- Asthma and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- HIV/AIDS Research and Interventions
- Sex work and related issues
- HIV, Drug Use, Sexual Risk
- Respiratory and Cough-Related Research
- Pediatric health and respiratory diseases
- Air Quality and Health Impacts
- Health and Lifestyle Studies
- Adolescent Sexual and Reproductive Health
- Allergic Rhinitis and Sensitization
- Menstrual Health and Disorders
- Lipoproteins and Cardiovascular Health
- Obesity, Physical Activity, Diet
- Travel-related health issues
- Metabolomics and Mass Spectrometry Studies
- Occupational exposure and asthma
- Inhalation and Respiratory Drug Delivery
- Noise Effects and Management
- Palliative Care and End-of-Life Issues
- Respiratory Support and Mechanisms
- School Health and Nursing Education
- Grief, Bereavement, and Mental Health
- HIV Research and Treatment
- Syphilis Diagnosis and Treatment
Universidad de Huelva
2015-2024
Agenzia Regionale Prevenzione e Ambiente della Regione Emilia-Romagna
2023
Hospital Juan Ramón Jiménez
1995-2020
Walter Reed Army Institute of Research
1990-2020
Armed Forces Health Surveillance Center
2008-2020
Hospital Clínico Universitario Lozano Blesa
2018
Universidad Nacional de Colombia
2018
University of Bergen
2017
Henry M. Jackson Foundation
2005-2016
Hospital General Universitario De Valencia
2009
Abstract Interannual climate variability patterns associated with the El Niño-Southern Oscillation phenomenon result in and environmental anomaly conditions specific regions worldwide that directly favor outbreaks and/or amplification of variety diseases public health concern including chikungunya, hantavirus, Rift Valley fever, cholera, plague, Zika. We analyzed some disease during strong 2015–2016 Niño event relation to anomalies derived from satellite measurements. Disease multiple...
Rationale: Menopause is associated with changes in sex hormones, which affect immunity, inflammation, and osteoporosis may impair lung function. Lung function decline has not previously been investigated relation to menopause.Objectives: To study whether decline, assessed by FVC FEV1, accelerated women who undergo menopause.Methods: The population-based longitudinal European Community Respiratory Health Survey provided serum samples, spirometry, questionnaire data about respiratory...
Mothers' smoking during pregnancy increases asthma risk in their offspring. There is some evidence that grandmothers' may have a similar effect, and biological plausibility fathers' adolescence influence offspring's health through transmittable epigenetic changes sperm precursor cells. We evaluated the three-generation associations of tobacco with asthma. Between 2010 2013, at European Community Respiratory Health Survey III clinical interview, 2233 mothers 1964 fathers from 26 centres...
To determine the efficacy of loperamide given with long- and short-course quinolone therapy for treating traveler's diarrhea, 142 US military personnel were randomized to receive a single 750-mg dose ciprofloxacin placebo, 750 mg ciproftoxacin loperamide, or 3-day course 500 twice daily loperamide. Culture pretreatment stool specimens revealed campylobacters (41%), salmonellae (18%), enterotoxigenic Escherichia coli (ETEC, 6%), shigellae (4%). Of participants, 87% completely recovered within...
To compare the safety and efficacy of loperamide used in combination with ciprofloxacin or alone for treatment travelers' diarrhea.Double-blind, placebo-controlled, randomized clinical trial.United States Army hospital Egypt.United military personnel diarrhea (n = 104) during a exercise November 1989. Persons who were noncompliant, had bloody diarrhea, received antidiarrheal medications before entry into study excluded.All participants treated ciprofloxacin, 500 mg twice daily 3 days. Fifty...
Objective: To assess and estimate trends in HIV, sexually transmitted infections (STIs), sexual behavior among men who have sex with (MSM) Lima, Peru. Design: Second-generation HIV sentinel surveillance surveys conducted 1996, 1998, 2000, 2002. Methods: Adult reporting at least 1 man during the previous year were eligible to participate. Sexual serum HIV-1 syphilis antibodies assessed. seroincidence was estimated by a sensitive/less-sensitive enzyme immunoassay strategy. Rectal pharyngeal...
We assessed associations between physical activity and lung function, its decline, in the prospective population-based European Community Respiratory Health Survey cohort.FEV1 FVC were measured 3912 participants at 27-57 years 39-67 (mean time examinations=11.1 years). Physical frequency duration using questionnaires used to identify active individuals (physical ≥2 times ≥1 hour per week) each examination. Adjusted mixed linear regression models of regular with FEV1 FVC.Physical increased...
Previous studies have reported an association between weight increase and excess lung function decline in young adults followed for short periods. We aimed to estimate trajectories during adulthood from 20-year change profiles using data the population-based European Community Respiratory Health Survey (ECRHS).
