A5026196291- Electrospun Nanofibers in Biomedical Applications
- Advanced Chemical Sensor Technologies
- Conducting polymers and applications
- Advanced Sensor and Energy Harvesting Materials
- Polydiacetylene-based materials and applications
- biodegradable polymer synthesis and properties
- Electrochemical sensors and biosensors
- Analytical Chemistry and Sensors
- Mass Spectrometry Techniques and Applications
- Gas Sensing Nanomaterials and Sensors
- Metabolomics and Mass Spectrometry Studies
- Luminescence and Fluorescent Materials
- Biosensors and Analytical Detection
- Hydrogels: synthesis, properties, applications
- Polymer Surface Interaction Studies
- Animal Nutrition and Physiology
- Plant Surface Properties and Treatments
- Polymer crystallization and properties
- Comparative Animal Anatomy Studies
- Photochromic and Fluorescence Chemistry
- Surface Modification and Superhydrophobicity
- Tendon Structure and Treatment
- Biochemical Analysis and Sensing Techniques
- Tissue Engineering and Regenerative Medicine
- Physiological and biochemical adaptations
Ghent University
2016-2024
Ghent University Hospital
2020
Sensors play a major role in many applications today, ranging from biomedicine to safety equipment, where they detect and warn us about changes the environment. Nanofibers, characterized by high porosity, flexibility, large specific surface area, are ideal material for ultrasensitive, fast‐responding, user‐friendly sensor design. Indeed, area increases sensitivity response time of as contact with analyte is enlarged. Thanks flexibility membranes, nanofibrous sensors cannot only be applied...
Fast-response and easy-to-visualize colorimetric nanofibrous sensors show great potential for visual continuous control of external stimuli. This makes them applicable in many fields, including wound management, where nanofibers serve as an optimal support material. In this paper, fast responding user-friendly biocompatible, halochromic are successfully fabricated by incorporating the dyes Methyl Red Rose Bengal inside a chitosan/poly(ε-caprolactone) matrix. The commonly applied dye-doping...
Global food waste is a cross-cutting issue that ranges from agricultural production to storage in households and leads the loss of one-third produced products. Although currently depicted static expiry, best-by, due-by dates provide accurate information on when consume product, these time indications are only valid under ideal conditions. Therefore, there stringent need for easy-to-use sensor applications allow continuous monitoring freshness. This work showcases straightforward effortless...
This work shows the design of highly porous membranes with tunable wettability based on poly(2-n-propyl-2-oxazoline) (PnPrOx) nanofibers. Wicking and advanced contact angle experiments demonstrate high potential for applications requiring specific interactions aqueous media. PnPrOx is a popular member among biocompatible poly(2-oxazoline)s due to its thermoresponsiveness in solutions, enabling production 'smart materials'. On material level, however, many interesting properties this polymer...
Abstract Here, we introduce a novel concept for the fabrication of colored materials with significantly reduced dye leaching through covalent immobilization desired using plasma-generated surface radicals. This plasma coating (PDC) procedure immobilizes pre-adsorbed layer functionalized radical sensitive group on addition caused by short treatment. The non-specific nature radicals allows wide variety dyes including azobenzenes and sulfonphthaleins, groups to avoid significant degradation, be...
Nanofibrous membranes based on polycaprolactone (PCL) have a large potential for use in biomedical applications but are limited by the hydrophobicity of PCL. Blend electrospinning PCL with other suited materials, such as gelatin (Gt) allows design better and new materials. This study investigates possibility blend PCL/Gt nanofibrous which can be used to range novel materials applications. The electrospinnability stability nanofibers from non-toxic acid solvent system investigated. developed...
With increasing toxicity and environmental concerns, electrospinning from water, i.e., waterborne electrospinning, is crucial to further exploit the resulting nanofiber potential. Most water-soluble polymers have inherent limitation of in nanofibers, a tedious chemical cross-linking step required reach stable nanofibers. An interesting alternative route use thermoresponsive polymers, such as poly(N-isopropylacrylamide) (PNIPAM), they are beneath their lower critical solution temperature...
