A5084852976- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- COVID-19 Clinical Research Studies
- Biosensors and Analytical Detection
- Bacterial Identification and Susceptibility Testing
- Long-Term Effects of COVID-19
- Antibiotic Resistance in Bacteria
- Respiratory viral infections research
- Cytomegalovirus and herpesvirus research
- Herpesvirus Infections and Treatments
- Advanced biosensing and bioanalysis techniques
- COVID-19 epidemiological studies
- Nosocomial Infections in ICU
- Antibiotic Use and Resistance
- Immune Cell Function and Interaction
- Antibiotics Pharmacokinetics and Efficacy
- Infective Endocarditis Diagnosis and Management
- Hematopoietic Stem Cell Transplantation
- Pneumonia and Respiratory Infections
- Retinal and Optic Conditions
- Mycobacterium research and diagnosis
- Retinal Diseases and Treatments
- COVID-19 diagnosis using AI
- Streptococcal Infections and Treatments
- Animal Virus Infections Studies
INCLIVA Health Research Institute
2017-2024
Hospital Clínico Universitario de Valencia
2022-2024
University of Concepción
2023
Loyola University Medical Center
2019
Polytechnic University of Queretaro
2012
National Institute of Quality
2009
Universidad de Antioquia
2005
The 2023 monkeypox (mpox) epidemic was caused by a subclade IIb descendant of virus (MPXV) lineage traced back to Nigeria in 1971. Person-to-person transmission appears higher than for clade I or IIa MPXV, possibly genomic changes MPXV. Key could occur the genome's low-complexity regions (LCRs), which are challenging sequence and often dismissed as uninformative. Here, using combination highly sensitive techniques, we determine high-quality MPXV genome representative current with LCRs...
We present a preliminary analysis of 1,771 confirmed cases influenza A(H1N1)v reported in Peru by 17 July including the frequency clinical characteristics, spatial and age distribution estimate transmission potential. Age-specific was highest among school children young adults, with lowest seniors, pattern that is consistent reports from other countries. Estimates reproduction number lie range 1.2 to 1.7, which broadly previous estimates for this pandemic regions. Validation these will be...
There is limited information on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) T-cell immune responses in patients with disease 2019 (COVID-19). Both CD4+ and CD8+ T cells may be instrumental resolution of protection from SARS-CoV-2 infection. Here, we tested 25 hospitalized either microbiologically documented COVID-19 (n = 19) or highly suspected having the 6) for presence SARS-CoV-2-reactive CD69+ expressing interferon-γ (IFN-γ) producing using flow-cytometry intracellular...
Whether antibody levels measured by commercially available enzyme or chemiluminescent immunoassays targeting the SARS-CoV-2 spike (S) protein can act as a proxy for serum neutralizing activity remains to be established many of these assays. We evaluated degree correlation between antibodies (NtAb) binding and SARS-CoV-2-S-IgG four commercial in sera drawn from hospitalized COVID-19 patients. Ninety 51 patients were tested pseudotyped virus neutralization assay, LIAISON S1/S2 IgG, Euroimmun...
Abstract Immunosenescence may impact the functionality and breadth of vaccine-elicited humoral immune responses. The ability sera to neutralize SARS-CoV-2 spike protein (S) from Beta, Gamma, Delta, Epsilon variants concern (VOCs) relative ancestral Wuhan-Hu-1 strain was compared in Comirnaty COVID-19-vaccinated elderly nursing home residents, either naïve (n = 22) or experienced 8), younger individuals 18) non-vaccinated who recovered severe COVID-19 19). In all groups, except that including...
Abstract We evaluated the Panbio™ COVID-19 AG Rapid Test Device (RAD) for diagnosis of in symptomatic patients attended primary healthcare centers (n=412). Overall specificity and sensitivity RAD was 100% 79.6%, respectively, taking RT-PCR as reference. SARS-CoV-2 could not be cultured from specimens yielding RT-PCR+/RAD- results.
Several studies evaluating the performance of Rapid antigen assays (RAD) for diagnosis SARS-VCoV-2 infection have been recently published in this Journal.1Azzi L. Baj A. Alberio T. Lualdi M. Veronesi G. Carcano et al.Rapid salivary test suitable a mass screening program to detect SARS-CoV-2: diagnostic accuracy study. rapid nurse staff research group,.J Infect. 2020; 81 (Grossi PA, Tagliabue A, Fasano M): e75-e78Abstract Full Text PDF PubMed Scopus (53) Google Scholar, 2Agulló V....
Abstract A third Comirnaty vaccine dose increased severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain antibody levels (median, 93-fold) and neutralizing titers against Wuhan-Hu-1 57-fold), Beta (me 22-fold), Delta, 43-fold), Omicron 8-fold) variants, but had less impact on S-reactive T-cell immunity in nursing home residents.
Klebsiella pneumoniae is a resistant pathogen involved primarily in hospital-acquired infections. This characterized by its notorious resistance to last-line antibiotics, such as carbapenems.
The Platelia Aspergillus Antigen immunoassay is the "gold standard" for galactomannan (GLM) measurement in sera and bronchoalveolar lavage (BAL) diagnosis of invasive pulmonary aspergillosis (IPA). We evaluated performance GLM antigen Virclia Monotest compared to assay. A total 535 specimens [320 sera, 86 bronchial aspirates (BAs), 70 BAL, 59 tracheal (TAs)] from 177 adult patients (72 hematological, 32 Intensive Care Unit, 73 hospitalized other wards) were processed testing upon clinical...
We evaluated the Panbio™ COVID-19 Ag Rapid Test Device as a point-of-care diagnostic tool for in 357 patients at pediatric emergency department. Thirty-four tested positive by reverse transcription polymerase chain reaction, of which 24 were antigen assay. The sensitivity and specificity assay 70.5% 100%, respectively.