A5014086898- Respiratory viral infections research
- Influenza Virus Research Studies
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Pneumonia and Respiratory Infections
- HIV/AIDS Research and Interventions
- Viral gastroenteritis research and epidemiology
- HIV Research and Treatment
- Sex work and related issues
- HIV/AIDS drug development and treatment
- Viral Infections and Immunology Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Vector-borne infectious diseases
- COVID-19 epidemiological studies
- Animal Disease Management and Epidemiology
- Smoking Behavior and Cessation
- Malaria Research and Control
- HIV/AIDS oral health manifestations
- Viral Infections and Outbreaks Research
- Tuberculosis Research and Epidemiology
- Virology and Viral Diseases
- Trypanosoma species research and implications
- Yersinia bacterium, plague, ectoparasites research
- HIV, Drug Use, Sexual Risk
- Rabies epidemiology and control
National University of San Marcos
2016-2025
Universidad Internacional
2022
Universidad San Marcos
2022
Instituto de Medicina Tropical
2019
Daniel Alcides Carrión National University
2016
United States Naval Medical Research Unit SOUTH
2005-2015
Dirección Regional de Salud del Callao
2015
Johns Hopkins University
2014
Naval Medical Research Command
2005-2012
Centro Nacional de Enfermedades Tropicales
2012
Background Arthropod-borne viruses (arboviruses) are among the most common agents of human febrile illness worldwide and important emerging pathogens, causing multiple notable epidemics disease over recent decades. Despite public health relevance, little is know about geographic distribution, relative impact, risk factors for arbovirus infection in many regions world. Our objectives were to describe arboviruses associated with acute undifferentiated participating clinics four countries South...
In May of 2010, two communities (Truenococha and Santa Marta) reported to be at risk vampire bat depredation were surveyed in the Province Datem del Marañón Loreto Department Perú. Risk factors for exposure included age less than or equal 25 years owning animals that had been bitten by bats. Rabies virus neutralizing antibodies (rVNAs) detected 11% (7 63) human sera tested. ribonucleoprotein (RNP) immunoglobulin G (IgG) three individuals, whom also seropositive rVNA. RNP IgM one respondent...
Background Disease caused by the dengue virus (DENV) is a significant cause of morbidity throughout world. Although prior research has focused on association specific DENV serotypes (DENV-1, DENV-2, DENV-3, and DENV-4) with development severe outcomes such as hemorrhagic fever shock syndrome, relatively little work correlated other clinical manifestations particular serotype. The goal this study was to estimate compare prevalence non-hemorrhagic infection Methodology Principal Findings...
We present a preliminary analysis of 1,771 confirmed cases influenza A(H1N1)v reported in Peru by 17 July including the frequency clinical characteristics, spatial and age distribution estimate transmission potential. Age-specific was highest among school children young adults, with lowest seniors, pattern that is consistent reports from other countries. Estimates reproduction number lie range 1.2 to 1.7, which broadly previous estimates for this pandemic regions. Validation these will be...
Background Acute respiratory illnesses and influenza-like (ILI) are a significant source of morbidity mortality worldwide. Despite the public health importance, little is known about etiology these acute in many regions South America. In 2006, Peruvian Ministry Health (MoH) US Naval Medical Research Center Detachment (NMRCD) initiated collaboration to characterize viral agents associated with ILI describe clinical epidemiological presentation affected population. Methodology/Principal...
Background Dengue is one of the most aggressively expanding mosquito-transmitted viruses. The human burden approaches 400 million infections annually. Complex transmission dynamics pose challenges for predicting location, timing, and magnitude risk; thus, models are needed to guide prevention strategies policy development locally globally. Weather regulates transmission-potential via its effects on vector dynamics. An important gap in understanding risk roadblock model an empirical...
BackgroundWe evaluated associations between human immunodeficiency virus (HIV) infection, herpes simplex type 2 (HSV-2) and syphilis among men who have sex with (MSM) in Peru MethodsA surveillance survey of 3280 MSM was conducted; sexual behavior assessed a structured computer-assisted self-interview, serum antibody testing performed for HIV, HSV-2, Treponema pallidum ResultsHIV, seroprevalences 13.9%, 46.3%, 13.4% were detected, respectively. HSV-2 seroprevalence twice as high HIV-infected...
HIV cross-sectional studies were conducted among high-risk populations in 9 countries of South America. Enzyme-linked immunosorbent assay screening and Western blot confirmatory testing performed, env heteroduplex mobility genotyping DNA sequencing performed on a subset HIV-positive subjects. prevalences highest men who have sex with (MSM; 2.0%-27.8%) found to be associated multiple partners, noninjection drug use (non-IDU), sexually transmitted infections (STIs). By comparison, much lower...
