A5060396794- Healthcare Education and Workforce Issues
- Diverse Approaches in Healthcare and Education Studies
- Cancer Immunotherapy and Biomarkers
- Education and Learning Interventions
- Renal cell carcinoma treatment
- Health and Wellbeing Research
- Healthcare and Venom Research
- Cancer Genomics and Diagnostics
- Multiple and Secondary Primary Cancers
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Long-Term Effects of COVID-19
- Pancreatic and Hepatic Oncology Research
- Liver Disease Diagnosis and Treatment
- Sleep and related disorders
- Pharmacological Effects of Natural Compounds
- Thyroid Disorders and Treatments
- Pharmacy and Medical Practices
- Genomics and Phylogenetic Studies
- Economic and Financial Impacts of Cancer
- Customer Service Quality and Loyalty
- Respiratory Support and Mechanisms
- Bone health and osteoporosis research
- Mindfulness and Compassion Interventions
- Drug-Induced Hepatotoxicity and Protection
- Bone Metabolism and Diseases
University of Pittsburgh
2025
Daejeon University
2023-2025
Semyung University
2018-2025
Emory University
2023-2025
Changwon National University
2022-2025
Kyung Hee University
2024
Korea Institute of Oriental Medicine
2024
University Hospitals Seidman Cancer Center
2024
The University of Texas Southwestern Medical Center
2024
Southwestern Medical Center
2024
The genus Skermanella comprises important soil bacteria that are often associated with the crop rhizospheres, but its physiological traits remain poorly understood. This study characterizes sp. TT6T, isolated from human skin, a focus on metabolic and environmental adaptations. Genome sequencing phylogenomic analyses revealed strain TT6T is most closely related to S. rosea M1T, average nucleotide identity digital DNA-DNA hybridization values of 94.14% (±0.5%) 64.7%, respectively. Comparative...
Non-alcoholic fatty liver disease (NAFLD) is a substantial global health issue owing to its high prevalence and the lack of effective therapies. Fermentation medicinal herbs has always been considered feasible strategy for enhancing efficacy in treating various ailments. This study aimed investigate potential benefits Lactobacillus casei-fermented Amomum xanthioides (LAX) on NAFLD high-fat diet model. HFD-fed C57BL6/j mice were administered with 200 mg/kg LAX or unfermented (AX) 100...
512 Background: Non-clear cell renal carcinoma (nccRCC) includes several molecularly distinct subtypes of carcinoma. Due to their rarity, nccRCC have been understudied, and treatment options are often adapted from clear RCC therapies. Trials investigating immune checkpoint inhibitors (ICIs) demonstrated promising efficacy survival benefits in certain histologies. This report aims present our experience with nccRCC, focusing on patient characteristics, choices, outcomes the era ICIs. Methods:...
603 Background: Multiple studies on various cancer types have investigated concomitant statin, aspirin, and metformin use with immune checkpoint inhibitors. While some found improved OS PFS, others reported no significant effect. In RCC, a retrospective study linked statins PFS. We aimed to evaluate the impact of survival in RCC patients treated ICIs. Methods: A analysis was conducted adult advanced ICIs at Emory Winship Cancer Institute between 2018 2024. Concomitant medication assessed via...
WDJ-S4, a standardized herbal formula, has been prescribed for refractory functional dyspepsia (FD) in Korea, but the detailed mechanisms are lacking. The present study investigates acceleration of gastrointestinal (GI) motility by WDJ-S4 and its potential mechanisms. For five days, (50, 100 200 mg/kg) or mosapride (3 was orally given to BALB/c mice. After 20 h fasting, loperamide (10 mg/kg, i.p.) mice except normal group. To assess gastric emptying intestinal propulsion, 500 μL 0.05% phenol...
The coupling of composite polymer electrolytes with Se/C cathodes was achieved in this study to address the needs modern solid-state batteries, including high-energy density, low temperature operation, cycle stability, and ease manufacture.
Background: Immune checkpoint inhibitors (ICIs) have become the mainstay treatment of metastatic kidney cancer, demonstrating enhanced outcomes and durable responses in select patient subgroups. However, identifying reliable prognostic biomarkers for remains challenging. Objectives: This study aimed to assess correlation between baseline inflammatory markers overall survival (OS), progression-free (PFS), clinical benefit (CB) cancer patients receiving ICIs. CB was defined as achieving stable...
Introduction Systematic collection of diverse adverse events during herbal medicine administration is crucial. The Korea Adverse Event Reporting System (KAERS) compiles spontaneously reported event data for medicinal products including medicines. This study focused on extracting and analyzing specifically related to from the KAERS database. Methods Individual case safety reports (ICSRs) encompassing 84 types products, identified by item codes 2012 2021, were extracted Descriptive statistics...
Based on traditional pharmacological applications and partial in vitro data, Cynanchum atratum (CA) is proposed to act skin whitening. However, its functional evaluation underlying mechanisms have yet be identified. This study aimed examine the anti-melanogenesis activity of CA fraction B (CAFB) UVB-induced hyperpigmentation. Forty C57BL/6j mice were exposed UVB (100 mJ/cm2, five times/week) for eight weeks. After irradiation, CAFB was applied left ear once a day 8 weeks (the right served as...
