Ismael Z. Assi

ORCID: 0000-0003-4310-7396
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About
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Research Areas
  • Venous Thromboembolism Diagnosis and Management
  • Diagnosis and Treatment of Venous Diseases
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Health and Disease Prevention
  • Congenital Heart Disease Studies
  • Cardiac Structural Anomalies and Repair
  • Advanced X-ray and CT Imaging
  • Coronary Interventions and Diagnostics
  • Vascular anomalies and interventions
  • Coronary Artery Anomalies
  • Central Venous Catheters and Hemodialysis
  • Cerebrovascular and Carotid Artery Diseases

University of Michigan
2023-2024

University of Cincinnati
2024

Introduction: Iliac vein compression syndrome (IVCS) is present in over 20% of the population and associated with left leg pain, swelling, thrombosis. IVCS symptoms are thought to be induced by altered pelvic hemodynamics, however, there currently exists a knowledge gap on hemodynamic differences between healthy patients. To elucidate those differences, we carried out patient-specific, computational modeling comparative study. Methods: Computed tomography ultrasound velocity area data were...

10.3389/fbioe.2024.1302063 article EN cc-by Frontiers in Bioengineering and Biotechnology 2024-01-18

Elevated shear rates are known to play a role in arterial thrombosis; however, have not been thoroughly investigated patients with iliac vein compression syndrome (IVCS) owing imaging limitations and assumptions on the low nature of venous flows. This study was undertaken develop standardized protocol that quantifies IVCS can aid diagnosis treatment moderate yet symptomatic compression.Study without had their hemodynamics measured via duplex ultrasound (US) at two following three vessel...

10.1016/j.jvsv.2023.05.017 article EN publisher-specific-oa Journal of Vascular Surgery Venous and Lymphatic Disorders 2023-06-22

Introduction: Current assessment/management of internal carotid artery (ICA) stenosis is based on estimation percentage (%) which does not account for trans-lesional flow, pressure gradient (PG), wall shear stress (WSS), or oscillatory index (OSI). Computation fluid dynamics (CFD) can be used to characterize such indices. Hypothesis: We hypothesize that patients asymptomatic >70% ICA will have hemodynamic differences are independent % stenosis. Aims: Evaluate indices in with via CFD....

10.1161/atvb.44.suppl_1.1145 article EN Arteriosclerosis Thrombosis and Vascular Biology 2024-05-01

Adequate blood flow through the coronary tree is critical for maintaining cardiac perfusion. Coronary angiography has potential to provide rich and dynamic hemodynamic information, however, current strategies assess vessels depend on either subjective expert opinion (TIMI grade) or laborious frame-by-frame anatomical analysis frame count quantitative ratio). Here we present a strategy automated characterization of bulk using right artery as an example. We leverage AngioNet neural network...

10.1101/2024.12.03.24318433 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-12-05

Coronary Artery Disease (CAD) and Microvascular (CMD) can lead to insufficient blood flow the myocardium, affecting millions of people globally. angiography, one most commonly used imaging modalities, offers valuable information that assists in diagnosing these diseases. However, benefits are not fully understood or utilized current clinical practice. In this study, a 3D-0D coupled multi-physics computational fluid dynamics (CFD) model was developed calibrated simulate better understand...

10.48550/arxiv.2412.04798 preprint EN arXiv (Cornell University) 2024-12-06
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