Peter Dubruel

ORCID: 0000-0002-5928-7726
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About
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Research Areas
  • 3D Printing in Biomedical Research
  • Electrospun Nanofibers in Biomedical Applications
  • Bone Tissue Engineering Materials
  • Additive Manufacturing and 3D Printing Technologies
  • Hydrogels: synthesis, properties, applications
  • Tissue Engineering and Regenerative Medicine
  • RNA Interference and Gene Delivery
  • Surface Modification and Superhydrophobicity
  • Polymer Surface Interaction Studies
  • biodegradable polymer synthesis and properties
  • Advanced Sensor and Energy Harvesting Materials
  • Photonic and Optical Devices
  • Microbial Applications in Construction Materials
  • Virus-based gene therapy research
  • Wound Healing and Treatments
  • Concrete and Cement Materials Research
  • Advanced biosensing and bioanalysis techniques
  • Plasma Applications and Diagnostics
  • Innovative concrete reinforcement materials
  • Advanced Polymer Synthesis and Characterization
  • Concrete Properties and Behavior
  • Advanced Fiber Optic Sensors
  • Analytical chemistry methods development
  • Analytical Chemistry and Sensors
  • Silk-based biomaterials and applications

Ghent University
2016-2025

Université Laval
2022

Materials Research Group (United States)
2008-2022

Bavarian Polymer Institute
2022

Institute of Molecular Functional Materials
2022

University of Würzburg
2022

John Wiley & Sons (United States)
2022

Ghent University Hospital
2009-2019

Vrije Universiteit Brussel
2019

Institute of Macromolecular Chemistry
2019

Concrete cracks due to its low tensile strength. The presence of endangers the durability as they generate a pathway for harmful particles dissolved in fluids and gases. Without proper treatment, maintenance costs will increase. Self-healing can prevail small precipitation calcium carbonate further hydration. Therefore, use microfibres is proposed control crack width thus promote self-healing efficiency. In current research, sealing also enhanced by application superabsorbent polymers. When...

10.1177/1045389x12438623 article EN Journal of Intelligent Material Systems and Structures 2012-03-15

In the present work, 3D CAD scaffolds for tissue engineering applications were developed starting from methacrylamide-modified gelatin (GelMOD) using two-photon polymerization (2PP). The cross-linked employing biocompatible photoinitiator Irgacure 2959. Because is derived collagen (i.e., main constituent of ECM), materials mimic cellular microenvironment a chemical point view. addition, by applying 2PP technique, structural properties can also be mimicked. Furthermore, in vitro degradation...

10.1021/bm1015305 article EN Biomacromolecules 2011-03-02

Abstract One of the most promising fields for shape‐memory polymers is biomedical field. Shape‐memory that can be triggered by various (physiological) conditions such as temperature and moisture have been reported, well remotely triggerable make use electromagnetic fields, ultrasound, etc. These shown great promise in vitro studies early vivo studies. Their biocompatibility, some cases biodegradability, renders them excellent candidates minimal invasive surgery design devices. The current...

10.1002/adfm.201909047 article EN Advanced Functional Materials 2020-06-18

In gene therapy, endosomal escape represents a major bottleneck since nanoparticles often remain entrapped inside endosomes and are trafficked toward the lysosomes for degradation. A detailed understanding of barrier would be beneficial developing rational strategies to improve transfection escape. By visualizing individual events in live cells, we obtain insight into mechanistic factors that influence proton sponge-based comparative study, found HeLa cells treated with JetPEI/pDNA...

10.1021/acsnano.7b07583 article EN ACS Nano 2018-03-05

Lepidoptera comprise some of the most devastating herbivorous pest insects worldwide. One promising novel control strategies is exploiting RNA interference (RNAi) mechanism to target essential genes for knockdown and incite toxic effects in species without harming other organisms ecosystem. However, many are refractory oral RNAi, often due rapid degradation ingested dsRNA their digestive system. This case lepidopteran insects, including beet armyworm Spodoptera exigua, which characterized by...

10.3389/fphys.2018.00316 article EN cc-by Frontiers in Physiology 2018-04-04

In the present work, porous gelatin scaffolds were prepared by cryogenic treatment of a chemically cross-linked hydrogel, followed removal ice crystals formed through lyophilization. This technique often leads to gels with less skin. A simple method has been developed solve this problem. The study demonstrates that hydrogel pore size decreased an increasing concentration and cooling rate hydrogel. Variation parameters applied also enabled us develop different morphologies (spherical versus...

10.1021/bm060684o article EN Biomacromolecules 2007-01-05

We report on the feasibility of applying porous gelatin hydrogels, prepared by a novel and controlled cryogenic treatment, as cell-interactive scaffolds for tissue engineering applications. Despite large number publications biomaterial, detailed study screening limited their interaction with panel human cells has, to best our knowledge, not yet been published. In present work, we have evaluated two types that differ in pore geometry size. Type I hydrogels contained top-to-bottom transverse...

10.1021/bm0606869 article EN Biomacromolecules 2007-01-05

The two-photon polymerization (2PP) of photosensitive gelatin in the presence living cells is reported. 2PP technique based on localized cross-linking photopolymers induced by femtosecond laser pulses. availability water-soluble photoinitiators (PI) suitable for crucial applying this method to cell-containing materials. Novel PIs developed our group allow formulations with up 80% cell culture medium. cytocompatibility these was evaluated an MTT assay. results encapsulation show occurrence...

10.1021/la402346z article EN publisher-specific-oa Langmuir 2013-09-16
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