Abstract Background The Global Influenza Hospital Surveillance Network (GIHSN) was established in 2012 to conduct coordinated worldwide influenza surveillance. In this study, we describe underlying comorbidities, symptoms, and outcomes patients hospitalized with influenza. Methods Between November 2018 October 2019, GIHSN included 19 sites 18 countries using a standardized surveillance protocol. infection laboratory-confirmed reverse-transcription polymerase chain reaction. A multivariate...
ABSTRACT Respiratory viruses represent a significant public health threat. There is the need for robust and coordinated surveillance to guide global responses. Established in 2012, Global Influenza Hospital Surveillance Network (GIHSN) addresses this by collecting clinical virological data on persons with acute respiratory illnesses across network of hospitals worldwide. GIHSN utilizes standardized patient enrolment collection protocol its study sites. It leverages pre‐existing national...
We conducted a randomized, double-blind, phase III yellow fever (YF) vaccine trial among 1,107 healthy children in Sullana northern Peru. The safety and efficacy (by measurement of geometric mean neutralizing antibody titer responses) were determined for two YF vaccines, ARILVAX (n = 738) YF-VAX(R) 369). Serocon-version rates higher (94.9%) than YF-VAX (90.6%) recipients. two-sided 95% confidence interval (YF-VAX-ARILVAX) was (-12.8% to -2.5%), indicating that the seroconversion rate Arilvax...
Abstract After a human rabies outbreak in southeastern Peru, we collected bats to estimate the prevalence of various species. Among 165 from 6 genera and 10 species, 10.3% were antibody positive; was similar vampire nonvampire bats. Thus, may also be source for Peru.
Background Highly refined surveillance data on the 2009 A/H1N1 influenza pandemic are crucial to quantify spatial and temporal characteristics of pandemic. There is little information about spatial-temporal dynamics in South America. Here we provide a quantitative description age-specific morbidity patterns across administrative areas Peru. Methods We used daily cases influenza-like-illness, tests for virus infections, laboratory-confirmed reported epidemiological system Peru's Ministry...
Dengue virus (DENV) infection causes an acute febrile illness generally considered to result in either complete recovery or death. Some reviews describe persistent symptoms after the phase, although empirical data supporting this phenomenon is scarce. We evaluated symptom persistence DENV-infected and DENV-negative (controls) individuals from Peru. Self-reported solicited were at a follow-up visit, occurring 10–60 days onset. Rate of least one was 7.7% 10.5% for DENV infected control...
This paper presents a description of Peru’s experience with pandemic H1N1 influenza 2009. It is based on data from four main surveillance systems: a) ongoing sentinel influenza-like illness cases virological and other respiratory viruses; b) severe acute infections associated deaths; c) in children under the age five years pneumonia all groups; d) case cluster surveillance. On 9 May 2009, first confirmed Peru was diagnosed Peruvian citizen returning New York illness. By July, community...
Despite the disease burden imposed by respiratory diseases on children in Central America, there is a paucity of data describing etiologic agents disease.To analyze viral associated with influenza-like illness (ILI) participants reporting to one outpatient health center, pediatric hospital, and three general hospitals El Salvador, Honduras, Nicaragua Material &Between August 2006 April 2009, pharyngeal swabs were collected from outpatients inpatients. Patient specimens inoculated onto...
Background Currently, there is a paucity of data regarding human adenovirus (HAdv) circulation in Andean regions South America. To address this shortcoming, we report the clinical, phylogenetic, and epidemiologic characteristics HAdv respiratory tract infection from large sentinel surveillance study conducted among adults children Peru. Methods/Principal Findings Oropharyngeal swabs were collected participants visiting any 38 participating health centers, viral pathogens identified by...
Abstract Background The Global Influenza Hospital Surveillance Network (GIHSN) has since 2012 provided patient-level data on severe influenza-like-illnesses from >100 participating clinical sites worldwide based a core protocol and consistent case definitions. Methods We used multivariable logistic regression to assess the risk of intensive care unit admission, mechanical ventilation, in-hospital death among hospitalized patients with influenza explored role covariates country income...
HIV subtypes B, F, and BF recombinants have been previously reported in South America. This report describes the presence of HIV-1 subtype C infection countries Argentina, Uruguay, Paraguay dating back to at least 1999. Surveillance for uncommon non-B/non-F viruses circulating America has conducted samples obtained from nine countries. Peripheral blood mononuclear cells (PBMC), dried filter paper (FP), fresh (FB) were collected HIV-positive patients Ecuador, Colombia, Venezuela, Peru, Chile,...
Background We describe the temporal variation in viral agents detected influenza like illness (ILI) patients before and after appearance of ongoing pandemic A (H1N1) (pH1N1) Peru between 4-January 13-July 2009. Methods At health centers, one oropharyngeal swab was obtained for isolation. From epidemiological week (EW) 1 to 18, at US Naval Medical Research Center Detachment (NMRCD) Lima, specimens were inoculated into four cell lines virus In addition, from EW 19 28, also analyzed by real...