A well-defined FRET system based on heterotelechelic poly(2-ethyl-2-oxazoline) containing pyrene and coumarin 343 was successfully used as fluorescent probe for temperature sensing processed into fibres films showing excellent efficiency.
In recent years, ambient ionization mass spectrometry (AIMS) including laser ablation rapid evaporation IMS, has enabled direct biofluid metabolome analysis. AIMS procedures are, however, still hampered by both analytical, i.e., matrix effects, and practical, sample transport stability, drawbacks that impede coverage. this study, we aimed at developing biofluid-specific sampling membranes (MetaSAMPs) offer a directly applicable stabilizing substrate for AIMS. Customized rectal, salivary,...
The amniotic egg fulfils a critical role in reproduction by serving as an interface between the external environment and embryo. Because non-avian reptiles are rarely incubated, they must be heated by, absorb water from, oviposition site for developing mechanisms which sufficient, but not excess, how these vary with local habitat is largely unknown, despite its significance to their evolution. Here, we first performed histology, Fourier-transform infrared spectroscopy dynamic vapor sorption...
In biomedicine, polymer blends are frequently applied in wound dressing design or drug delivery. Within these applications, poly(2-alkyl/aryl-2-oxazoline)s (PAOx) emerging as a popular matrix due to excellent biocompatibility and miscibility with other polymers. However, much is known of PAOx biocompatible systems, so little the within class. We show remarkable phase separation two important, structurally alike, amorphous PAOx, i.e., poly(2-ethyl-2-oxazoline) poly(2-n-propyl-2-oxazoline),...
Abstract Colorimetric nanofibers provide visual, easy‐to‐interpret sensors for personal use as well advanced applications. The potential of 2‐ n ‐butyl‐2‐oxazoline (B) and 2‐ethyl‐2‐oxazoline (E) statistical copolymers a universal, versatile support platform nanofibrous halochromic sensor design is demonstrated. These polymers are electrospinnable from eco‐friendly solvent systems, while wettability, moist adsorption capacity, water‐solubility the membranes can be easily tuned by changing...
Abstract The development of intelligent photonic systems made stimuli‐responsive materials, i.e., with features tunable and switchable by environmental signals, is gaining increasing attention. Here, the study reports on optical gain based complex arrays nanofibers thermo‐responsive poly(2‐ n ‐propyl‐2‐oxazoline), incorporating a blue‐emitting chromophore. fluorescent component endows in addition to moisture absorption capability polymer. Light amplification found temperature‐...
Nanofibrous scaffolds are widely investigated for tendon tissue engineering due to their porous structure, high flexibility, and the ability guide cells in a preferred direction. Previous research has shown that providing microenvironment similar vivo settings improves regeneration. Therefore, this work, ingenious multicomponent nanoyarn mimic fibrillar tubular structures of tendons developed first time through electrospinning bundling nanoyarns followed by nanofibrous shell around bundle....
An important recent development in the field of optical sensors is increasing use colorimetric nanofibers toward ultrasensitive but user-friendly devices. overview several techniques used to produce nanofibrous provided by Ella Schoolaert, Richard Hoogenboom, and Karen De Clerck article number 1702646. By combining electrospinning with chromogenic agents, specificity for a highly diverse range analytes can be obtained.
In recent years, ambient ionization mass spectrometry (AIMS) including laser ablation rapid evaporation IMS (LA-REIMS), has enabled direct biofluid metabolome analysis. AIMS procedures are however still hampered by both analytical, i.e., matrix effects, and practical, sample transport stability, drawbacks that impede coverage. this study, we aimed at developing biofluid-specific sampling membranes (MetaSAMP®s) offer a directly applicable stabilizing substrate for AIMS. Customized rectal,...