Eric Green
- Distributed and Parallel Computing Systems
- Genetic Associations and Epidemiology
- Cloud Computing and Resource Management
- Advanced Data Storage Technologies
- Stellar, planetary, and galactic studies
- CCD and CMOS Imaging Sensors
- Distributed systems and fault tolerance
- Precipitation Measurement and Analysis
- BRCA gene mutations in cancer
- Nutrition, Genetics, and Disease
- Gamma-ray bursts and supernovae
- Electromagnetic Compatibility and Noise Suppression
- Isotope Analysis in Ecology
- Spacecraft Design and Technology
- Advanced Aircraft Design and Technologies
- Cancer-related gene regulation
- Planetary Science and Exploration
- Security and Verification in Computing
- Aerodynamics and Fluid Dynamics Research
- Peer-to-Peer Network Technologies
- Power Quality and Harmonics
- International Law and Aviation
- Genomics and Rare Diseases
- Rocket and propulsion systems research
- Power Line Communications and Noise
Brigham Young University
2024-2025
Lawrence Livermore National Laboratory
2019-2023
Maze (United States)
2022
North Carolina State University
2012
ABSTRACT Population isolates such as Finland provide benefits in genetic studies because the allelic spectrum of damaging alleles any gene is often concentrated on a small number low-frequency variants (0.1% ≤ minor allele frequency < 5%), which survived founding bottleneck, opposed to being distributed over much larger ultra--rare variants. While this advantage well-- established Mendelian genetics, its value common disease genetics has been less explored. FinnGen aims study genome and...
PURPOSE Family history (FH) and pathogenic variants (PVs) are used for guiding risk surveillance in selected high-risk women but little is known about their impact breast cancer screening on population level. In addition, polygenic scores (PRSs) have been shown to efficiently stratify through combining information common genetic factors into one measure. METHODS longitudinal real-life data, we evaluate PRS, FH, PVs stratified screening. Using FinnGen (N = 117,252), linked the Mass Screening...
Abstract Large-scale biobank initiatives and commercial repositories store genomic data collected from millions of individuals, tools to leverage the rapidly growing pool health in disease prevention are needed. Here, we describe derivation validation genomics-enhanced risk for two common cardiometabolic diseases, coronary heart type 2 diabetes. Data used our analyses include FinnGen study (N = 309,154) UK Biobank project 343,672). The integrate contemporary genome-wide polygenic scores with...
Leadership supercomputers feature a diversity of storage, from node-local persistent memory and NVMe SSDs to network-interconnected flash HDD. Memory mapping files on different tiers storage provides uniform interface in applications. However, system-wide services like mmap are optimized for generality lack flexibility enabling application-specific optimizations. In this work, we present UMap enable user-space page management that can be easily adapted access patterns applications...
Abstract Earth Trojan asteroids are an important but elusive population that co-orbit with at the L4 and L5 Lagrange points. There is only one known, a large theoretically stable could provide insight into our solar system’s past present, as well planetary defense. In this paper, we present results of survey uses novel shift-and-stack detection method on 2 nights data from Dark Energy Camera. We find no new asteroids. calculate upper limit consistent previous searches despite much less sky...
As astronomical photometric surveys continue to tile the sky repeatedly, potential pushdetection thresholds fainter limits increases; however, traditional digital-tracking methods cannotachieve this efficiently beyond time scales where motion is approximately linear. In paper weprototype an optimal detection scheme that samples under a user defined prior on parameterizationof space, maps these sampled trajectories data and computes optimalsignal-matched filter for computing signal noise...
Performance tuning of High-Performance Computing (HPC) applications depends on sophisticated parameters diverse architectures. These are made available by vendors through low-level dials such as model-specific registers (MSRs). While the MSRs themselves provide a powerful mechanism for users to monitor and control processor features, accessing them is laborious due lack standard interfaces clear documentation. As result, burden determining which consider how fine-tune an application lies...
The presence of multiple harmonics in the power line due to various non-linear loads like adjustable speed drives, computers, fax machine, PLC's, etc. requires high frequency switching an active filter inverter so as reduce harmonic content at point common coupling (PCC) be typically lower than 5% specified by IEEE 519 standards. In this paper, Field Programmable Analog Array (FPAA) based analog controller has been used implement a Synchronous Reference Frame (SRF) algorithm for current...
Leadership supercomputers feature a diversity of storage, from node-local persistent memory and NVMe SSDs to network-interconnected flash HDD. Memory mapping files on different tiers storage provides uniform interface in applications. However, system-wide services like mmap are optimized for generality lack flexibility enabling application-specific optimizations. In this work, we present Umap enable user-space page management that can be easily adapted access patterns applications...