A5008650163- Immunodeficiency and Autoimmune Disorders
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Kawasaki Disease and Coronary Complications
- Mycobacterium research and diagnosis
- Vasculitis and related conditions
- Tuberculosis Research and Epidemiology
- Hemophilia Treatment and Research
- Blood Coagulation and Thrombosis Mechanisms
- Urticaria and Related Conditions
- Autoimmune and Inflammatory Disorders Research
- Blood disorders and treatments
- Inflammasome and immune disorders
- Sexual function and dysfunction studies
- Chronic Lymphocytic Leukemia Research
- Neonatal and Maternal Infections
- Cell Adhesion Molecules Research
- Mast cells and histamine
- Autoimmune and Inflammatory Disorders
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Neonatal and fetal brain pathology
- Parvovirus B19 Infection Studies
- Dermatological and Skeletal Disorders
- Coronary Artery Anomalies
- Immune Cell Function and Interaction
- Infant Development and Preterm Care
Post Graduate Institute of Medical Education and Research
2021-2025
Institute of Post Graduate Medical Education and Research
2022-2024
Burdwan Medical College & Hospital
2016-2021
KPC Medical College and Hospital
2013-2016
Hereditary angioedema (HAE) is characterized by unpredictable acute attacks that impair the patient's quality of life (QoL) not only due to impact on functional abilities caused edema but also pain and other symptoms, including fatigue, nausea, vomiting. QoL studies in patients with HAE have been carried out Indian subcontinent. Hence, we this study assess identify factors associated impaired HAE. This was a cross-sectional observational confirmed cases HAE, aged >18 years, using score...
Hereditary angioedema (HAE) is an uncommon disorder characterized clinically by recurrent episodes of nonitchy subcutaneous and/or submucosal swellings. The estimated prevalence HAE ~ 1: 10,000 to 50,000. There are no data from India, however, estimates suggest that there 27,000 135,000 patients with in India at present. majority these, remain undiagnosed. Replacement plasma-derived or recombinant C1-esterase inhibitor (C1-INH) protein, administered intravenously, the treatment choice during...
Background: Birth injuries are mechanical traumas which occur during the process of labor and delivery. The reported incidence varies widely, various predisposing maternal, neonatal, labor-related risk factors documented. However, prospective analysis epidemiological from India is limited. Objective: To delineate incidence, factor, outcome birth in our tertiary level teaching referral hospital. Design: Prospective observational study. Setting: Neonatology Divisions Department Pediatric...
Kawasaki disease (KD) is a common childhood systemic vasculitis with special predilection for coronary arteries. Even after more than five decades of the initial description disease, etiology KD remains an enigma. This transcriptome data re-analysis study aimed to elucidate underlying pathogenesis using bioinformatic approach identify differentially expressed genes (DEGs) delineate pathways involved in KD. Array datasets from Gene Expression Omnibus database were extracted and subjected...
Hereditary angioedema (HAE) is a rare genetic disease. Patients with type II HAE have normal or elevated C1-inhibitor (C1-INH) levels but C1-INH protein dysfunctional. function requires careful sample handling and technical expertise may account for the lack of diagnosed patients in resource-limited countries.We sought to assess diagnostic performance diagnosing HAE.All confirmed Hong Kong India were analyzed. Diagnosis was by persistent low and/or pathogenic SERPING1 gene mutations. Their...
Ours was a descriptive observational cross-sectional study carried out in tertiary care hospital eastern India over period of one year to the profile neurological involvement paediatric dengue patients. Of 71 laboratory-confirmed cases, 20 (28.17%) had involvement. Common forms observed were acute encephalopathy (40%), encephalitis (30%), pure motor weakness (15%), transverse myelitis (5%), disseminated encephalomyelitis (5%) and Guillain–Barré syndrome (5%). The IgM antibody could be...
Hereditary angio-oedema (HAE) is a rare autosomal dominant disorder characterized clinically by recurrent episodes of nonpruritic subcutaneous and/or submucosal oedema. Laryngeal oedema the commonest cause mortality in patients with HAE. Prior to availability first-line treatment options for management HAE, was as high 30%. Mortality has significantly declined countries where are available and can access these therapies. There paucity literature on outcomes HAE developing still challenge.
Objective To study the clinical features and laboratory parameters of neonatal lupus erythematosus (NLE) from India. Patients methods We analyzed case records children diagnosed with NLE in Pediatric Rheumatology Clinic at tertiary care centre North India during period January 1999 - December 2023. Results Twenty-four babies are period. Median age diagnosis was 60 days a female predisposition (Male to female- 1:2). Cutaneous manifestations were reported 14 (58%) patients. Hepatomegaly noted...
Birth asphyxia may cause neuro-developmental impairment in the affected newborns especially those who had hypoxic-ischemic encephalopathy. Music therapy has been observed to help reducing pain and stress improve neurodevelopmental outcome.The objective of this study is determine effects music on outcomes birth asphyxia.A randomized controlled trial involving 3095 born between January 2013 August 2019 with was conducted neonatal intensive care unit Burdwan Medical College. They were...
<b><i>Introduction:</i></b> X-linked lymphoproliferative syndrome (XLP) is a rare primary immune deficiency. Two types of XLP have been described: XLP-1 and XLP-2. <b><i>Methods:</i></b> We found 7 patients with (3 had 4 XLP-2) after reviewing the data from Pediatric Immunodeficiency Clinic 1997 to 2021. <b><i>Results:</i></b> Mean age at diagnosis was 3.8 years, mean delay in 2.6 years. Five recurrent episodes...
To document the prevalence and etiology of sustained blood pressure elevation in children. It is a school-based prospective cross-sectional study involving healthy school children age group 5–15 years (both sexes). Children with any acute or chronic illnesses intersexes were excluded from group. Total number hypertensive 37. Of these 37 cases, 23 cases boys 14 girls. All maintained their above +2SD for corresponding sex. Male female ratio was 62:38. primary hypertensives as per working...
Porphyrias are group of disorders caused by deficiency the enzymes in heme synthetic pathway. Congenital erythropoietic porphyria (CEP) is an extremely rare disease with mutation gene that codes for uroporphyrinogen III synthase leading to accumulation porphyrin different tissues and marked cutaneous photosensitivity. Here, we describe a case CEP infancy onset blistering, photosensitivity, red colored urine teeth along scarring but without any feature hemolysis.
Systemic sclerosis is a clinically heterogeneous systemic disease affecting the connective tissues of skin, walls blood vessels and internal organs like lung, heart kidneys. very unusual in pediatric population. Children represent fewer than 10% all cases. We report case 11 years old girl progressive presenting with features cutaneous sclerosis, microstomia, mask-like facies, sclerodactyly, esophageal dysmotility, Raynaud's phenomenon, arthralgia pulmonary fibrosis.
Introduction: Poisoning is an important cause of morbidity and mortality in paediatric age group. Objective this study was to determine the pattern poisoning group respect epidemiological characteristics, aetiology, clinical features a major part South Bengal.Material Methods: This retrospective, observational conducted medicine ward intensive care unit (PICU) Burdwan Medical College from January, 2015 December, 2015.All children less than or equal 12 years who visited emergency with history...
Abstract Background Dedicator of cytokinesis protein 8 (DOCK8) deficiency is an autosomal recessive form combined immunodeficiency. This rare disorder characterized by increased predisposition to allergy, autoimmunity and malignancies. Objectives To analyse clinical, immunological molecular profiles patients with DOCK8 deficiency. Methods Clinic records all attending the primary immunodeficiency clinic from 2018 2021 were reviewed. Six five families found have Results Median age at diagnosis...