A5100326125- Nanomaterials for catalytic reactions
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Catalytic Processes in Materials Science
- Advanced Photocatalysis Techniques
- Cancer-related molecular mechanisms research
- Metal complexes synthesis and properties
- RNA modifications and cancer
- Luminescence Properties of Advanced Materials
- Cancer Mechanisms and Therapy
- RNA and protein synthesis mechanisms
- DNA and Nucleic Acid Chemistry
- Cancer-related gene regulation
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Genomics and Chromatin Dynamics
- Vanadium and Halogenation Chemistry
- Perovskite Materials and Applications
- Cancer, Hypoxia, and Metabolism
- Advanced biosensing and bioanalysis techniques
- Ubiquitin and proteasome pathways
- Protein Hydrolysis and Bioactive Peptides
- Environmental remediation with nanomaterials
- Natural product bioactivities and synthesis
- Advanced oxidation water treatment
Anhui University of Traditional Chinese Medicine
2024-2025
Guangdong Pharmaceutical University
2011-2024
National Institute for Viral Disease Control and Prevention
2017-2024
Zhongshan Hospital of Xiamen University
2012-2024
Xuzhou Medical College
2023-2024
The First People’s Hospital of Lianyungang
2024
Xian Yang Central Hospital
2024
Shenzhen Second People's Hospital
2024
Chinese Center For Disease Control and Prevention
2022-2024
Fujian Medical University
2012-2024
Unlike inorganic crystals, metal-organic frameworks do not have a well-developed nanostructure library, and establishing their appropriately diverse complex architectures remains major challenge. Here, we demonstrate general route to control framework structure by solvent-assisted ligand exchange approach. Thirteen different types of structures been prepared successfully. To proof concept application, used the obtained materials as precursors for synthesizing nanoporous carbons investigated...
Background/Aims: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and a leading cause of cancer-related death worldwide. Luteolin, flavonoid from traditional Chinese medicine, shows anti-cancer activity in many cancer cells, including HCC. However, mechanism underlying action luteolin HCC, especially its role regulating cell autophagy, remains unclear. In present study, we investigated autophagy luteolin-induced apoptosis. Methods: The...
Zika virus (ZIKV) infection causees neurologic complications, including Guillain-Barré syndrome in adults and central nervous system (CNS) abnormalities fetuses. We investigated the immune response, especially CD8+ T cell response C57BL/6 (B6) wild-type (WT) mice, during ZIKV infection. found that a robust was elicited, major histocompatibility complex class I-restricted epitopes were identified, tetramer recognizes ZIKV-specific cells developed, virus-specific memory generated these mice....
Sensitive detection of cancer biomarkers can contribute to the timely diagnosis and treatment diseases. In this study, whitespotted bamboo sharks were immunized with human α-fetoprotein (AFP), a phage-displayed variable new antigen receptor (VNAR) single domain antibody library was constructed. Then four unique VNARs (VNAR1, VNAR11, VNAR21, VNAR25) against AFP isolated from by biopanning for first time. All sequences belong type II VNAR, VNAR11 much different rest three sequences. VNAR1...
Recognition of DNA by proteins relies on direct interactions with specific DNA-functional groups, along indirect effects that reflect variable energetics in the response sequences to twisting and bending distortions induced proteins. Predicting readout requires knowledge variations curvature flexibility affected region, which we have determined for a series DNA-binding sites E2 regulatory protein using cyclization kinetics method. We examined 16 containing different noncontacted spacer...
Chromatin remodeling complexes (remodelers) are large, multisubunit macromolecular assemblies that use ATP hydrolysis to alter the structure and positioning of nucleosomes. The mechanisms proposed for remodeler action on nucleosomes diverse, require structural evaluation insights. Previous reconstructions remodelers using electron microscopy revealed interesting features, but also significant discrepancies, prompting new approaches. Here, we orthogonal tilt reconstruction method, which is...
