A5108051048- Nail Diseases and Treatments
- melanin and skin pigmentation
- Autoimmune Bullous Skin Diseases
- Cutaneous lymphoproliferative disorders research
- Dermatologic Treatments and Research
- Skin Diseases and Diabetes
- Cutaneous Melanoma Detection and Management
- Acne and Rosacea Treatments and Effects
- Genetic and rare skin diseases.
- Nonmelanoma Skin Cancer Studies
- Cancer and Skin Lesions
- Drug-Induced Adverse Reactions
- Herpesvirus Infections and Treatments
- HIV Research and Treatment
- Leprosy Research and Treatment
- HIV/AIDS Research and Interventions
- Skin and Cellular Biology Research
- Mycobacterium research and diagnosis
- T-cell and Retrovirus Studies
- Skin Protection and Aging
- Autoimmune and Inflammatory Disorders
- Fungal Infections and Studies
- Eosinophilic Disorders and Syndromes
- Systemic Lupus Erythematosus Research
- Mast cells and histamine
Universidad de Antioquia
1993-2022
Asociación Colombiana de Dermatología y Cirugía Dermatológica
2022
Universidad Pontificia Bolivariana
2022
Fundación Santa Fe de Bogotá
2022
Universidad de Los Andes
2022
Fundación Universitaria Juan N. Corpas
2022
Weill Cornell Medicine
2020-2021
Cornell University
2020-2021
Universidad Santiago de Cali
2020
University of Puerto Rico, Medical Sciences Campus
1982-2019
We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog urban microbial ecosystem. This provides an annotated, geospatial profile strains, functional characteristics, antimicrobial resistance (AMR) markers, and genetic elements, including 10,928 viruses, 1,302 bacteria, 2 archaea, 838,532 CRISPR arrays not found reference databases. identified 4,246 known species microorganisms consistent...
Although disinfection is key to infection control, the colonization patterns and resistomes of hospital-environment microbes remain underexplored. We report first extensive genomic characterization microbiomes, pathogens antibiotic resistance cassettes in a tertiary-care hospital, from repeated sampling (up 1.5 years apart) 179 sites associated with 45 beds. Deep shotgun metagenomics unveiled distinct ecological niches genes characterized by biofilm-forming human-microbiome-influenced...
Herpes simplex virus type 2 (HSV-2) infection is common among human immunodeficiency (HIV)-infected persons, and HSV reactivation increases plasma genital HIV-1 levels. We studied levels during suppression in coinfected persons a placebo-controlled crossover trial.Twenty antiretroviral therapy (ART)-naive HIV-1/HSV-2-seropositive men who have sex with Lima, Peru, CD4 cell counts >200 cells/ microL were randomized to receive either valacyclovir at 500 mg twice daily or placebo for 8 weeks,...
It has long been claimed that a specific histologic diagnosis of mycosis fungoides cannot be made in the “premycotic” or “eczematous” (patch) stage disease. Indeed, features premycotic lesions were constantly said to those “chronic non-specific dermatitis.” We studied 46 biospy specimens patch from patients whom was unequivocally established by clinical events (i.e., concurrence later development typical plaque and/or nodular lesions) and indubitable findings. divided into early nonatrophic...
The association of malignant neoplasms arising contiguous with or adjacent to seborrheic keratoses has been previously documented. In this study a retrospective analysis was performed further characterize these combined neoplasms. A total 54 examples in conjunction were found, which 43 basal cell carcinomas, six Bowen's disease, three keratoacanthomas, and two melanomas. average age the patients over 65 years. Men affected more frequently then women. posterior thorax most common site for...
ABSTRACT: Melasma is characterized by a facial hypermelanosis of light to dark brown color, being more common in women Hispanic origin, this study, 27 men with melasma were evaluated clinically and histologically compare their features those previous studies. Three patterns localization recognized, namely, centrofacial, malar, mandibular. On the basis Wood's examination, an epidermal, dermal, mixed type identified. Epidermal hyperpigmentation only epidermal dermal found histologic analysis...
It has long been claimed that a specific histologic diagnosis of mycosis fungoides cannot be made in the "premycotic" or "eczematous" (patch) stage disease. Indeed, features premycotic lesions were constantly said to those "chronic non-specific dermatitis." We studied 46 biospy specimens patch from patients whom was unequivocally established by clinical events (i.e., concurrence later development typical plaque and/or nodular lesions) and indubitable findings. divided into early nonatrophic...
