A5089443637- Heavy Metal Exposure and Toxicity
- Vector-borne infectious diseases
- Health disparities and outcomes
- Sinusitis and nasal conditions
- Viral Infections and Vectors
- Noise Effects and Management
- Heavy metals in environment
- Trace Elements in Health
- Atmospheric and Environmental Gas Dynamics
- Air Quality and Health Impacts
- Allergic Rhinitis and Sensitization
- Obesity, Physical Activity, Diet
- Climate Change and Health Impacts
- Mercury impact and mitigation studies
- Urban Transport and Accessibility
- Nasal Surgery and Airway Studies
- Mosquito-borne diseases and control
- Carcinogens and Genotoxicity Assessment
- Vector-Borne Animal Diseases
- Folate and B Vitamins Research
- Health, Environment, Cognitive Aging
- Functional Brain Connectivity Studies
- Antimicrobial Resistance in Staphylococcus
- Nutritional Studies and Diet
- Effects and risks of endocrine disrupting chemicals
Geisinger Health System
2016-2025
Johns Hopkins University
2016-2025
University of Michigan
2024
Johns Hopkins Medicine
2014-2023
University of California, San Francisco
2008-2023
Kettering Medical Center
2023
Chinook Regional Hospital
2022
Saint Vincent Hospital
2022
University College London
2022
London Health Sciences Centre
2022
Context.—Tension-type headache is a highly prevalent condition. Because few population-based studies have been performed, little known about its epidemiology.Objectives.—To estimate the 1-year period prevalence of episodic tension-type (ETTH) and chronic (CTTH) in study; to describe differences by sex, age, education, race; attack frequency pain intensity.Design.—Telephone survey conducted 1993 1994.Setting.—Baltimore County, Maryland.Participants.—A total 13345 subjects from community.Main...
The objective of this study was to describe the first US-based use European Position Paper on Rhinosinusitis (EPOS) criteria prevalence chronic rhinosinusitis (CRS) in a general-population sample.A CRS symptom questionnaire mailed 23 700 primary care patients from Geisinger Clinic, health system serving 45 counties Pennsylvania. cases were categorized into four unique subgroups based EPOS symptoms: obstruction and discharge with no smell loss or pain/pressure; without facial pain and/or...
Unconventional natural gas development has expanded rapidly. In Pennsylvania, the number of producing wells increased from 0 in 2005 to 3,689 2013. Few publications have focused on unconventional and birth outcomes. We performed a retrospective cohort study using electronic health record data 9,384 mothers linked 10,946 neonates Geisinger Health System January 2009 estimated cumulative exposure activity with an inverse-distance squared model that incorporated distance mother's home; dates...
Procedural success and clinical outcomes after transcatheter aortic valve replacement (TAVR) have improved, but residual regurgitation (AR) new permanent pacemaker implantation (PPI) rates remain variable because of a lack uniform periprocedural management implantation.The Optimize PRO study evaluates performance procedural using an "optimized" TAVR care pathway the cusp overlap technique (COT) in patients receiving Evolut PRO/PRO+ (Medtronic) self-expanding valves.Optimize PRO,...
Journal Article Ethnic differences in the prevalence of homozygous deleted genotype glutathione S-transferase theta Get access Heather H. Nelson, Nelson 1Department Cancer Biology. Harvard School Public Health665 Huntington Avenue, Boston, MA 02115 Search for other works by this author on: Oxford Academic PubMed Google Scholar John K. Wiencke, Wiencke 2Laboratory Molecular Epidemiology. Department Epidemiology and Biostatistics, Medicine, University California-San FranciscoSan Francisco, CA...
A geographic information system was used to identify and locate residential environmental risk factors for Lyme disease.Data were obtained 53 variables at the residences of disease case patients in Baltimore County from 1989 through 1990 compared with data randomly selected addresses. model generated combining logistic regression analysis. The validated by comparing distribution cases 1991 another group addresses.In crude analyses, 11 associated disease. In adjusted residence forested areas...
