A5082970241- Mosquito-borne diseases and control
- Porphyrin and Phthalocyanine Chemistry
- Malaria Research and Control
- Photodynamic Therapy Research Studies
- Viral Infections and Vectors
- Cardiac, Anesthesia and Surgical Outcomes
- Insect Pest Control Strategies
- Diet and metabolism studies
- Public Health and Environmental Issues
- SARS-CoV-2 and COVID-19 Research
- Research on Leishmaniasis Studies
- Heavy Metal Exposure and Toxicity
- Respiratory viral infections research
- Intensive Care Unit Cognitive Disorders
- Porphyrin Metabolism and Disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Tuberculosis Research and Epidemiology
- Leprosy Research and Treatment
- COVID-19 Clinical Research Studies
- Anesthesia and Sedative Agents
- Effects and risks of endocrine disrupting chemicals
- History of Medicine Studies
- Bioactive Compounds and Antitumor Agents
- Bone Metabolism and Diseases
- Animal Ecology and Behavior Studies
University of Cartagena
2016-2025
Institute of Agrifood Research and Technology
2021
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria
2021
United States Naval Medical Research Unit SOUTH
2021
Policlinico S.Orsola-Malpighi
2019
University of Bologna
2019
Northwestern University
2019
Cornell University
2019
Contamination of Cartagena Bay, Colombia with heavy metals such as mercury (Hg) and cadmium (Cd) presents a major environmental public health concern, particularly for human communities residing on nearby islands coastal areas. These populations face enhanced exposure risks owing to their traditional fishing practices continuous interactions polluted marine environments. This study aimed evaluate the genotoxic effects Hg Cd in from island zone district, Bolívar. Ninety-four individuals four...
ABSTRACT Respiratory viruses represent a significant public health threat. There is the need for robust and coordinated surveillance to guide global responses. Established in 2012, Global Influenza Hospital Surveillance Network (GIHSN) addresses this by collecting clinical virological data on persons with acute respiratory illnesses across network of hospitals worldwide. GIHSN utilizes standardized patient enrolment collection protocol its study sites. It leverages pre‐existing national...
In this study, a family of porphyrins based on 5,10,15,20-Tetrakis(4-ethylphenyl)porphyrin (1, Ph) and six metallo-derivatives (Zn2+(2, Ph-Zn), Sn4+(3, Ph-Sn), Mn2+ (4, Ph-Mn), Ni2+ (5, Ph-Ni), Al3+ (6, Ph-Al), V3+ (7, Ph-V)) were tested as photosensitizers for photodynamic therapy against Leishmania braziliensis panamensis. The singlet oxygen quantum yield value (ΦΔ) (1–7) was measured using 1,3-diphenylisobenzofuran (DPBF) trapping agent 5,10,15,20-(tetraphenyl)-porphyrin (H2TPP) reference...
Water-related diseases are closely linked with drinking water, sanitation, and hygiene (WASH) indicators, socioeconomic status, education level, or dwelling's conditions. Developing countries exhibit a particular vulnerability to these diseases, especially rural areas urban slums. This study assessed features, WASH water-related in two of the Colombian Caribbean coast. Most this population did not finish basic (72.3%,
We describe an Oropouche orthobunyavirus infection in a women 28 years of age Colombia. confirmed the diagnosis by viral isolation, quantitative reverse transcription PCR, and phylogenetic analysis small, medium, large genomic segments. The virus is related to strain isolated Ecuador 2016.
Objective. To estimate anthropometric parameters’ (APs) cut-off points and association for metabolic syndrome (MetS). Materials methods. A cross-sectional study was carried out with a total of 434 adult women from Cartagena de Indias, Colombia, in 2012. APs measured were waist circumference (WC), body mass index (BMI), adiposity (BAI), waist-hip ratio (WHR) waist-height (WHtR). Cut-off estimated by receiver operating characteristic curve (ROC). Logistic regression applied to possible...
Background: The caveolin 1 (CAV1) gene has been associated with metabolic traits in animal models and human cohorts. Recently, a prevalent variant CAV1 found to be related syndrome Hispanics living North America. Since represent an admixed population at high risk for cardiovascular diseases, this study Latin American similar genetic background was assessed. Objective: To analyze association between population. Methods: A cross-sectional carried out adults from the Colombian Caribbean Coast,...
Aedes aegypti is the main vector of dengue, chikungunya, and Zika viruses, which are great public health importance in Colombia. control strategies Colombia rely heavily on use organophosphate pyrethroid insecticides, providing constant selection pressure emergence resistant populations. In recent years, insecticide has increased due to incidence dengue introductions chikungunya Zika. present study, resistance was studied across six populations Ae. from Caribbean coast Susceptibility...
