 (46%) G2. Time-domain variables (SD NN intervals [SDNN], mean...
Heart rate variability is a recognized parameter for assessing autonomous nervous system activity. Fourier transform, the most commonly used method to analyze variability, does not offer an easy assessment of its dynamics because limitations inherent in stationary hypothesis. Conversely, wavelet transform allows analysis nonstationary signals. We compared respective yields and transforms analyzing heart during dynamic changes balance induced by atropine propranolol. were applied sequences...
Abstract Aim To evaluate the long‐term sealing ability of four contemporary endodontic sealers [Pulp Canal Sealer (PCS), AH‐Plus, GuttaFlow and Epiphany] using a fluid filtration technique. Methodology The palatal roots 40 human maxillary molar teeth were selected root canal was prepared crown‐down technique (apical size 40, 6% taper). Roots irrigated with 3% NaOCl, 17% EDTA solution rinsed distilled water. Canals filled either PCS, or Epiphany single‐cone ( n = 8). Twenty‐four hours after...
Background— Premature atrial contractions (PACs) are independent predictors of fibrillation, stroke, and death. However, little is known about PAC frequency in the general population its association with other cardiovascular risk factors. Methods Results— We performed a cross-sectional analysis among participants population-based Swiss cohort Study on Air Pollution Lung Diseases Adults (SAPALDIA). 24-hour Holter electrocardiograms to assess prevalence were random sample 1742 aged ≥50 years....
Sleep related breathing disorders (SRBD) are risk factors for cognitive dysfunction in middle-aged subjects, but this association has not been observed the elderly. We assess impact of SRBD on performance a large cohort healthy elderly subjects. Cross-sectional study examining between subjective memory test, neuropsychological battery testing and Community-based sample home research clinical settings. 827 58.5% women, aged 68 y at entry, participated study. All were free previously diagnosed...
Since the pioneering studies of 1960s, heart rate variability (HRV) has become an increasingly used non-invasive tool for examining cardiac autonomic functions and dysfunctions in various populations conditions. Many calculation methods have been developed to address these issues, each with their strengths weaknesses. Although its interpretation may remain difficult, this technique provides, from a approach, reliable physiological information that was previously inaccessible, many fields...
One of the most noticeable effects aging is reduction in skeletal muscle mass and strength (sarcopenia). The metabolic syndrome (MS) also prevalent old subjects, but its relevance to characteristics has poorly been investigated. Immunohistochemical studies were performed with biopsies from young (22 years) (73 men without MS reveal age-dependent MS-associated modifications fiber-type characteristics. Atrophy type II fibers altered fiber shape characterized lean healthy men. In contrast,...
AimsSleep fragmentation is a landmark of sleep disorders, because microarousals are systematically associated with sympathetic surges (i.e. arousals). However, the impact on blood pressure (BP) remains understudied. We assessed relationships between 24 h ambulatory BP monitoring, autonomic arousal index (AAI) derived from pulse transit time, and heart rate variability indices. hypothesized that repeated arousals during elevated in large population elderly volunteers.
The relationship between obstructive sleep apnea syndrome (OSAS), cardiac arrhythmias, and conduction disturbances in adults remains controversial. Early studies showed a higher prevalence than more recent designed epidemiological studies. To clarify the actual of arrhythmias patients referred for assessment OSAS, prospective cohort study was conducted: 147 consecutive (103 men; mean age 54.5 +/- 10.7 years) underwent time-synchronized polysomnography ECG Holter monitoring. OSAS diagnosed 66...
(i) To report associations between cardiovascular risk factors and heart rate variability (HRV) in a general population (ii) to provide normal values for various HRV measurements healthy European sample aged >or=50.Twenty-four-hour electrocardiograms were recorded 1742 randomly selected SAPALDIA (Swiss cohort study on Air Pollution Lung Diseases Adults) participants >or=50. In multivariate regression analyses, women (n=895) had 6.1% lower standard deviation of all RR (NN) intervals (SDNN),...
There is no published randomized study comparing amiodarone therapy and radiofrequency catheter ablation (RFA) after only 1 episode of symptomatic atrial flutter (AFL). The aim the Loire-Ardèche-Drôme-Isère-Puy-de-Dôme (LADIP) Trial Atrial Flutter was 2-fold: (1) to prospectively compare first-line RFA (group I) versus cardioversion II) AFL episode; (2) determine impact both treatments on long-term risk subsequent fibrillation (AF).From October 2002 February 2006, 104 patients (aged 78+/-5...
<i>Background:</i> Transversal studies have underlined the association between decline in autonomic nervous system (ANS) activity and all-cause mortality. However, predictive value of ANS has never been prospectively assessed a general population-based cohort. <i>Method:</i> The PROOF (PROgnostic indicator OF cardiovascular cerebrovascular events) cohort study was designed to assess level population, with regard events, death. This power will be compared usual newly...
Recent evidence suggests that autonomic nervous system activity could be involved in the pathophysiology of sickle cell disease, but it is unclear whether differences are detectable during steady state patients with mild and severe disease. The aim present study was to compare activity, blood rheology, inflammation anemia according frequency acute pain crisis.Twenty-four healthy volunteers, 20 milder 15 more disease were recruited. Milder defined as having no crisis within previous year....
BackgroundThe occurrence of restless legs syndrome (RLS) in elderly individuals is well known but the incidence and clinical correlates these subjects are still unclear. The present study explores prevalence assesses symptoms associated with RLS an older French population.
Obstructive sleep apnoea (OSA) affects females and males differently, increases in prevalence with age. The aim of the present study was to characterise clinical, anthropometric polygraphic sex differences a large elderly OSA population. A total 641 subjects aged 68 yrs were examined. Measurements fat mass, using dual-energy X-ray absorptiometry (DEXA) polygraphy, obtained all subjects. An apnoea/hypopnoea index (AHI) >15 events·h −1 identified presence OSA. diagnosed 57% sample, 34%...
Sleep breathing disorder (SBD) may be an important factor in age-related cognitive decline. In a cohort of healthy elderly subjects, we performed 8-y longitudinal study to assess whether changes function occur untreated patients with SBD and without dementia the factors implicated these changes.
Tobacco use is the single largest preventable risk factor for premature death of non-communicable diseases and second leading cause cardiovascular disease. In response to harmful effects tobacco smoking, electronic cigarettes (e-cigarettes) has emerged gained significant popularity over past 15 years. E-cigarettes are promoted as safe alternatives traditional smoking often suggested a way reduce or quit smoking. However, evidence suggests they not harmless.The rapid evolution e-cigarette...