A5057997842- Microbial Metabolic Engineering and Bioproduction
- Biofuel production and bioconversion
- Algal biology and biofuel production
- Coenzyme Q10 studies and effects
- Biochemical Acid Research Studies
- Lipid metabolism and biosynthesis
- Enzyme Catalysis and Immobilization
- Photosynthetic Processes and Mechanisms
- Fungal and yeast genetics research
- CRISPR and Genetic Engineering
- Steroid Chemistry and Biochemistry
- Advanced battery technologies research
- Metabolomics and Mass Spectrometry Studies
- Enzyme-mediated dye degradation
- Plant Pathogens and Fungal Diseases
- Biotin and Related Studies
- Plant biochemistry and biosynthesis
- Microbial Metabolites in Food Biotechnology
- Plant-Microbe Interactions and Immunity
- Insect Resistance and Genetics
- Enzyme Production and Characterization
- Entomopathogenic Microorganisms in Pest Control
- Hemoglobin structure and function
- Seaweed-derived Bioactive Compounds
- Microbial Metabolism and Applications
Fujian Normal University
2011-2025
Fuzhou University
2017
In this study, renewable tea waste hydrolysate was used as a sole carbon source for carotenoids and lipid production. A novel
The ascomycete fungus Trichoderma reesei was widely used as a biotechnological workhorse for production of cellulases and recombinant proteins due to its large capacity protein secretion. Transgenesis by random integration gene interest (GOI) into the genome T. can generate series strains that express different levels indicated transgene. insertion site GOI plays an important role in ultimate targeted proteins. However, so far no systematic studies have been made identify transgene loci...
Indole-3-acetic acid (IAA) is a critical plant hormone that regulates cell division, development, and metabolism. IAA synthesis in plants plant-associated microorganisms cannot fulfill the requirement for large-scale agricultural production. Here, two novel biosynthesis pathways, tryptamine (TAM) indole-3-acetamide (IAM), were developed production by whole-cell catalysis de novo an engineered Escherichia coli MG1655. When 10 g/L l-tryptophan was used as substrate, MIA-6 strain containing...
Lignocellulose is an abundant waste resource and has been considered as a promising material for production of biofuels or other valuable bio-products. Currently, one the major bottlenecks in economic utilization lignocellulosic materials cost-efficiency converting lignocellulose into soluble sugars fermentation. One way to address this problem seek superior degradation enzymes further improve current yields lignocellulases. In present study, capacity thermophilic fungus Chaetomium...
Farnesol is an acyclic sesquiterpene alcohol present in the essential oils of various plants nature. It has been reported to be valuable medical applications, such as alleviation allergic asthma, gliosis, and edema well anti-cancerous anti-inflammatory effects. Coenzyme Q10 (CoQ10), cofactor aerobic respiratory electron transport chain, attracted growing interest owing its clinical benefits important applications pharmaceutical, food, health industries. In this work, co-production...
This work provides a novel genetic engineering strategy that improves uptake of extracellular 4-hydroxybenzoic acid by heterologously expressing the membrane transport protein PcaK in<italic>R. sphaeroides</italic>for enhancement CoQ<sub>10</sub>production.
Heat-stable antifungal factor (HSAF) isolated from Lysobacter enzymogenes has shown a broad-spectrum of activities. However, little is known about its mode action. In this study, we used the model filamentous fungus Neurospora crassa to investigate mechanism HSAF. We first HSAF treat N. strain at different time points. Spore germination, growth phenotype and differential gene expression analysis were conducted by utilizing global transcriptional profiling combined with genetic physiological...
Background: Temperature sensitive plasmid pBBR1MCS2-Ts, mutated from pBBR1MCS and derived pBBR1, is a broad host range it especially useful for gene targeting integration in various hosts. The copy number (PCN) of temperature mainly depends on the stability plasmid. Objectives: present study aimed at investigating PCN pBBR1MCS2-Ts pBBR1MCS2 permissive (30°C) or nonpermissive (42°C) temperatures. Methods: rep dxs Escherichia coli genome were used as target reference gene. A standard...
Filamentous fungi are a group of eukaryotic microorganisms widely found in nature. Some filamentous have been developed as "cell factories" and extensively used for the production recombinant proteins, organic acids, secondary metabolites due to their strong protein secretion capabilities or effective synthesis many natural products. The growth morphology significantly influences quality quantity fermented Previous research conducted by authors' revealed that an increase hyphal branches...
To enhance the production of glucose oxidase by recombinant Pichia pastoris, two strategies were developed, which namely co-feeding methanol and sorbitol co-expressing protein disulfide isomerase (PDI) Vitreoscialla hemoglobin (VHb). The volumetric activity reached 456 U/mL using strain X33/pPIC9k-GOD, in 5 liter fermentator, with sorbitol, it was 0.2 fold higher than that only feeding methanol. improved obtained PDI-VHb GOD. While fermented a fermentator 716 yield 7 400 mg/L total soluble...