BackgroundCytokine dysregulation in COVID-19 patients aged over 60 has been associated to adverse outcomes. While serum levels have studied, cellular expression, particularly Afro-Colombians, remains understudied. This research aims describe cytokine expression peripheral blood leukocytes and its association with outcomes at Cartagena's referral hospital.MethodsA cohort study was conducted, encompassing severe critical cases of between November 2021 February 2022. At baseline, the level...
La sedación es un conjunto de acciones dirigidas a lograr que paciente se encuentre tranquilo, cómodo, libre dolor o malos recuerdos mientras realiza procedimiento diagnóstico terapéutico. Dado las técnicas anestésicas regionales empleadas en la práctica clínica habitual son procedimientos relativamente traumáticos y dolorosos, han asociado sedación, para hacer este tipo intervenciones más confortables el fácil colaboración del mismo. Determinar eficacia 3 pautas pacientes van ser sometidos...
Adiponectin is a hormone secreted by adipose tissue. It regulates glycolysis and lipolysis involved in the pathophysiology of diabetes related disorders. Its activity mainly mediated transmembrane receptors AdipoR1 AdipoR2, which are encoded ADIPOR1 (1q32.1) ADIPOR2 (12p13.33) genes, respectively. In genetic association studies, single nucleotide polymorphisms (SNPs) or near these genes have been associated with metabolic alterations. However, relationships still controversial.The aim this...
Introduction. Dengue is a public health problem in La Guajira region. Control has focused on the vector using insecticides, including organophosphates. Objective. To evaluate state of susceptibility to organophosphates insecticides fifteen Aedes aegypti (L.) populations Guajira, Colombia. Materials and methods. We collected samples third-instar larvae adult mosquitoes Ae. municipalities Albania, Barrancas, Dibulla, Distracción, El Molino, Fonseca, Hatonuevo, Jagua del Pilar, Maicao, Manaure,...
Metabolic Syndrome (MS) is a cluster of alterations associated to high risk cardiovascular diseases and diabetes mellitus. Although public health issue, little has been studied about its impact in the anesthetic-surgical scene. To analyze correlation level between MS perioperative complications, patients under programmed surgery with general anesthesia technique Cartagena, Colombia. A case control study was designed, where 300 were enrolled: 150 cases controls. Socio-demographic,...
Dengue, chikungunya, and Zika are of great concern to the public health Colombia. One main control strategies for these diseases is application insecticides directed at Aedes aegypti vector. However, insecticide resistance has been increasingly recorded in country, making measures difficult. Here, we evaluated profiles pyrethroids populations Ae. from La Guajira, The frequency (diagnostic dose, DD) intensity (2×, 5×, 10× permethrin, deltamethrin, lambda-cyhalothrin were determined 15...
El síndrome metabólico es un conjunto de alteraciones asociadas a alto riesgo enfermedades cardiovasculares. Aunque representa problema salud pública, poco se conoce su impacto en situaciones como la anestésica-quirúrgica. Analizar correlación entre y complicaciones perioperatorias pacientes cirugía programada con anestesia general Cartagena, Colombia. Se diseñó estudio casos controles, 300 pacientes: 150 controles. registraron variables sociodemográficas, hemodinámicas, respiratorias,...
Caveolin 1 gene (CAV1) has been associated with insulin resistance, metabolic syndrome and hypertension in humans. Also, it related to high serum triglycerides rodents, however there is little evidence of this relation humans.To describe frequencies common variations CAV1 adults triglycerides.A case-control study was carried out from Colombian Caribbean Coast. A whole blood sample employed measure concentrations triglycerides, glucose, total cholesterol HDLc. Six Single Nucleotide...
Abstract The use of insecticides for the control Aedes aegypti (L.) (Diptera: Culicidae) in Colombia has indirectly influenced susceptibility status Culex quinquefasciatus Say populations. We evaluated pyrethroid two populations Cx. Atlantico Department and its possible resistance mechanism (kdr mutation). Bottle bioassays were performed permethrin, deltamethrin, λ-cyhalothrin female mosquitoes quinquefasciatus. ratios (RRs) KC50 LC50 each insecticide field examined determined, using...
Background: Mycobacterium leprae was considered the only causal agent of leprosy until lepromatosis identified' which it has been suggested greater pathogenicity and is linked to diffuse lepromatous (DLL) Lucio's phenomenon (LPh). Our objective identify spp. in an endemic area Colombia. Methods: The study included cases with a diagnosis by clinical histopathological analysis. DNA extraction two specific rounds semi-nested polymerase chain reaction (PCR) were performed paraffin biopsies skin...
The influence of climate on the epidemiology dengue has scarcely been studied in Cartagena.