It has been suggested that high altitude can reduce the infectivity and case fatality rate of COVID-19. We investigated relationship between COVID-19 pandemic in Colombia. Epidemiological data included number positive cases, deaths, In particular, we analyzed from 70 cities with altitudes 1 3,180 m. Correlations linear regression models adjusted to population density were performed examine contribution epidemiological variables. The was negatively correlated cities. incidence cases deaths...

Contamination of Cartagena Bay, Colombia with heavy metals such as mercury (Hg) and cadmium (Cd) presents a major environmental public health concern, particularly for human communities residing on nearby islands coastal areas. These populations face enhanced exposure risks owing to their traditional fishing practices continuous interactions polluted marine environments. This study aimed evaluate the genotoxic effects Hg Cd in from island zone district, Bolívar. Ninety-four individuals four...

BackgroundCytokine dysregulation in COVID-19 patients aged over 60 has been associated to adverse outcomes. While serum levels have studied, cellular expression, particularly Afro-Colombians, remains understudied. This research aims describe cytokine expression peripheral blood leukocytes and its association with outcomes at Cartagena's referral hospital.MethodsA cohort study was conducted, encompassing severe critical cases of between November 2021 February 2022. At baseline, the level...

Background: Mycobacterium leprae was considered the only causal agent of leprosy until lepromatosis identified' which it has been suggested greater pathogenicity and is linked to diffuse lepromatous (DLL) Lucio's phenomenon (LPh). Our objective identify spp. in an endemic area Colombia. Methods: The study included cases with a diagnosis by clinical histopathological analysis. DNA extraction two specific rounds semi-nested polymerase chain reaction (PCR) were performed paraffin biopsies skin...

The influence of climate on the epidemiology dengue has scarcely been studied in Cartagena.

The newborn screening program in Ecuador has been operating since 2011 under the responsibility of Ministry Health. This is centralized and diagnoses four diseases: congenital hypothyroidism, phenylketonuria, galactosemia, adrenal hyperplasia. study aimed to assess geographical distribution cases Ecuador. Spatial analysis techniques were applied using records National Newborn Screening Program with a disease confirmed from January 2012 December 2019. Morbidity rates per 100,000 calculated by...

Mosquito studies are important for understanding their role in the transmission of pathogens including arboviruses, parasites, and protozoa. This study characterized prevalence Culicidae fauna rural peri-urban areas with human populations Colombian Caribbean region to establish risk mosquito-borne pathogens. From 2016 2017, adult mosquitos were collected Turbaco (Bolívar), Sabanalarga (Atlántico) Pueblo Bello (Cesar). The collections forest fragments using CDC, Shannon, bait traps. In areas,...

<ns3:p>Background Contamination of Cartagena Bay, Colombia with heavy metals such as mercury (Hg) and cadmium (Cd) presents a major environmental public health concern, particularly for human communities residing on nearby islands coastal areas. These populations face enhanced exposure risks owing to their traditional fishing practices continuous interactions polluted marine environments. This study aimed evaluate the genotoxic effects Hg Cd in from island zone district, Bolívar. Methods...

<ns3:p>Background Contamination of Cartagena Bay, Colombia with heavy metals such as mercury (Hg) and cadmium (Cd) presents a major environmental public health concern, particularly for human communities residing on nearby islands coastal areas. These populations face enhanced exposure risks owing to their traditional fishing practices continuous interactions polluted marine environments. This study aimed evaluate the genotoxic effects Hg Cd in from island zone district, Bolívar. Methods...

In Colombia, human leishmaniasis is endemic in rural areas, with increasing reports of outbreaks and cases urban areas. Cartagena, an city the Colombian Caribbean a wildland-urban interface, faced its first local between 2011 2015. Despite reports, visceral (VL) remains neglected understudied almost devoid active surveillance. Here we report epidemiological molecular surveillance Leishmania species humans, domestic dogs, sandflies at wildland interface two poverty-stricken neighborhoods...

Background/Objectives: This study aimed to investigate the association of IL-6 with steatotic liver disease (SLD) and fibrosis (LF) in rheumatoid arthritis (RA) patients at a rheumatology center Cartagena de Indias, Colombia. Methods: was cross-sectional that included RA non-RA cases. The level cellular expression interleukin 6 (IL-6) evaluated by flow cytometry peripheral blood leukocytes, presence SLD LF detected elastosonography. main outcome establish between levels development LF....

Abstract Cleidocranial dysplasia is a rare disease with an autosomal‐dominant inheritance that mainly affects the bones of axial skeleton. In this report, we discuss clinical and radiological signs case series comprising three sisters son one sisters, all suspected bone dysplasia.

<ns3:p><ns3:bold>Background: </ns3:bold>The giant African snail, <ns3:italic>Achatina fulica</ns3:italic>, is an invasive species recognized for being a serious agricultural pest and intermediary vector diverse parasites that cause diseases in humans. The knowledge of the state snail populations urban areas great ecological public health importance. Therefore, our objective was to characterize status present city Cartagena, Colombia, including assessment nematode specimens.</ns3:p><ns3:p>...

The epidemiology of the coronavirus disease (COVID-19) has been scarcely described in individuals under 18 years old, particularly during first months pandemic. study aimed to describe COVID-19 Colombian department Bolívar from March 2020 April 2021 among years. Furthermore, we explored whether use data generated by a reference laboratory captures departmental epidemiology. Two information sources were used; national surveillance system and laboratory. In using population-based ecological...

<ns3:p><ns3:bold>Background: </ns3:bold>The giant African snail, <ns3:italic>Achatina fulica</ns3:italic>, is an invasive species recognized for being a serious agricultural pest and intermediary vector diverse parasites that cause diseases in humans. The knowledge of the state snail populations urban areas great ecological public health importance. Therefore, our objective was to characterize status present city Cartagena, Colombia, including assessment nematode specimens.</ns3:p><ns3:p>...

Leptospirosis is an acute febrile disease that mainly affects developing countries with tropical climates. The complexity and magnitude of this attributed to socioeconomic, climatic, environmental conditions. In study, in a 10-year period from 2008 2017, the relationship between human leptospirosis cases climatic factors Cartagena de Indias, Colombia were evaluated. Monthly cases, variables, macroclimatic phenomena (El Niño La Niña) obtained public datasets. Local included temperature...

We are living in times when a viral pandemic has stopped normal life much of the world. The new agent named Coronavirus 2 Severe Acute Respiratory Syndrome (SARS-CoV-2), was found to be cause so-called Disease 2019 (COVID-19). This coronavirus is closely related other emerging zoonotic coronaviruses, such as etiological (SARS-CoV) and Middle East (MERS-CoV), which can disease severe humans (1). Early symptoms most COVID-19 patients include fever, dyspnea, cough, sore throat, progress...

Cystic fibrosis (CF) is a serious autosomal recessive disorder. Early diagnosis, comorbidity prevention, and control are cornerstones for quality life improving expectancy. In Colombian Caribbean, where there genetically admixed population, CF an orphan disease affecting children adults, it remains challenging issue to be addressed carefully. This work describes the genetic, clinical, paraclinical profiles of patients from Cartagena de Indias, Colombia.Thirty-six were included in study. The...