A5083465330- Influenza Virus Research Studies
- Vaccine Coverage and Hesitancy
- COVID-19 Impact on Reproduction
- COVID-19 Clinical Research Studies
- Respiratory viral infections research
- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Streptococcal Infections and Treatments
- Bacterial Infections and Vaccines
- SARS-CoV-2 and COVID-19 Research
- Cardiac, Anesthesia and Surgical Outcomes
- Social Media in Health Education
- Pancreatic and Hepatic Oncology Research
- Hormonal Regulation and Hypertension
- Ethics in Clinical Research
- Renin-Angiotensin System Studies
- Immune responses and vaccinations
- Urinary Tract Infections Management
- Nutrition and Health in Aging
- Otolaryngology and Infectious Diseases
- Dermatology and Skin Diseases
- Aortic aneurysm repair treatments
- Patient-Provider Communication in Healthcare
- Voice and Speech Disorders
- Acne and Rosacea Treatments and Effects
University of Southampton
2018-2024
NIHR Southampton Biomedical Research Centre
2018-2024
Drug Safety Research Unit
2024
University of Portsmouth
2022-2023
Primary Health Care
2023
University Medical Center Utrecht
2021
University Hospital Southampton NHS Foundation Trust
2017-2020
Southampton General Hospital
2016-2020
National Institute for Health Research
2020
NIHR Southampton Respiratory Biomedical Research Unit
2020
Introduction Recent evidence suggests that influenza vaccination may offer protection against COVID-19 severity. Our aim was to quantify the association between status and risk of hospitalisation or all-cause mortality in people diagnosed with COVID-19. Methods A retrospective cohort study using routinely collected health records from patients registered a General Practitioner (GP) practice South West England within Electronic Care Health Information Analytics database. The included 6921...
Introduction: Uptake rates of antenatal vaccination remain suboptimal. Our aims were to determine (1) the acceptability routine among pregnant women, (2) confidence maternity healthcare professionals (HCPs) discussing and (3) HCP opinion regarding optimum site for vaccine administration. Methods: Separate questionnaires women HCPs distributed within 4 national health service (NHS) trusts in South England (July 2017 January 2018). Results: Responses from 314 204 (18% obstetricians, 75%...
Introduction: Respiratory syncytial virus (RSV) is a common cause of infant hospitalization and mortality. With multiple vaccines in development, we aimed to determine: (1) the awareness RSV among pregnant women healthcare professionals (HCPs), (2) attitudes toward clinical trials routine implementation antenatal vaccination. Methods: Separate questionnaires for HCPs were distributed within 4 hospitals South England (July 2017–January 2018). Results: Responses from 314 204 (18%...
Limited recent observational data have suggested that there may be a protective effect of oestrogen on the severity COVID-19 disease. Our aim was to investigate association between hormone replacement therapy (HRT) or combined oral contraceptive pill (COCP) use and likelihood death in women with COVID-19.We undertook retrospective cohort study using routinely collected computerized medical records from Oxford-Royal College General Practitioners (RCGP) Research Surveillance Centre (RSC)...
Online media may influence women's decision to undergo vaccination during pregnancy. The aims of this mixed-methods study were to: (1) examine the portrayal maternal in online and (2) establish perceived target vaccine protection as viewed by pregnant women maternity healthcare professionals (HCPs). articles on (published July-December 2012 or November 2015-April 2016) identified through London School Hygiene & Tropical Medicine's Vaccine Confidence Database thematically analysed....
Background FebriDx is a single-use, analyser-free, point-of-care test with markers for bacterial (C-reactive protein [CRP]) and viral (myxovirus resistance A [MxA]) infection, measured on finger-prick blood sample. Aim As part of larger feasibility study, we explored the views healthcare professionals (HCPs) patients use to safely reduce antibiotic prescriptions lower respiratory tract infections (LRTIs) in primary care. Design & setting Remote semi-structured qualitative interviews were...
Abstract Introduction FebriDx® is a CE-marked, single-use point-of-care test with markers for bacterial [C-reactive protein (CRP)] and viral [myxovirus resistance A (MxA)] infection, using finger-prick blood samples. Results are available after 10–12 min. We explored the usability potential impact of in reducing antibiotic prescriptions lower respiratory tract infection (LRTI) primary care, feasibility conducting randomized controlled trial (RCT). Methods Patients (aged ≥1 year) LRTI deemed...
WHY WAS THIS UPDATE DEVELOPED?The incidence of kidney stone disease (urolithiasis) is rising, with a lifetime risk 10-15%, and recurrence rate 50% within 10 years. 1 Associated complications include significant pain secondary to renal colic, urinary tract infection (UTI) urosepsis, chronic disease.The increasing burden urolithiasis means that optimising its management in primary care important. WHEN TO REFER FOR ACUTE RENAL COLICPatients suspected colic (colicky intermittent abdominal and/or...
Background Sore throat is a common problem and reason for the overuse of antibiotics. A web-based tool that helps people assess their sore throat, through use clinical prediction rules, taking swabs or saliva samples, photographs, has potential to improve self-management help identify those who are most least likely benefit from Objective We aimed develop patients parents carers self-assess symptoms take swabs, samples diagnostic testing. then explored acceptability feasibility using in...
Background Antenatal vaccines are commonly delivered in primary care, yet the views of GPs regarding these programmes have been neglected research to date. Aim To establish attitudes and current practice towards antenatal vaccination their on optimal location for delivery this service. Design setting A multicentre online survey questionnaire. Method questionnaire was sent across England between December 2018 January 2019. Results The majority 1586 responders considered safe (96% influenza,...
Abstract Background Concerns have been raised that angiotensin-converting enzyme-inhibitors (ACE-I) and angiotensin receptor blockers (ARBs) might facilitate transmission of severe acute respiratory syndrome coronavirus 2 leading to more disease (COVID-19) an increased risk mortality. We aimed investigate the association between ACE-I/ARB treatment death amongst people with COVID-19 in first 6 months pandemic. Methods identified a cohort adults diagnosed either confirmed or probable (from 1...
Improving the uptake of vaccination in pregnancy has been highlighted as a priority by World Health Organisation, yet establishing optimal location for delivery antenatal program remains topic debate internationally. In many countries, vaccines are usually delivered within Primary Care (under lead general practitioners [GPs] or family physicians), this often presents logistic barrier to accessing vaccination, and increasing evidence demonstrates that embedding routine care visits may...
Objectives There has been increased interest in screening for atrial fibrillation (AF) with commissioned pilot schemes, ongoing large clinical trials and the emergence of inexpensive consumer single-lead ECG devices that can be used to detect AF. This qualitative study aimed explore patients’ views understanding AF determine acceptability inform future recommendations. Setting A single primary care practice Hampshire, UK. Participants 15 participants (11 female) were interviewed from who had...