A5044245258- Photosynthetic Processes and Mechanisms
- Spectroscopy and Quantum Chemical Studies
- Photoreceptor and optogenetics research
- Genomics and Chromatin Dynamics
- Cell Image Analysis Techniques
- Advanced biosensing and bioanalysis techniques
- DNA and Nucleic Acid Chemistry
- Radiomics and Machine Learning in Medical Imaging
- Photochemistry and Electron Transfer Studies
- Blood groups and transfusion
- Gastrointestinal Tumor Research and Treatment
- Lanthanide and Transition Metal Complexes
- Molecular spectroscopy and chirality
- Photodynamic Therapy Research Studies
- Advanced NMR Techniques and Applications
- Epigenetics and DNA Methylation
- Antioxidant Activity and Oxidative Stress
- RNA modifications and cancer
- Analytical Methods in Pharmaceuticals
- Analytical chemistry methods development
- Metastasis and carcinoma case studies
Queen's University
2022-2023
Queen Mary University of London
2019-2022
Beijing University of Chinese Medicine
2018
Nucleosomes, containing histone variants H2A.Z, are important for gene transcription initiation and termination, chromosome segregation DNA double-strand break repair, among other functions. However, the underlying mechanisms of how H2A.Z influences nucleosome stability, dynamics accessibility not well understood, as experimental computational evidence remains inconclusive. Our modeling efforts human stability dynamics, along with comparisons data show that incorporation results in a...
In some molecular systems, such as nucleobases, polyenes or sunscreens, substantial amounts of photo-excitation energy are dissipated on a sub-picosecond time scale. Where does this go among which degrees freedom it is being distributed at early times?
Higher plants defend themselves from bursts of intense light via the mechanism Non-Photochemical Quenching (NPQ). It involves Photosystem II (PSII) antenna protein (LHCII) adopting a conformation that favors excitation quenching. In recent years several structural models have suggested quenching proceeds energy transfer to optically forbidden and short-lived S 1 states carotenoid. was proposed this pathway controlled by subtle changes in relative orientation small number pigments. However,...
Carotenoid optical properties are often explained in terms of molecular symmetry. We find that the two unrelated and certain key robust despite severe distortions due to interactions with proteins.
We characterize the photophysical interactions between lipid-linked chromophores and plant light-harvesting proteins incorporated into nanodiscs using optical spectroscopy, simulations theoretical modelling.
Abstract Nucleosomes containing the histone variant H2A.Z are important for gene transcription initiation and termination, chromosome segregation DNA double-strand break repair, among other functions. However, underlying mechanism of how influences nucleosome stability, dynamics accessibility remains elusive as experimental computational evidence inconclusive. Our modeling efforts stability dynamics, along with comparisons data show that incorporation results in a substantial decrease energy...
Abstract Higher plants defend themselves from bursts of intense light via the mechanism Non-Photochemical Quenching (NPQ). It involves Photosystem II (PSII) antenna protein (LHCII) adopting a conformation that favours excitation quenching. In recent years several structural models have suggested quenching proceeds energy transfer to optically forbidden and short-lived S 1 states carotenoid. was proposed this pathway controlled by subtle changes in relative orientation small number pigments....
Light-Harvesting Complex II (LHCII) is a membrane protein found in plant chloroplasts that has the crucial role of absorbing solar energy and subsequently performing excitation transfer to reaction centre subunits Photosystem II. LHCII provides strong absorption blue red light, however, it minimal green spectral region where irradiance maximal. In recent proof-of-principle study, we enhanced this range by developing biohybrid system proteins together with lipid-linked Texas Red (TR)...
Objective To investigate the relationship between total serum IgG concentration and tumor progression in patients with gastric cancer. Methods From January 2010 to May 2017, a of 90 cancer Sun Simiao Hospital Beijing University Chinese Medicine were enrolled as study subjects age-and-sex-matched adults from normal physical examination control subjects. The subgroup concentrations measured by enzyme-linked immunosorbent assay. relationships clinicopathologic features analyzed. numbers...
Light-Harvesting Complex II (LHCII) is a membrane protein found in plant chloroplasts that has the crucial role of absorbing solar energy and subsequently performing excitation transfer to reaction centre subunits Photosystem II. LHCII provides strong absorption blue red light, however, it minimal green spectral region where irradiance maximal. In recent proof-of-principle study, we enhanced this range by developing biohybrid system proteins together with lipid-linked Texas Red (TR)...