Man Hu

ORCID: 0000-0003-4409-286X
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About
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Research Areas
  • Medical Imaging Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Head and Neck Cancer Studies
  • Lung Cancer Diagnosis and Treatment
  • Glioma Diagnosis and Treatment
  • Cancer, Hypoxia, and Metabolism
  • Cancer Immunotherapy and Biomarkers
  • Advanced Radiotherapy Techniques
  • Brain Metastases and Treatment
  • Medical Imaging and Pathology Studies
  • Cancer Diagnosis and Treatment
  • Lung Cancer Research Studies
  • Esophageal Cancer Research and Treatment
  • Lung Cancer Treatments and Mutations
  • Salivary Gland Tumors Diagnosis and Treatment
  • Head and Neck Surgical Oncology
  • Radiation Therapy and Dosimetry
  • Radiopharmaceutical Chemistry and Applications
  • Nanoplatforms for cancer theranostics
  • Cancer-related molecular mechanisms research
  • Peptidase Inhibition and Analysis
  • Remote Sensing and Land Use
  • Ear and Head Tumors
  • COVID-19 and healthcare impacts
  • Smart Grid and Power Systems

Shandong Tumor Hospital
2016-2025

Shandong First Medical University
2016-2025

Capital Medical University
2018-2025

Nanchang Institute of Technology
2025

Beijing Children’s Hospital
2022-2025

State Grid Corporation of China (China)
2022-2025

State Key Laboratory of Vehicle NVH and Safety Technology
2025

Academy of Medical Sciences
2015-2024

Shandong University
2011-2024

Institute of Semiconductors
2022

OBJECT Circulating microRNAs (miRNAs) are a new class of highly promising cancer biomarkers. Malignant glioma is one the most devastating and lethal forms intrinsic CNS tumor. Here, authors evaluated serum miRNA 205 (miR-205) levels in patients with glioma. METHODS Sixty-four whom was diagnosed 45 healthy controls were recruited between October 2011 March 2012 randomly assigned to screening cohort or validation cohort. Cohorts other brain tumors, including meningioma (n = 8), primary diffuse...

10.3171/2015.1.jns141577 article EN Journal of neurosurgery 2015-07-31

// Song Xue 1, 2, 3, * , Man Hu 4, Peifeng Li 5 Ji Ma 6 Xie 7 Feifei Teng 4 Yufang Zhu 8 Bingjie Fan Dianbin Mu 9 and Jinming Yu 1 School of Medicine Life Sciences, University Jinan-Shandong Academy Medical Jinan, Shandong, China 2 Shandong 3 Department Radiation Oncology, Province Key Laboratory Cancer Hospital Institute, Affiliated to University, Pathology, General Jinan Military Command, Medicine, Provincial Neurosurgery, These authors contributed equally this work Correspondence to: Mu,...

10.18632/oncotarget.17922 article EN Oncotarget 2017-05-17

Radiotherapy is inevitably accompanied by some degree of radiation resistance, which leads to local recurrence and even therapeutic failure. To overcome this limitation, herein, we report the room-temperature synthesis an iodine- ferrocene-loaded covalent organic framework (COF) nanozyme, termed TADI-COF-Fc, for enhancement radiotherapeutic efficacy in treatment radioresistant esophageal cancer. The iodine atoms on COF not only exerted a direct effect radiotherapy, increasing its X-ray...

10.1021/acsnano.3c06967 article EN ACS Nano 2023-10-06

Multidrug resistance in pancreatic cancer poses a significant challenge clinical treatment. Bufalin (BA), compound found secretions from the glands of toads, may help overcome this problem. However, severe cardiotoxicity thus far has hindered its application. Hence, present study aimed to develop cell membrane-camouflaged and BA-loaded polylactic-co-glycolic acid nanoparticle (CBAP) assess potential counter chemoresistance cancer.The toxicity CBAP was evaluated by electrocardiogram, body...

10.1016/j.drup.2023.101005 article EN cc-by-nc-nd Drug Resistance Updates 2023-08-21

The study aimed to explore the specific function and mechanism of miR-144-3p in glioblastoma (GBM) cells with different phosphatase tensin homolog (PTEN) phenotypes. We demonstrated that level was significantly down-regulated glioma compared non-neoplastic brain tissues, decreased ascending grades. loss effectively predicted overall survival patients. Interestingly, expression MET up-regulated inversely associated tissues. Next, we certified specifically bound 3'-untranslated region (3' UTR)...

