A5103165339- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Mesenchymal stem cell research
- Neonatal and fetal brain pathology
- Cerebrovascular and Carotid Artery Diseases
- Anesthesia and Neurotoxicity Research
- Tissue Engineering and Regenerative Medicine
- Neurological Disease Mechanisms and Treatments
- Neuroendocrine regulation and behavior
- Pharmacological Effects of Natural Compounds
- Cancer-related molecular mechanisms research
- Pelvic and Acetabular Injuries
- Cardiac and Coronary Surgery Techniques
- Neurogenesis and neuroplasticity mechanisms
- Bone Tissue Engineering Materials
- Medical Imaging and Analysis
- Osteoarthritis Treatment and Mechanisms
- Nerve injury and regeneration
- Renal Diseases and Glomerulopathies
- Evolutionary Psychology and Human Behavior
- Plant biochemistry and biosynthesis
- Glioma Diagnosis and Treatment
Henan Agricultural University
2025
Jiamusi University
2007-2024
Nanjing Drum Tower Hospital
2022-2024
China Automotive Technology and Research Center
2023
Shandong Provincial Hospital
2006-2023
Shandong First Medical University
2023
Cangzhou Central Hospital
2022
Beijing Tsinghua Chang Gung Hospital
2022
Chinese PLA General Hospital
2019-2021
Animal Science Research Institute
2021
The femoral neck system (FNS) may be a valid alternative for treating fractures, but few studies have compared the outcomes between FNS and cannulated cancellous screws. This study aimed to compare clinical efficacy complications of with those inverted screws (ICCS) treatment fractures in adults.This retrospective evaluated patients who underwent or ICCS internal fixation June 2019 January 2020. operative time, intraoperative blood loss, number fluoroscopies, length surgical incision,...
Brain ischemia and reperfusion (I/R) injury may lead to a poor prognosis for ischemic stroke, which could be alleviated by antioxidants with diminished oxidative stress. Betaine is natural nutrient found in beetroot seafood improve cognitive performance the elderly. The present study investigated whether betaine protect brain from I/R injury. Results showed that treatment reduce H2O2-induced cell death PC12 line. Pretreatment reduced infarct volume neuronal apoptosis rat model induced 2-h...
CTP:phosphocholine cytidylyltransferase (CCT) catalyzes a rate-controlling step in the biosynthesis of phosphatidylcholine (PtdCho). Multiple CCT isoforms, CCTalpha, CCTbeta2, and CCTbeta3, are encoded by two genes, Pcyt1a Pcyt1b. The importance CCTalpha mice was investigated deleting exons 5 6 gene using Cre-lox system. Pcyt1a-/- zygotes failed to form blastocysts, did not develop past embryonic day 3.5 (E3.5), implant. In situ hybridization E11.5 embryos showed that is expressed...
Although human umbilical cord mesenchymal stromal cells (hUCMSCs) have been shown to differentiate along an osteogenic lineage in monolayer culture, the potential of these has seldom before investigated three-dimensional scaffolds for bone tissue engineering applications. In this 6-week study, we observed differentiation hUCMSCs on polyglycolic acid (PGA) nonwoven mesh scaffolds, and compared seeding densities use engineering. Cells were seeded into PGA meshes with 5, 25, or 50 x 10(6)...
Vaginal epithelial and smooth muscle cells were isolated expanded successfully. A collagen scaffold loaded with vaginal successfully reconstructed the vagina in a absence pig model.
Human umbilical cord mesenchymal stromal cells (hUCMSCs) have recently shown the capacity to differentiate into multiple cell lineages in all three embryonic germ layers. The osteogenic differentiation of hUCMSCs monolayer culture has been reported, while three-dimensional biomaterials not yet reported for tissue-engineering applications. Thus, aim this study was evaluate feasibility using bone tissue engineering. were cultured poly(L-lactic acid) (PLLA) scaffolds medium (OM) 3 weeks, after...
We identified three novel members of the R2R3-MYB clade anthocyanin regulators in genome purple flowering Petunia inflata S6 wild accession, and we called them ANTHOCYANIN SYNTHESIS REGULATOR (ASR). Two these genes, ASR1 ASR2, are inactivated by two different single base mutations their coding sequence. All genes absent white species P. axillaris N parodii, red exserta, several hybrida lines, including R27 W115. violacea other lines (M1, V30, W59) instead harbor functional copies ASR genes....
