A5077821481- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Cardiac Imaging and Diagnostics
- Aortic Disease and Treatment Approaches
- Cardiac, Anesthesia and Surgical Outcomes
- Pulmonary Hypertension Research and Treatments
- Hemodynamic Monitoring and Therapy
- Cardiac Arrest and Resuscitation
Johannes Gutenberg University Mainz
2020-2023
University Medical Center of the Johannes Gutenberg University Mainz
2020-2023
Leipzig Heart Institute
2015-2017
Leipzig University
2013-2015
Tricuspid regurgitation (TR) is a common and progressive valve disease with significant mortality hospitalization burden. transcatheter edge-to-edge repair provides treatment option for high-risk patients primary secondary TR. The TRILUMINATE trial ([Trial to Evaluate Treatment With Abbott Transcatheter Clip Repair System in Patients Moderate or Greater Regurgitation]; n=85) an international, prospective, single-arm, multicenter study investigate the safety performance of tricuspid TriClip...
Right ventricular dysfunction (RVD), as expressed by right to pulmonary artery coupling, has recently been identified a strong outcome predictor in patients undergoing mitral valve edge-to-edge repair (M-TEER) for secondary regurgitation (MR). The aim of this study was define RVD M-TEER primary MR (PMR) and evaluate its impact on procedural reduction, symptomatic development 2-year all-cause mortality.This multicentre included PMR at nine international centres. cohort divided into derivation...
Aortic valve insufficiency (AI) following left ventricular assist device (LVAD) implantation can potentially limit the success of mechanical circulatory support. We examined prevalence significant AI in new generation LVADs and analysed role aortic opening development these patients.Currently, 102 patients that received a continuous flow LVAD (cf-LVAD) between July 2009 December 2013 are being treated our outpatient clinic with an HeartWare (HVDA) (n = 77) or HeartMate II (HMII, n 25) were...
This study evaluates the impact of untreated preoperative severe mitral valve regurgitation (MR) on outcomes after left ventricular assist device (LVAD) implantation. Of 234 patients who received LVAD therapy in our centre during a 6-year period, we selected those had echocardiographic images good quality and excluded underwent replacement prior to or repair placement. The 128 were divided into 2 groups: Group A with MR (n = 65) B none moderate 63, 28 MR). We evaluated transthoracic...
Objectives: We investigated performance and outcome of the latest-generation balloon-expandable SAPIEN 3 Ultra prosthesis (S3U) compared to established (S3) in a real-world cohort, with focus on paravalvular regurgitation (PVR). Background: PVR is an adverse prognostic indicator short- long-term survival after transcatheter aortic valve replacement (TAVR). The S3U has been designed improve sealing. Methods: enrolled 343 consecutive patients presenting severe native stenosis eligible for...
Transcatheter valvular interventions have undergone significant progress over the last years with novel treatment options in even complex conditions. In conjunction this development, innovative technologies emerged to facilitate a comprehensive and precise imaging for optimal procedural guidance. These novelties include fusion imaging, three-dimensional (3D) intracardiac echocardiography, advanced refined 3D echocardiography rendering tools. The present review provides an overview of these...
Intraprocedural transesophageal echocardiography (TEE) guidance plays an essential role in transcatheter repair therapy of the tricuspid valve (TV). So far, several different imaging concepts are use. However, protocol that fully addresses morphological complexity TV and further offers efficacious workarounds for frequently occurring restrictions is still missing. As a tertiary referral center with large experience more than 250 cases edge-to-edge (TEER) performed at Heart Valve Center...
Introduction: Echocardiographical guiding gains further importance as transcatheter interventions for heart valve diseases advance. In edge-to-edge repair tricuspid regurgitation (TEER-TR), the use of transesophageal echocardiography (TEE) employing biplane imaging with views perpendicular to inflow-outflow-view is suggested. However, robust data on echocardiographical in this setting lacking, well role fluoroscopy settings. Hypothesis: The aim study was evaluate different guiding-approaches...