Alejandro Cazzulino

ORCID: 0000-0003-4373-615X
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About
Contact & Profiles
Research Areas
  • Spine and Intervertebral Disc Pathology
  • Spinal Fractures and Fixation Techniques
  • Shoulder Injury and Treatment
  • Orthopedic Surgery and Rehabilitation
  • Scoliosis diagnosis and treatment
  • Shoulder and Clavicle Injuries
  • Orthopaedic implants and arthroplasty
  • Neuroscience and Neuropharmacology Research
  • Hip and Femur Fractures
  • Opioid Use Disorder Treatment
  • Trauma Management and Diagnosis
  • Cardiac, Anesthesia and Surgical Outcomes
  • Musculoskeletal pain and rehabilitation
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Receptor Mechanisms and Signaling
  • Pelvic and Acetabular Injuries
  • Radiation Dose and Imaging
  • Diversity and Career in Medicine
  • Memory and Neural Mechanisms
  • Cervical and Thoracic Myelopathy
  • Clinical practice guidelines implementation
  • Hip disorders and treatments
  • Bone fractures and treatments
  • Elbow and Forearm Trauma Treatment
  • Anesthesia and Pain Management

University of California, San Francisco
2020-2023

UCSF Benioff Children's Hospital
2020-2021

Pennsylvania Hospital
2018

University of Pennsylvania
2017-2018

Research Foundation For Mental Hygiene
2015-2017

Columbia University
2015-2017

New York State Psychiatric Institute
2015

Recent studies have focused on the identification and manipulation of memory traces in rodent models. The two main mouse models utilized are either a CreER(T2) /loxP tamoxifen (TAM)- or tetracycline transactivator/tetracycline-response element doxycycline-inducible system. These systems, however, could be improved to label more specific population activated neurons corresponding behavior. Here, we sought identify an selective estrogen receptor (ER) modulator (SERM) which individual trace...

10.1002/hipo.22556 article EN Hippocampus 2015-12-10

Retrospective database study.To analyze the economic and age data concerning primary revision posterolateral fusion (PLF) posterior/transforaminal lumbar interbody (PLIF/TLIF) throughout United States to improve value-based care health utilization.The National Inpatient Sample (NIS) was queried by International Classification of Diseases, Ninth Revision, Clinical Modification codes for patients who underwent or PLF PLIF/TLIF between 2011 2014. Age included number procedures, costs, burden....

10.1177/2192568218790557 article EN cc-by-nc-nd Global Spine Journal 2018-08-15

This cross sectional study describes a "Soft Landing" strategy utilizing hooks for minimizing proximal junctional kyphosis (PJK) and failure (PJF). The technique creates gradual transition from rigid segmental construct to unilateral at the upper instrumented level preservation of soft tissue attachments on contralateral side hooks. Authors devise novel classification system better grading PJK severity.Thirty-nine consecutive adult spinal deformity (ASD) patients single institution received...

10.21037/jss-20-622 article EN Journal of Spine Surgery 2021-03-01

Study Design: Retrospective database study. Objectives: Analysis of economic and demographic data concerning lumbar disc arthroplasty (LDA) throughout the United States to improve value-based care health utilization. Methods: The National Inpatient Sample was queried for patients who underwent primary or revision LDA between 2005 2013. Demographic included total surgeries, costs, length stay, frequency routine discharge. represents a 20% sample discharges from US hospitals weighted provide...

10.1177/2192568217726980 article EN cc-by-nc-nd Global Spine Journal 2017-10-25

Background: Understanding which pediatric patients seek opioid refills is crucial as prescription use in childhood associated with an increased risk of future misuse. Orthopaedic surgeons are optimally positioned to lead the charge addressing epidemic. The aim this study was describe incidence and factors requiring after orthopaedic surgery children. Methods: This retrospective case-control included 1413 aged 0 18 years that underwent at a single tertiary care children’s hospital were...