10.1111/jnc.13272 article EN Journal of Neurochemistry 2015-08-06

The details of the immunological microenvironment and its clinical implications for pancreatic cancer are still unclear. In this study, we obtained data from public databases, such as Gene Expression Omnibus, Cancer Genome Atlas Program, International Consortium Data Portal, ArrayExpress Warehouse, cBioPortal Genomics. We used these to evaluate pattern immune cells infiltration in ductal adenocarcinoma (PDAC) tissues. observed that levels M0 macrophages activated dendritic tumor tissues were...

10.1016/j.jare.2020.03.009 article EN cc-by-nc-nd Journal of Advanced Research 2020-03-30

Since there is high local failure and poor survival for unresectable esophageal squamous cell carcinoma (ESCC), the necessity of elective node irradiation controversial. The purpose this study was to investigate patterns in patients with locally advanced ESCC receiving involved-field (IFI).A retrospective preformed on clinical records ESCC, who have received IFI concurrent chemotherapy between January 2003 2009. Comparing target volume first sites failure, were defined as in-field,...

10.1186/1748-717x-9-64 article EN cc-by Radiation Oncology 2014-02-26

(18)F-fluoroerythronitroimidazole ((18)F-FETNIM) PET/CT allows a noninvasive assessment of tumor hypoxia. The purpose this study was to evaluate and simplicity parameter for quantization (18)F-FETNIM uptake with expectations predict survival in non-small cell lung cancer surgical patients investigate the relationship between molecular markers related hypoxia, glucose metabolism, angiogenesis.Thirty-two biopsy-proven treatment were enrolled from March 2007 February 2011. All had studies...

10.1097/rlu.0b013e318279fd3d article EN Clinical Nuclear Medicine 2013-06-22

Purpose: To evaluate the efficacy of dual-time-point F-18 fluorodeoxyglucose positron emission tomography (FDG PET)/ computed (CT) for mediastinal nodal staging in non-small-cell lung cancer patients with comorbidity. Materials and Methods: Fifty-three pathologically proven pulmonary comorbidity 49 as controlled group without were enrolled. PET/CT was performed at 1-hour (whole body) post-FDG injection repeated 2 hours (thoracic) after injection. All received radical surgery system lymph...

10.1097/rlu.0b013e3182173810 article EN Clinical Nuclear Medicine 2011-05-05

10.1109/tcsvt.2025.3538770 article EN IEEE Transactions on Circuits and Systems for Video Technology 2025-01-01

Abstract Background Juvenile xanthogranuloma (JXG) is a rare disorder that belongs to the broad group of non‐Langerhans cell histiocytosis. It characterized by one or more nodules with predilection sites on head, neck, and trunk, lesions may be several millimeters in diameter. These are reddish yellowish benign papules usually resolve spontaneously. The involvement organs other than skin termed systemic juvenile (SJXG). eye most frequent extracutaneous location JXG. Case presentation We...

10.1002/msp2.70003 article EN cc-by Malignancy Spectrum 2025-03-27

Bone metastasis is a common and serious complication in lung cancer patients, leading to severe pain, pathological fractures, reduced quality of life. Early prediction bone can enable timely interventions improve patient outcomes. In this study, we developed multimodal Swin Transformer-based deep learning model for predicting risk patients by integrating CT imaging data. A total 215 with confirmed diagnoses, including those without metastasis, were included. The was designed process...

10.1016/j.jbo.2025.100681 article EN cc-by-nc-nd Journal of bone oncology 2025-04-17

Three-dimensional (3D) printing represents a pivotal technological advancement in dental prosthetics, fundamentally transforming the fabrication of provisional crowns and bridges through innovative vat photopolymerization methodologies, specifically stereolithography (SLA) digital light processing (DLP). This comprehensive scholarly review critically examines landscape 3D-printed resin-based bridges, systematically analyzing their material performance, clinical applications, prospective...

10.3390/ma18102202 article EN Materials 2025-05-10
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