HIV cross-sectional studies were conducted among high-risk populations in 9 countries of South America. Enzyme-linked immunosorbent assay screening and Western blot confirmatory testing performed, env heteroduplex mobility genotyping DNA sequencing performed on a subset HIV-positive subjects. prevalences highest men who have sex with (MSM; 2.0%-27.8%) found to be associated multiple partners, noninjection drug use (non-IDU), sexually transmitted infections (STIs). By comparison, much lower...
Surveillance for HIV infection among people at increased risk was conducted in five countries South America. Seroprevalence studies were more than 36,000 Ecuador, Peru, Boliva, Uruguay, and Argentina, along with genetic analysis of the HIV-1 strains. In all countries, prevalence men who have sex (MSM) high (3–30%), whereas female commercial workers (FCSMs) low (0.3–6%). By envelope heteroduplex mobility assay, subtype B predominated MSM communities FCSWs Bolivia, Peru. A new screening...
Safety and efficacy of doxycycline in the treatment rosacea Sheila Valentín, Adisbeth Morales, Jorge L Sánchez, Abimael RiveraDepartment Dermatology, University Puerto Rico, School Medicine, San Juan, RicoAbstract: Rosacea is a common, chronic, skin condition characterized by recurrent episodes facial flushing, transient or persistent erythema, papules, pustules, telangiectasias, symmetrical distribution. The etiology remains unknown this represents therapeutic challenge because its chronic...
In most of the few reports about histopathology acrodermatitis enteropathica, changes have been considered to be nonspecific. We undertook a prospective study 12 cases enteropathica in order assess better clinical and histologic features cutancous lesions as thev evolved over time. Early are characterized by loss granular layer, replacement this layer clear cells, focal parakeratosis. As condition progresses, epidermis becomes increasingly psoriasiform, parakeratosis more confluent, pallor...
Tumid lupus erythematosus (TLE) is a subtype of discoid (DLE) whose clinical characteristics rarely have been described in the literature.To describe clinical, histopathologic, and other laboratory findings tumid erythematosus.Clinical were reviewed four patients who had diagnosed with by conventional microscopy. The diagnoses characterized superficial deep perivascular infiltrate lymphocytes deposits mucin foci reticular dermis.All young women. Ages ranged from 16 to 39 years (mean 21...
High levels of human immunodeficiency virus (HIV) in rectal secretions and semen likely increase the risk HIV transmission. HIV-infected men who have sex with made 2-3 study visits, over 4 weeks, to assess rectal, seminal, plasma RNA. Mixed-effects models estimated effect factors on shedding. Twenty-seven (42%) 64 were receiving antiretroviral therapy (ART); regardless ART use, median RNA higher (4.96 log(10) copies/mL) than blood (4.24 or seminal (3.55 copies/mL; P<.05, each comparison)....
Morphea and lichen sclerosus et atrophicus are cutaneous diseases that manifest by an early edematous stage, followed later sclerosis atrophy. They share features with acrodermatitis chronica atrophicans erythema chronicum migrans, have been linked to infection the spirochete Borrelia burgdorferi. A modified silver stain was used identify presence of spirochetes in skin biopsy specimens patients morphea atrophicus. Spirochetal forms were identified lesional 10 25 21 cases These spiral...
Cutaneous pseudolymphoma comprises inflammatory lesions with histologic characteristics that closely resemble malignant lymphoreticular proliferation, but have a benign clinical course. The etiology of this disorder is unknown. We report herein case appearing within resolving herpes zoster in patient chronic lymphocytic leukemia. <h3>Report Case</h3> An 83-year-old man had leukemia diagnosed 1975. He been remission for three years after undergoing oral chemotherapy. In June 1979, he visited...
The antibody responses of human and animal hosts were studied to determine the utility against recombinant tick calreticulin (rTC), a cDNA-derived protein isolated from salivary glands Amblyomma americanum L., as biologic marker exposure. Rabbits fed upon by either A. or Dermacentor variabilis Say developed significant anti-rTC responses, measured both ELISA immunoblot assay. In contrast, gerbils exposed Aedes aegypti did not develop antibodies, assay was next evaluated in humans at high...