Although most epidemiological studies have been conducted using a relatively small population or subjects who had medical screenings, the present study aimed to investigate incidence and prevalence of MASLD (formerly NAFLD) in Korea nationwide registry data provided by Health Insurance Review Assessment Service (HIRA).Using records HIRA, we analyzed entire dataset patients with MASL (KCD10-K76.0) MASH (KCD10-K75.8) from 2010 2021 calculated year, age, gender. The rates were analyzing HIRA...
Amomum xanthioides (AX) has been used as an edible herbal medicine to treat digestive system disorders in Asia. Additionally, Lactobacillus casei is a well-known probiotic commonly fermentation processes starter. The current study aimed investigate the potential of casei-fermented (LAX) alleviating metabolic induced by high-fat diet (HFD) mouse model. LAX significantly reduced body and fat weight, outperforming AX, yet without suppressing appetite. also markedly ameliorated excessive lipid...
<title>Abstract</title> Background Breast and prostate are in general, less responsive to Immune checkpoint inhibitors (ICIs). Tumor mutation burden (TMB) has emerged as a predictive biomarker of response ICIs new technologies for evaluating TMB, including liquid biopsy, now available. We aimed investigate the role blood TMB predicting its association with genomics alterations. Methods The clinical cohort included metastatic breast cancer patients treated an ICI following bTMB ≥10 mut/Mb....
본 연구는 청소년들의 치과진료형태에 따른 치과공포감의 영향관계에 대해 규명하여 청소년의 치과진료 시 불안, 공포감을 완화시켜줄 수 있는 방법을 모색하고자 하였다. 조사대상은 경남지역에 재학 중인 청소년을 대상으로 2009년 12월 2일부터 9일까지 8일간 설문조사를 실시하여 420부를 분석에 사용하였다. 연구결과 상관분석을 통한 경험과 공포감의 관계에서 각 구성요소 간 유의한 상관성을 보였고, 회귀분석 결과 전체적인 공포감에는 치과보철 진료경험이, 회피 치과보존 생리적 반응요인 구강악안면 치료자극 진료경험이 영향을 미치는 것으로 나타났다. 이에 향후 치과 의료기관은 청소년들이 치과진료에 대한 막연한 공포나 두려움을 없애고, 정기적인 치과방문을 예방진료 등의 강화로 구강건강증진을 도모하고 건강한 삶을 영위할 있도록 진료형태별 대상별 없앨 매뉴얼 개발 노력이 필요할 생각된다. The purpose of this study was to examine the influential...
본 연구는 중년층을 대상으로 구강건강신념과 구강병 예방행동에 관한 융합적 관계를 분석하였다. U시 일부 중년층 280명을 최종 분석 하였다. 회귀분석의 결과로 볼 때 구강건강신념 중 예방행동의도, 가장 큰 영향을 미치는 요인은 구강건강은 가치 있는 것이라고 느끼는 중요성이었다. 예방행동의도를 매개로 직간접적 알아본 결과, 중요성, 유익성 변인이 영향은 부분매개효과를 가지는 것으로 나타났고, 자기 효능감은 완전매개효과를 나타났다. 연구 이미 구강병에 이환되어 심각성과 장애를 느끼고 중장년층의 구강예방행동을 수행할 수 있도록 하기 위해서는 구강 건강이 전신질환만큼 중요하다는 중요성과 구강건강이 전신건강에 유익하다는 것을 계몽할 중재프로그램 개발이 필요 하겠다. In this study, the amalgamative relationship associated with oral health belief and preventive behavior against disease...
The purposes of this study were to ascertain the morphological characteristics a plantaris tendon (PT) insertion using larger-scale dissection Korean cadavers and classify types PT related calcaneal (CT). A total 108 feet from adult formalin-fixed (34 males, 20 females) dissected. measurements evaluated. Five classified, wherein most common type was Type 1 (39 feet, 63.1%). 2 3 similar, with 16 (14.8%) 15 (13.9%), respectively. 4 (6 5.6%) rarest type, 5 had 25 (23.1%). case an absent noted...
The purpose of this study was to prevent cross-contamination dental hygienists by aerosols. We performed prophylactic scaling on 30 patients who visited the clinic. Microbiologic identification and SEM imaging were confirm number microorganisms in aerosol. Data analysis showed significant difference between two groups using SPSS (ver.21). According results, it confirmed that Gram-positive Gram-negative present aerosol, these identified as microbes causing opportunistic infection human body....
e16542 Background: Current first-line therapy for aRCC involves ICIs, often administered with another ICI or tyrosine-kinase inhibitors (TKIs). While there has been some literature on the association between gender and clinical outcomes in patients aRCC, results are contradictory thus true remains unknown. We explored role of difference undergoing therapies involving ICIs. Methods: conducted a retrospective analysis adult advanced RCC treated ICIs at Emory Winship Cancer Institute 1/1/2018...