10.1097/bpo.0000000000001736 article EN Journal of Pediatric Orthopaedics 2020-12-22

» Spondylolysis is defined as a defect of the pars interarticularis, and spondylolisthesis slippage vertebra relative to immediately caudal vertebra. Most cases spondylolysis low-grade can be treated nonoperatively. Depending on patient’s age, nonoperative treatment may include thoracolumbosacral orthosis (TLSO), physical therapy, activity modification. Bracing therapy have been found more effective than modification alone. Patients with dysplastic are at higher risk for progression should...

10.2106/jbjs.rvw.21.00176 article EN JBJS Reviews 2022-03-01

» An unstable slipped capital femoral epiphysis (SCFE) is characterized by the inability to walk and associated with a high risk of osteonecrosis. SCFE less common than stable SCFE; however, demographics are similar in both groups patients SCFE. The diagnosis an history antecedent pain on examination, it confirmed radiographic assessment. Management includes closed reduction, open realignment, which have all been noted lower rates osteonecrosis reported historic reports. All management...

10.2106/jbjs.rvw.20.00268 article EN JBJS Reviews 2021-07-01

Background: Acute sternoclavicular fractures and dislocations (SCFDs) are a rare but important injury in pediatric patients. SCFDs either true dislocations, or more commonly, physeal children. The reduction is advised given the proximity to surrounding vascular structures, some authors advocate for routine fixation rates of redisplacement after closed reduction. purpose current study was provide validated long-term functional outcome data following open surgical SCFDs, as well demographic...

10.1097/bpo.0000000000001691 article EN Journal of Pediatric Orthopaedics 2020-10-02

The prevalence of nonmedical use prescription opioids among American teenagers is staggering. Reducing the quantity postoperative opioid prescriptions can help address this epidemic by decreasing availability opioids. As fourth most common prescribers, orthopaedic surgeons are primed to lead efforts reverse crisis. purpose study was determine patient factors associated with filling after pediatric surgery and recommend potential methods limit excess prescriptions.This retrospective cohort...

10.1097/bpo.0000000000001859 article EN Journal of Pediatric Orthopaedics 2021-05-13

OBJECTIVE The objective of this study was to investigate revision burden and associated demographic economic data for atlantoaxial (AA) fusion procedures in the US. METHODS Patient from National Inpatient Sample (NIS) database primary AA were obtained 1993 2015, 2006 2014 using ICD-9 procedure codes. Data used comparisons between surgeries. rates, hospital costs/charges, length stay (LOS), routine discharge, mortality rates investigated. RESULTS Between 2014, 52,011 patients underwent...

10.3171/2019.11.spine19551 article EN Journal of Neurosurgery Spine 2020-01-24

Acute sternoclavicular fracture-dislocation is associated with high-energy trauma and being increasingly recognized in children1. These injuries are compression of mediastinal structures can be life-threatening1. The management acute includes closed reduction or open surgical stabilization; however, limited success reported reduction2,3. To our knowledge, there no detailed descriptions suture fixation children.Following diagnosis fracture-dislocation, the timing treatment determined...

10.2106/jbjs.st.19.00074 article EN JBJS Essential Surgical Techniques 2020-01-01

Supracondylar, medial epicondyle and lateral condyle fractures are the three most common elbow in pediatric patients. There is a paucity of literature discussing utilization physical therapy following these injuries. The purpose current study was to determine rate after injuries as well factors that may affect need for We retrospectively chart reviewed all were managed at major health system from 2013 2020. This included patients under age 18 years utilized International Classification...

10.1097/bpb.0000000000000929 article EN Journal of Pediatric Orthopaedics B 2021-10-20

Ankle fractures are among the most common physeal in children. When surgical management is warranted, subsequent hardware removal remains controversial. This study was designed to determine rates of patients with ankle and identify risk factors for removal. Procedure data utilized compare procedures removed retained.We conducted a retrospective cohort utilizing from Pediatric Health Information System (PHIS) years 2015 through 2021. We longitudinally followed treated distal tibia procedures....

10.1177/24730114231182396 article EN cc-by-nc Foot & Ankle Orthopaedics 2023-04-01

10.1053/j.semss.2018.07.018 article EN Seminars in Spine Surgery 2018-07-30
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