A5056628328- Neurotransmitter Receptor Influence on Behavior
- Regulation of Appetite and Obesity
- Receptor Mechanisms and Signaling
- Biochemical Analysis and Sensing Techniques
- Neuroscience and Neuropharmacology Research
- Adipose Tissue and Metabolism
- Acoustic Wave Resonator Technologies
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Diet and metabolism studies
- Alcoholism and Thiamine Deficiency
- Nerve injury and regeneration
- Ferroelectric and Piezoelectric Materials
- Pancreatic function and diabetes
- Amino Acid Enzymes and Metabolism
- Surface and Thin Film Phenomena
- Schizophrenia research and treatment
- Magnetic Bearings and Levitation Dynamics
- Polyamine Metabolism and Applications
- Neuropeptides and Animal Physiology
- Ultrasonics and Acoustic Wave Propagation
- Advanced Materials Characterization Techniques
- Engineering Applied Research
- Memory and Neural Mechanisms
- Semiconductor materials and interfaces
Yonsei University
2008-2024
National Center of Neurology and Psychiatry
2014-2018
Kyungbok University
2002-2005
Article AbstractObjective: Many studies have investigated cerebrospinal fluid (CSF) monoamine metabolite levels in depressive disorders. However, their clinical significance is still unclear. We tried to determine whether CSF could be a state-dependent marker for major disorder (MDD) based on analyses stratified by variables relatively large sample.Methods: Subjects were 75 patients with MDD according DSM-IV criteria and 87 healthy controls, matched age, sex, ethnicity (Japanese). They...
Repeated administration of psychostimulants such as cocaine leads to the development behavioral sensitization. Extracellular signal-Regulated Kinase (ERK), an enzyme important for long-term neuronal plasticity, has been implicated in effects these drugs. Although nucleus accumbens (NAcc) is site mediating expression sensitization by drugs abuse, precise role ERK activation this not determined. In study we demonstrate that blockade phosphorylation NAcc a single bilateral microinjections...
Abstract The potential role of the ghrelin receptor, also known as growth hormone secretagogue receptor (GHSR), within nucleus accumbens (NAcc) in regulating drug addiction and feeding has been documented; however, pattern its expression this site remains elusive. In study, we characterized patterns GHSR1a 1b, two subtypes GHSRs, NAcc rat brain by immunohistochemistry. We visually detected GHSR signals, for first time, at protein level which they were mostly expressed neurons including both...
Piezoelectric properties of Pb/sub 1-a/Sr/sub a/(Ni/sub 1/2/W/sub 1/2/)/sub 0.02/(Mn/sub 1/3/Nb/sub 2/3/)/sub b/(Kr/sub x/, Ti/sub y/)/sub 1-0.02-b/O/sub 3/ ceramics added to 0.5 wt% PbO, 0.3 wt%Fe/sub 2/O/sub and 0.25 CeO/sub 2/ were investigated with the variations a=0-0.06, b=0.05-0.07, x=0.49-0.51, y=0.49-0.51. Mechanical quality factor, coercive field Curie temperature decrease Zr/Ti ratio increased by increase tetragonality. According PMN mol%, grain size decreased increased. Moreover,...
Two well-known appetite-regulatory peptides, leptin and cocaine- amphetamine-regulated transcript (CART), are known to be involved in the brain rewarding pathway. However, it is not yet how they interact nucleus accumbens, an important region mediating effects of drugs abuse. Using immunoassay method, we found that a microinjection into accumbens core induces immediate transient increase CART peptide this site, whereas these were inhibited by cocaine. These results expand role accumbal...
Introduction and aims Rat gambling task (rGT) is a recently developed animal model making translational research possible in psychiatric disorders related to decision-making deficits. Methiopropamine (MPA) structural analog methamphetamine temporary controlled substance. Although increasing concerns have been raised regarding MPA's abuse, few sources of information exist its psychopharmacology. Thus, we investigated whether MPA produces any changes the choice preference rGT. Methods Rats...
correlation.Through the hierarchical regression analysis, BDI score had a significant role to increase job stress when surface acting is put into model as well, while BAI and STAXI_S scores did not.Moreover, significantly partial mediation effect on pathway that positively predicts in PW group.In hospital, employees have more emotional labor than those of NPW.In group, stress, depression mediating factor which an important relationship between stress.
In this study, in order to develop the low temperature sintering ceramics for multilayer piezoelectric transformer, PCW-PMN-PZT doped with Li/sub 2/CO/sub 3/, Bi/sub 2/O/sub 3/ and CuO as aids were manufactured, their microstructural, dielectric properties investigated. When only was added, specimens could not be sintered below 980/spl deg/C. However, when addition proved lower of due effect 2/O-Bi/sub liquid phase. added showed higher than those specimens. At 0.2wt% 0.3wt% specimen at...