The insulin-like growth factor-2 mRNA-binding protein 3 (IGF2BP3) is a member of highly conserved family that expressed specifically in placenta, testis and various cancers, but hardly detectable normal adult tissues. IGF2BP3 has important roles RNA stabilization translation, especially during early stages both human mouse embryogenesis. Placenta an indispensable organ mammalian reproduction connects developing fetus to the uterine wall, responsible for nutrient uptake, waste elimination gas...
// Yongli Zhang 1 , Wei Bao 2 Kai Wang Wen Lu Huihui Huan Tong 3 Xiaoping Wan Department of Obstetrics and Gynecology, Shanghai First Maternity Infant Hospital, Tongji University School Medicine, Shanghai, China International Peace & Child Health Hospital Affiliated to Jiao People's University, Correspondence to: Wan, email: wanxiaoping@tongji.edu.cn Keywords: SOX17, MAML3, endometrial cancer, β-catenin, Wnt signaling Received: January 10, 2016 Accepted: September 26, Published: October 12,...
Abstract Background Chimeric antigen receptor-T (CAR-T) cells therapy is one of the novel immunotherapeutic approaches with significant clinical success. However, their applications are limited because long preparation time, high cost, and interpersonal variations. Although manufacture universal CAR-T (U-CAR-T) have significantly improved, they still not a stable unified cell bank. Methods Here, we tried to further improve convenience flexibility U-CAR-T by constructing modular (MU-CAR-T)...
Psoriasis is a chronic skin disease caused by the interaction of multiple factors that leads to abnormal growth stratum corneum cells and has been called an immortal cancer. Docetaxel trialed for treatment psoriasis due its superior ability induce apoptosis, but insolubility low bioavailability have hampered development. Here, docetaxel (DTX)-loaded liposomes-in-gel (DTX-LP-G) as transdermal delivery was investigated via modulating IL6-HIF-1α-VEGF axis. The results demonstrated DTX-LP-G...
// Fei-Zhou Jiang 1,* , Yin-Yan He Hui-Hui Wang 2 Hui-Lin Zhang 1 Jian Xiao-Fang Yan Xiao-Jun Qi Che Jie-Qi Ke Zheng Chen Huan Tong Yong-Li Fang-Yuan Yi-Ran Li and Xiao-Ping Wan 1,3 Department of Obstetrics Gynecology, Shanghai General Hospital, Jiao University School Medicine, Shanghai, China Jiaotong University Affiliated International Peace Maternity & Child Health Hospital the Welfare Institute, 3 First Infant Tongji School * These authors have contributed equally to this work...
Fe-Co-Ce composite catalysts were prepared by coprecipitation method using CO(NH 2 ) , NaOH, NH 4 HCO 3 and ·H O as precipitant agents. The effects of the agents on physicochemical properties based investigated SEM, TEM, BET, TG-DTA, XRD. It was found that remarkably influenced morphology particle size affected COD removal efficiency, decolorization rate, pH methyl orange for catalytic wet air oxidation (CWAO). specific surface area successively decreased in order O, which correlated to an...
Enhanced photoluminescence properties and confirmed energy transfer in a YAGO:Mn<sup>4+</sup>,Dy<sup>3+</sup> phosphor.
Facial nerve (FN) injury seriously affects human social viability and causes a heavy economic burden. Although mesenchymal stem cell-derived exosomes (MSC-Exos) promise therapeutic benefits for repair, there has been no evaluation of the impact MSC-Exos administration on FN repair. Herein, we explore function in immunomodulation macrophages their effects repairing injury. An ultracentrifugation technique was used to separate from MSC supernatant. Administrating SD rats via local injection...
Abstract An unsymmetrical oxovanadium complex [VO(SAA)(phen)] (1) (SAA = salicylidene anthranilic acid, phen phenanthroline) and its derivative [VO(MOSAA)(phen)] (2) (MOSAA 2-hydroxy-4-methoxysalicylidene anthranilic) have been synthesized characterized by elemental analysis, UV-Vis, ES-MS, IR, 1H NMR. The interaction of these two complexes with calf thymus DNA (CT-DNA) was investigated absorption titration, fluorescence spectra, viscosity measurements, thermal denaturation. Their...