A5112550847- Asymmetric Synthesis and Catalysis
- Organic Chemistry Cycloaddition Reactions
- Cancer Cells and Metastasis
- Synthesis and Catalytic Reactions
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Berberine and alkaloids research
- Health Literacy and Information Accessibility
- Research studies in Vietnam
- Soil Management and Crop Yield
- HIV, Drug Use, Sexual Risk
- Adrenal Hormones and Disorders
- Bioactive Compounds and Antitumor Agents
- Chemical Reactions and Isotopes
- Organoboron and organosilicon chemistry
- Sexual Differentiation and Disorders
- Myasthenia Gravis and Thymoma
- Fish Biology and Ecology Studies
- Fish Ecology and Management Studies
- Hormonal and reproductive studies
- Galectins and Cancer Biology
- Autoimmune and Inflammatory Disorders Research
- Hippo pathway signaling and YAP/TAZ
- Cancer Risks and Factors
Guangxi University
2024
Liaocheng People's Hospital
2021-2024
Capital Medical University
2024
Sichuan University
2021-2023
Yueyang Hospital
2006-2023
Shanghai University of Traditional Chinese Medicine
2006-2023
Shandong Tumor Hospital
2020-2022
Shandong First Medical University
2020-2022
First Affiliated Hospital of Xi'an Jiaotong University
2021
State Key Laboratory of Biotherapy
2021
The increasing prevalence of drought events poses a major challenge for upcoming crop production. Melatonin is tiny indolic tonic substance with fascinating regulatory functions in plants. While plants can respond several ways to alleviate stress, the processes underpinning stress sensing and signaling are poorly understood. Hereafter, objectives this investigation were explore putative melatonin regulation sugar metabolism abscisic acid biosynthesis drought-stressed tomato seedlings. (100...
Compared to γ-addition, the α-addition of α-branched β,γ-unsaturated aldehydes faces larger steric hindrance and disrupts π-π conjugation, which might be why very few examples are reported. In this article, a highly diastereo- enantioselective α-regioselective Mannich reaction isatin-derived ketimines with α-, β- or γ-branched aldehydes, generated in situ from Meinwald rearrangement vinyl epoxides, is realized by using chiral N,N'-dioxide/ScIII catalysts. A series α-quaternary allyl...
Highly regio- and enantioselective hydrosilylation of aryl-substituted terminal/internal alkenes with primary silanes was achieved using a chiral La( iii )-bisoxazoline complex.
Lung cancer is a neoplasm with 5-year survival rate of less than 15 % and leading cause death worldwide, despite recent progress in treatment diagnostic methods. stem-like cells (CSCs) are pivotal lung metastasis drug resistance. This study aimed to develop CSCs that stably express stem cell properties through transfection further screen traditional Chinese herbal compounds. adenocarcinoma cells, which include various phenotypic subgroups, normally characterized by high expression levels...
Evidence is required to quantify the population-level effects of endoscopic screening for esophageal squamous cell carcinoma (ESCC). The objective this study was evaluate long-term effectiveness 1-time ESCC in a Chinese rural population.This community-based cohort based on an existing cancer program Feicheng City, China. group consisted all permanent residents aged 40 69 years 17 villages who were screened during 2006 through 2009, and control another 43 not yet covered by program. Residents...
A highly enantioselective formal coupling of β-ketoesters with quinones was accomplished by a chiral bifunctional N-heterocyclic olefin organocatalyst. With as low 1 mol % catalyst loading, number enantioenriched quinone derivatives were afforded in good yields high enantioselectivities and regioselectivities (up to 96% yield, 98% ee, 19:1 rr). Gram-scale synthesis the inhibitory effect several products on viability cancer cells demonstrate potential utility current method.
Abstract Background and aims This study investigated the natural history of esophageal squamous cell carcinoma (ESCC) in rural Chinese. We sought to help provide more data support ESCC screenings. Methods was based on an existing Screening Program Feicheng, China. Esophageal precancerous lesions were identified 1753 cases, diagnosed from cancer screenings 2006 2016. followed up with them through endoscopic screening until October 1, 2017. Pathology results various grades recorded annual...
Abstract Health literacy is closely related to the incidence of major chronic diseases and its behaviors such as cancer-related behaviors. This study explored how cancer health level affects About one two villages from six cities Shandong province were selected sample areas. Professionals conducted face-to-face interviews with participants. Finally, 1200 residents completed 1085 effective questionnaires. Data analysed a cross-sectional survey in 2019, which included cities/counties province,...
Outpatient medical care payment play a pivotal role in the reform of insurance methods. With ongoing reforms China, variety strategies, including capitation and ambulatory patient groups (APG) point method, are being progressively implemented. This study aims to identify appropriate calculation methods for chronic diseases Beijing provide recommendations implementing payments city. We focused on four prevalent diseases—hypertension, diabetes, coronary heart disease, stroke—and analyzed basic...
Abstract Compared to γ‐addition, the α‐addition of α‐branched β,γ‐unsaturated aldehydes faces larger steric hindrance and disrupts π–π conjugation, which might be why very few examples are reported. In this article, a highly diastereo‐ enantioselective α‐regioselective Mannich reaction isatin‐derived ketimines with α‐, β‐ or γ‐branched aldehydes, generated in situ from Meinwald rearrangement vinyl epoxides, is realized by using chiral N , ′‐dioxide/Sc III catalysts. A series α‐quaternary...
Objective To explore the role of calreticulin (CRT) on endoplasmic reticulum stress-induced migration and invasion SMMC-7721 HepG2 hepatocellular carcinoma cells. Methods Endoplasmic stress was established in cells using ER inducer tunicamycin. Expressions binding immunoglobulin protein (BIP), CRT, MMP-9 were examined by Western blot. The ability detected wound healing assay transwell respectively. Using small interfering RNA tunicamycin to observe its effect expression MMP-9,...
Abstract This study aimed to evaluate the impact of cancer-related mortality on life expectancy in Feicheng City. We extracted death records and population data City from 2013 2018 through Center for Disease Control Prevention. The mortality, premature cause-eliminated expectancy, potential years lost (PYLL), average (APYLL), annual change percentage (APC), other indicators cancer were calculated. age-standardized rates calculated using sixth national census (2010). From 2018, rate was...
Abstract Background Central adrenal insufficiency (CAI) is defined as the inability of glands to release sufficient corticosteroids due a series diseases or injuries hypothalamus pituitary. Signs and symptoms CAI are insidious, ambiguous, debilitating. Preceding studies suggest that elderly patients with may present hyponatremia characteristic manifestation, but little mentioned about gastrointestinal (GI) symptoms. Herein we report rare case an male patient radio-chemotherapy history for...
Objective: This study aimed to investigate the association between utilization of Sodium-dependent glucose cotransporters inhibitors (SGLT2i) in real-world settings and kidney outcomes patients with type 2 diabetes (T2D) chronic disease (CKD) southwestern China.Methods: In a retrospective analysis electronic medical records from West China Hospital Sichuan University, T2D CKD were included. Patients divided into two groups, those initiating treatment SGLT2i receiving other glucose-lowering...
Objective To explore a suitable service model of institutional pension by analyzing the validity Combination Medical-Health Care-Psychological that was developed and practiced for long term clinical psychiatric team in Kunming Social Welfare Institute Hospital. Methods 80 elderly inpatients were divided into study group control group. The received service, general medical care mode service. quality life, wellbeing, satisfaction assessed interview with health status questionnaire,...