Objectives Recent studies have shown an excess risk of asthma for cleaners, but it is not clear which cleaning-related exposures induce or aggravate asthma. Methods Risk factors were studied among indoor cleaners participating in the Spanish part European Community Respiratory Health Survey 1992. In 1998, 78 91 subjects reporting jobs 1992 identified. Of these, 67 interviewed by telephone about their cleaning activities and use products These data related to prevalence 1992, compared with a...
A vancomycin population pharmacokinetic prediction model for adult and elderly patients was developed using NONMEM. The predictability of the studied compared with ten other models.Data were collected from routine care 141 subjects. NONMEM used to derive a model. After internal evaluation bootstrap technique, external validation an independent dataset that consisted 95 subjects; statistical comparison precision bias conducted.A two-compartment open derived body weight, age, CLcr as...
Life course data on obesity may enrich the quality of epidemiologic studies analysing health consequences obesity. However, achieving such require substantial resources. We investigated use body silhouettes in adults as a tool to reflect past. used large population-based samples analyse what extent self-reported correlated with previously measured (9–23 years) mass index (BMI) from both (European Community Respiratory Health Survey, N = 3 041) and (Respiratory In Northern Europe study, 410)...
Activity-related breathlessness is twice as common among females males in the general population and associated with adverse health outcomes. We tested whether this sex difference explained by lower absolute forced expiratory volume 1 s (FEV ) or vital capacity (FVC) females. This was a cross-sectional analysis of 3250 subjects (51% female) aged 38−67 years across 13 countries population-based third European Community Respiratory Health Survey. measured using modified Medical Research...
Obesity is a known risk factor for asthma. Although some evidence showed asthma causing obesity in children, the link between and has not been investigated adults.We used data from European Community Respiratory Health Survey (ECRHS), cohort study 11 countries Australia 3 waves 1990 2014, at intervals of approximately 10 years. We considered two periods: ECRHS I (t) to II (t+1), III (t+1). excluded obese (body mass index≥30 kg/m2) individuals visit t. The relative (RR) t+1 associated with t...
Surveillance for HIV infection among people at increased risk was conducted in five countries South America. Seroprevalence studies were more than 36,000 Ecuador, Peru, Boliva, Uruguay, and Argentina, along with genetic analysis of the HIV-1 strains. In all countries, prevalence men who have sex (MSM) high (3–30%), whereas female commercial workers (FCSMs) low (0.3–6%). By envelope heteroduplex mobility assay, subtype B predominated MSM communities FCSWs Bolivia, Peru. A new screening...
Menopause is associated with a number of adverse health effects and its timing has been reported to be influenced by several lifestyle factors. Whether greenspace exposure age at menopause not yet investigated. To investigate whether residential surrounding thus reproductive aging. This longitudinal study was based on the 20-year follow-up 1955 aging women from large, population-based European cohort (ECRHS). Residential abstracted as average satellite-based Normalized Difference Vegetation...
Concerns exist that the positive association of physical activity with better lung function, which has been suggested in previous longitudinal studies smokers, is due to reverse causation. To investigate this, we applied structural equation modeling (SEM), an exploratory approach, and marginal (MSM), approach from causal inference framework corrects for causation time-dependent confounding estimates effects, on data participants European Community Respiratory Health Survey (ECRHS, a...
Mechanistic research suggests that lifestyle and environmental factors impact respiratory health across generations by epigenetic changes transmitted through male germ cells. Evidence from studies on humans is very limited. We investigated multigeneration causal associations to estimate the effects of tobacco smoking lung function within paternal line. analysed data 383 adult offspring (age 18–47 years; 52.0% female) their 274 fathers, who had participated in European Community Respiratory...
Background and Objectives: Dementia grief in family caregivers of people with dementia refers to grieving prior the death care recipient. It is related psychosocial risk factors that may have a negative impact on health these caregivers. This study aimed describe relationship between depressive symptoms, caregiver strain, social support dementia. Materials Methods: A descriptive correlational cross-sectional was conducted. total 250 participated. main variable, were assessed. Additionally,...
Self-report questionnaires are commonly used in epidemiology, but may be susceptible to misclassification, especially if answers given on behalf of others, e.g. children or parents. The aim was determine agreement and analyse predictors disagreement parents' reports offspring asthma, asthma. In the Respiratory Health Northern Europe, Spain Australia (RHINESSA) generation study, 6752 (age range 18–51 years) their parents 39–66 reported own each other's asthma status. Agreement between from...
The few studies that have examined associations between greenspace and lung function in adulthood yielded conflicting results none whether the rate of decline is affected.We explored association residential change over 20 years 5559 adults from 22 centers 11 countries participating population-based, international European Community Respiratory Health Survey.Forced expiratory volume 1 s (FEV1) forced vital capacity (FVC) were measured by spirometry when participants approximately 35...