A5047671590- Sinusitis and nasal conditions
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Nasal Surgery and Airway Studies
- Respiratory and Cough-Related Research
- Drug-Induced Adverse Reactions
- Head and Neck Surgical Oncology
- IL-33, ST2, and ILC Pathways
- Otitis Media and Relapsing Polychondritis
- Eosinophilic Esophagitis
- Pediatric health and respiratory diseases
- Cystic Fibrosis Research Advances
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Dermatology and Skin Diseases
- Immunodeficiency and Autoimmune Disorders
- Infectious Diseases and Mycology
- Mycobacterium research and diagnosis
- Olfactory and Sensory Function Studies
- Urticaria and Related Conditions
- Voice and Speech Disorders
- Inhalation and Respiratory Drug Delivery
- Inflammatory mediators and NSAID effects
- Food Allergy and Anaphylaxis Research
- S100 Proteins and Annexins
- Congenital Ear and Nasal Anomalies
Northwestern University
2016-2025
University of Pittsburgh
2024-2025
University of Chicago
2025
Washington University in St. Louis
2024-2025
Rush University Medical Center
2016-2021
University of California, San Francisco
2021
ENT and Allergy
2011-2020
Northwestern Medicine
2020
Stanford Medicine
2020
University of Mississippi Medical Center
2020
Objective This update of a 2007 guideline from the American Academy Otolaryngology—Head and Neck Surgery Foundation provides evidence‐based recommendations to manage adult rhinosinusitis, defined as symptomatic inflammation paranasal sinuses nasal cavity. Changes prior include consumer added group, evidence 42 new systematic reviews, enhanced information on patient education counseling, algorithm clarify action statement relationships, expanded opportunities for watchful waiting (without...
The mechanisms that underlie the pathogenesis of chronic rhinosinusitis without nasal polyps (CRSsNP), with (CRSwNP), and aspirin-exacerbated respiratory disease (AERD) are not clear.To first evaluate inflammatory profiles CRSsNP CRSwNP tissues then to investigate whether clinical differences observed between AERD in part secondary mediator expression within polyp (NP) tissues.Expression levels numerous mediators were determined by quantitative real-time polymerase chain reaction, ELISA,...
The American Academy of Otolaryngology—Head and Neck Surgery Foundation has published a supplement to this issue featuring the updated “Clinical Practice Guideline: Adult Sinusitis” as Otolaryngology–Head . To assist in implementing guideline recommendations, article summarizes rationale, purpose, key action statements. 14 developed recommendations address diagnostic accuracy for adult rhinosinusitis, appropriate use ancillary tests confirm diagnosis guide management (including radiography,...
Severe chronic rhinosinusitis with nasal polyps (CRSwNP), a form of diffuse bilateral (usually type 2) CRS, is debilitating disease significant impact on quality life (QoL). With novel knowledge and treatment options becoming available, there growing need to update or revise key definitions enable communication across different specialties dealing agree goals care in CRSwNP. The European Forum for Research Education Allergy Airway diseases (EUFOREA) EPOS expert members discussed how measure...
Background There is a clinical association between asthma and chronic rhinosinusitis (CRS). This study was designed to determine whether severity of coexistent affects the presentation CRS. Methods Cross-sectional analysis performed prospectively collected data in 187 patients with CRS who were evaluated large, tertiary academic nasal sinus center. Patients stratified into three groups based on status using National Institutes Health criteria: (1) nonasthmatic, (2) intermittent/mild asthma,...
Rhinitis is an umbrella term that encompasses many different subtypes, several of which still elude complete characterization. The concept phenotyping, being the definition disease subtypes on basis clinical presentation, has been well established in last decade. Classification rhinitis entities phenotypes facilitated their characterization and helped practicing clinicians to efficiently approach patients. Recently, endotypes, is, underlying pathophysiology, emerged. Phenotypes/endotypes are...
Nasal polyps (NPs) are characterized by intense edema or formation of pseudocysts filled with plasma proteins, mainly albumin. However, the mechanisms underlying NP retention proteins in their submucosa remain unclear.We hypothesized that a fibrin mesh retains NPs. We assessed deposition and expression components fibrinolytic system patients chronic rhinosinusitis (CRS).We nasal tissue from CRS control subjects means immunofluorescence. Fibrinolytic components, d-dimer, plasminogen...