<h3>Context</h3> The stress responses of the hypothalamic-pituitary-adrenal axis can produce adverse effects on brain. Previous studies have concluded that an elevated level cortisol is a risk factor for cognitive dysfunction and decline in aging but been limited by sex exclusion, restricted batteries, small sample sizes. <h3>Objective</h3> To examine associations among salivary metrics domain scores urban adult population. <h3>Design, Setting, Participants</h3> A cross-sectional analysis...
Little is known about the impact of different types headache on lost work time and effectiveness in United States. Estimation distribution magnitude workplace necessary before interventions can be developed. During 1993 1994 Baltimore County, Maryland, study subjects were contacted by random-digit dialing interviewed telephone their headaches. Headache diagnoses assigned using International Society criteria for migraine episodic tension-type headache. Measures derived based self-reports...
<b><i>Objective:</i></b> To determine whether adults with past exposure to neurotoxicants have progressive declines in cognitive function years after has ceased, and tibia lead is a predictor of the magnitude change. <b><i>Methods:</i></b> A total 535 former organolead manufacturing workers mean age 55.6 years, duration 16 since last occupational exposure, low blood levels at first study visit 118 controls were evaluated neurobehavioral tests two four times over 4 years. “Peak” levels,...
Methicillin-resistant Staphylococcus aureus (MRSA) infections have become a major public health problem in both the community and hospitals. Few studies characterized incidence clonal composition of disease-causing strains an entire population. Our objective was to perform population-based survey clinical molecular epidemiology MRSA disease San Francisco, California.We prospectively collected 3985 isolates associated demographic information over 12-month period (2004-2005) at 9...
ObjectivesDrawing from collective efficacy and social disorganization theories, we developed validated measures of neighborhood-level processes.
Contaminated pharmaceutical products can result in substantial morbidity and mortality should be included the differential diagnosis of deaths unknown origin.To investigate an outbreak among children from acute renal failure Haiti to determine etiology institute control measures.Case-control study, cohort laboratory toxicologic evaluation.Pediatric population Haiti.Cases were defined as Haitian residents younger than 18 years with idiopathic anuria or severe oliguria for 24 hours longer....
<b>Objective: </b> To determine whether cumulative lead dose in former organolead workers was associated with MRI measures of white matter lesions (WML) and global structure-specific brain volumes. <b>Methods: MRIs, tibia lead, other were obtained from 532 a mean age 56 years 18 since last occupational exposure to lead. Cumulative measured by X-ray fluorescence, expressed as μg per gram bone mineral (μg Pb/g). WML evaluated using the Cardiovascular Health Study grading scale. A total 21...
Nearly 80% of antibiotics in the United States are sold for use livestock feeds. The manure produced by these animals contains antibiotic-resistant bacteria, resistance genes, and is subsequently applied to crop fields, where it may put community members at risk infections.To assess association between individual exposure swine dairy/veal industrial agriculture methicillin-resistant Staphylococcus aureus (MRSA) infection.A population-based, nested case-control study primary care patients...
<h3>Importance</h3> Asthma is common and can be exacerbated by air pollution stress. Unconventional natural gas development (UNGD) has community environmental impacts. In Pennsylvania, UNGD began in 2005, 2012, 6253 wells had been drilled. There are no prior studies of objective respiratory outcomes. <h3>Objective</h3> To evaluate associations between asthma exacerbations. <h3>Design</h3> A nested case-control study comparing patients with without exacerbations from 2005 through 2012 treated...
Although a link between body mass index (BMI) and brain volume has been established in several cross-sectional studies, evidence of the association change BMI over time changes structure is limited. Using data from cohort 347 former lead workers community controls with two magnetic resonance imaging scans period ~5 years, we estimated longitudinal associations using both region interest (ROI) voxel-based morphometric (VBM) methods. We found that were not significantly different when compared...