A5091242093- Diabetes Management and Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Treatment and Management
- Diabetes Management and Education
- Chronic Kidney Disease and Diabetes
- Diabetes and associated disorders
- Diabetic Foot Ulcer Assessment and Management
- Growth Hormone and Insulin-like Growth Factors
- Metabolism, Diabetes, and Cancer
- Retinal Diseases and Treatments
- Retinopathy of Prematurity Studies
- Blood Pressure and Hypertension Studies
- Lipid metabolism and disorders
- Adrenal and Paraganglionic Tumors
- Liver Disease Diagnosis and Treatment
- Retinal Imaging and Analysis
- Bone health and osteoporosis research
- Pituitary Gland Disorders and Treatments
- Pain Mechanisms and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Bone Metabolism and Diseases
- Thyroid Disorders and Treatments
- Parathyroid Disorders and Treatments
- Health Promotion and Cardiovascular Prevention
- Pressure Ulcer Prevention and Management
King Chulalongkorn Memorial Hospital
2004-2021
Thai Red Cross Society
2021
Chulalongkorn University
2006-2020
University of Massachusetts Chan Medical School
1996-1997
Eastern Virginia Medical School
1995
AIM:To study whether the severity of liver fibrosis estimated by nonalcoholic fatty disease (NAFLD) score can predict all-cause mortality, cardiac complications, and/or complications patients with NAFLD over long-term follow-up. METHODS:A cohort well-characterized diagnosed during period 1980-2000 was identified through Rochester Epidemiology Project.The (NFS) used to separate and without advanced fibrosis.We NFS classify probability as < -1.5 for low probability, > 0.67 intermediate high...
Abstract To determine the diagnostic value of various cutaneous sensory modalities in diabetic neuropathy, we studied perception at dominant hallux 113 subjects (32 normal healthy controls and 81 subjects). The tests included warm cold thermal perception, vibration, touch‐pressure sensation, current testing (CPT). sensitivity each modality when specificity is held greater than 90% was as follows: = 78%, 77%, vibration 88%, tactile‐pressure 5‐Hz CPT 52%, 250‐Hz 48%, 2000‐Hz 56%. Combination...
Recent studies suggest that thyroid-stimulating hormone suppressive doses of thyroid decrease bone mass in humans and growing rats. To determine the long-term effects excessive L-thyroxine administration on femur vertebrae an adult rat model, 20 male Sprague-Dawley rats (20 weeks old) were randomized into two groups. Group 1 received micrograms/100 g body weight ip daily), group 2 normal saline daily for weeks. Femoral lumbar vertebral mineral density measurements performed at 0, 6, 15, 18...
Microalbuminuria (MA) is a risk marker for diabetic nephropathy and cardiovascular (CV) disease (CVD) in patients with diabetes. This study aimed to describe the prevalence of albuminuria, CV factors, treatments renal protection an Asian population type 2 diabetes.This cross-sectional conducted eight countries enrolled normotensive/hypertensive adults diabetes without known proteinuria and/or non-diabetic kidney disease. Exclusion criteria were 1 diabetes, menstruation, pregnancy, acute...
To evaluate the efficacy and safety of adding biphasic insulin aspart 30 (BIAsp30; NovoMix 30) to existing oral antidiabetic agents (OADs) vs. optimizing OADs in a subgroup Western Pacific patients with type 2 diabetes inadequately controlled on monotherapy or combination therapy.This 26-week, multi-centre, open-labelled, randomized, two-arm parallel trial consisted 2-week screening period, followed by 24 weeks treatment. Subjects randomized BIAsp30 treatment (n = 129) received once daily...
Comprehensive glycemic control is necessary to improve outcomes and avoid complications in individuals with diabetes. Self-monitoring of blood glucose (SMBG) a key enabler assessment, providing real-time information that complements HbA1c monitoring supports treatment optimization. However, SMBG under-utilized by patients physicians within the Asia-Pacific region, because barriers such as cost supplies, lack diabetes self-management skills, or concerns about reliability readings. Practice...
OBJECTIVE To determine the prevalence and significance of phospholipid autoantibodies (PLAs) glutamic acid decarboxylase (GAD) in circulation normal patients diabetic with without neuropathy. RESEARCH DESIGN AND METHODS We measured PLAs a total 78 (a group somatic or autonomic neuropathy [n = 40] another 38]), GAD subset 22 patients. RESULTS are found 2% general population. 32% population neuropathy, 88% those 55% retinopathy, 25% established nephropathy. The frequencies immunoglobulins...
<i>Background:</i> POU1F1 is a pituitary transcription factor that plays pivotal role in development and expression of the <i>GH</i>, <i>PRL</i> <i>TSH</i>β genes. Therefore, abnormalities <i>POU1F1</i> gene are known to be responsible for phenotype causing combined hormone deficiency (CPHD) involving growth hormone, prolactin thyrotropin. <i>Methods:</i> We described an 18-year-old Thai man, from consanguineous family,...
We have previously reported that thyroid-stimulating hormone (TSH)-suppressive doses of L-thyroxine (L-T4) decrease femoral, but not vertebral, bone mineral density (BMD) in rats. L-T4-induced decreases BMD were associated with increased expression genes, reflecting osteoblast activity mRNA extracted from whole femurs vertebrae. To document this skeletal selectivity reflected altered activity, we studied gene by situ hybridization 8-wk-old rats treated L-T4 (20 microg x 100 g body wt(-1)...
Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases. Patients are generally advised lifestyle changes with antihyperglycemic agents prescribed. The major drawback prescribing risk hypoglycemia which subsequently impacts on health-related quality life (HRQoL). This study aimed at examining association between previous history and HRQoL. was a multicenter cross-sectional study, conducted from February 2013 to March 2015 5 tertiary care hospitals in Thailand (Srinagarind,...