ABSTRACT Fusarium crown rot, caused by pseudograminearum ( F. ), poses a significant threat to wheat production in China. Growing evidence suggests that secretes large number of effectors into host, but the biological function these remains poorly understood. Additionally, have not been reported. In this study, we elucidate role Cell Death‐induced Protein 1 (FpCDP1) from secretome , triggering plant immunity inducing cell death, oxidative burst and PTI response. FpCDP1 emerges as conserved...
Rubber elongation factor (REF) and small rubber particle protein (SRPP) are two key factors for natural biosynthesis. To further understand the roles of these proteins in formation, six different genes latex abundant REF or SRPP proteins, including REF138,175,258 SRPP117,204,243, were characterized from Hevea brasiliensis Reyan (RY) 7-33-97. Sequence analysis showed that REFs have a variable long N-terminal, whereas SRPPs C-terminal beyond domain, REF258 has β subunit ATPase its N-terminal....
The present study aimed to investigate the potential roles of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and high-sensitivity C-reactive protein (Hs-CRP) in progression prognosis neonatal hypoxic-ischemic encephalopathy (HIE). observation group comprised 74 neonates with HIE control healthy neonates. serum levels IL-6, TNF-α Hs-CRP were measured patients normal infants. correlations between variances these inflammatory cytokines different clinical gradings prognoses disease...
Purpose: A plenty of studies have demonstrated that the Rho/ROCK pathway is involved in neuronal loss and inhibition axonal regeneration observed Alzheimer's disease (AD). Therefore, we conducted this study to evaluate whether intracranial injection PEG-PEI/ROCK II siRNA (PPRS) would improve cognitive impairments a senescence-accelerated mouse (SAM) model AD. Materials Methods: Five male senescence-resistant inbred strain (SAMR1) mice 15 prone-8 (SAMP8) were divided into following three...
Renal tubular injury contributes to the progression of diabetic nephropathy (DN). This study explored role and mechanisms E3-ubiquitin ligase Parkin in renal DN. We found that expression gradually decreased was inversely associated with IL-6, TGF-β1, GATA4 kidney during over-expression (OE) reduced inflammation, fibrosis, premature senescence epithelial cells (RTECs), improved function while knockout (KO) had opposite effects DN mice. Parkin-OE protein, but not its mRNA transcripts mice high...
Background Type 1 Diabetes Mellitus (T1DM) is one of the most common endocrine disorders childhood and adolescence, showing a rapidly increasing prevalence worldwide. A study indicated that composition oropharyngeal gut microbiota changed in T1DM. However, no studies have yet associated changes between microbiomes intestinal sites, nor flora clinical indicators. In this study, we examined characteristics patients with T1DM compared to healthy children. We identified correlations evaluated...
We aimed to investigate the relationship between increased free fatty acid (FFA) level and early postoperative hypoxemia after coronary artery bypass grafting (CABG) with cardiopulmonary (CPB). Ninety-eight consecutive patients undergoing CABG were enrolled. Early was defined as lowest of ratio arterial oxygen tension (PaO2) inspired fraction (FiO2) ≤ 200 mm Hg within 24 h without pleural effusion pneumothorax. The 26 perioperative factors, serum levels FFA inflammatory cytokines...
More and more samples are obtained from biobanks for biomedical research; however, some of these may undergo thawing before processing. We aim to evaluate the reference gene expression stability in thawed renal cell carcinoma samples. Sixteen matched malignant nonmalignant tissue were each sample was divided into 4 aliquots being snap frozen stored at -80°C. By quantitative real-time polymerase chain reaction, a time-course study conducted on panel 10 most frequently used genes carcinom...
The long-term benefits of interferon-α (IFN-α) treatment in children with chronic hepatitis B (CHB) remain unclear. We conducted a retrospective and real-world study to evaluate the safety clearance rates e antigen (HBeAg) surface (HBsAg) CHB who received IFN-α monotherapy for 72 weeks were 13-year follow-up visit. Participants treated (n = 316) more likely become HBeAg negatve (39.87% vs. 27.37%; p < .05) HBsAg negative (11.08% 3.16%; by end period than untreated participants 95). Treated...