A5056404326- Diabetes, Cardiovascular Risks, and Lipoproteins
- Adipose Tissue and Metabolism
- Regulation of Appetite and Obesity
- Diet and metabolism studies
- Cardiovascular Function and Risk Factors
- Lipoproteins and Cardiovascular Health
Radboud University Nijmegen
2020
Radboud University Medical Center
2020
Allen Institute for Brain Science
2019
The obesity epidemic increases the interest to elucidate impact of short-chain fatty acids on metabolism, obesity, and brain. We investigated effects propionic acid (PA) caproic (CA) metabolic risk factors, liver adipose tissue pathology, brain function, structure (by MRI), gene expression, during development in Ldlr−/−.Leiden mice. mice received 16 weeks either a high-fat diet (HFD) induce or chow as reference group. Next, obese HFD-fed were treated 12 with (a) HFD + CA (CA), (b) PA (PA),...