- Mosquito-borne diseases and control
- Lung Cancer Treatments and Mutations
- Viral Infections and Vectors
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Diagnosis and Treatment
- BRCA gene mutations in cancer
- Breast Cancer Treatment Studies
- Malaria Research and Control
- Global Cancer Incidence and Screening
- Women's cancer prevention and management
- Anesthesia and Pain Management
- Dermatological and Skeletal Disorders
- Cancer Diagnosis and Treatment
- Advanced Causal Inference Techniques
- COVID-19 epidemiological studies
- Cancer survivorship and care
- Bone Metabolism and Diseases
- Vector-Borne Animal Diseases
- Economic and Financial Impacts of Cancer
- Global Maternal and Child Health
- Gastric Cancer Management and Outcomes
- Tracheal and airway disorders
- COVID-19 and healthcare impacts
- Ovarian cancer diagnosis and treatment
- Nerve Injury and Rehabilitation
Sociedade Brasileira de Oncologia Clínica
2020-2023
University of Magdalena
2020-2021
Institute of Agrifood Research and Technology
2021
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria
2021
University of Cartagena
2021
United States Naval Medical Research Unit SOUTH
2021
Universidad de Antioquia
2012-2020
Instituto de Cancerología Las Américas
2018
Corporación Universitaria Remington
2014
Fundación Universitaria Internacional del Tropico Américano
2014
Dengue is an important public health problem worldwide. A vaccine has recently been licensed in some countries of Latin America and Asia. Recommendations for dengue introduction include endemicity a high serological prevalence the territories considering its introduction.
We describe an Oropouche orthobunyavirus infection in a women 28 years of age Colombia. confirmed the diagnosis by viral isolation, quantitative reverse transcription PCR, and phylogenetic analysis small, medium, large genomic segments. The virus is related to strain isolated Ecuador 2016.
Dengue fever is a major public health problem in Colombia. A surveillance study was conducted for evaluation of the clinical, epidemiological, and molecular patterns dengue, prior to Chikungunya Zika epidemics. In November 2011–February 2014, passive facility-based implemented Santa Cruz Hospital, Medellin, enrolled eligible febrile patients between 1 65 years-of-age. Acute convalescent blood samples were collected 10–21 days apart tested dengue using IgM/IgG ELISA. RNA extracted serotyping...
PURPOSE Locally advanced cervical cancer may present with uncontrollable vaginal bleeding in up to 70% of cases. Pelvic vessel embolization has been used as an urgent maneuver for achieving fast hemostatic control. This report describes outcomes selective pelvic patients severe due a locally cancer. METHODS In this retrospective study, technical aspects, clinical variables, and bleeding-related morbidity were described. The frequency recurrent disease the vital status at 1 year follow-up...
Resumen: El objetivo fue estimar el efecto del aseguramiento en salud sobre la supervivencia global y libre de enfermedad pacientes con cáncer mama. La muestra se compuso mujeres operadas Instituto Cancerología, Medellín, Colombia, datos registro institucional. Las variables compararon entre régimen subsidiado contributivo com chi cuadrado test (χ2) o t Student, método Kaplan-Meier prueba rangos logarítmicos (log-rank test). variable interés ajustó una regresión Cox. Se incluyeron 2.732...
Purpose: This is the first report of an institutional-based cancer registry in Clínica de Oncología Astorga, Medellín, Colombia. It was created to produce local information on socio-demographic and clinical characteristics, therapies, survival outcomes patients with most frequent tumors institution. Methods: All consecutive cancers breast (BC), prostate (PC), lung (LC), colorectal (CRC), ovarian, stomach, pancreas, cervical, melanoma, diagnosed after January 1/2019, treated at institution...
INTRODUCCIÓNEn la investigación clínica puede buscarse de dos maneras asociación entre fenómenos o factores biológicos: por medio estudios experimentales no experimentales.En los experimentales, conocidos en literatura como observacionales (casos y controles, cohortes transversales), el investigador aprovecha oportunidad abordar fenómeno tal se presenta, sin poder controlar las variables que lo modifican, atenúan acentúan, sean estas conocidas desconocidas.En específicamente ensayo clínico...
Los insectos relacionados con la transmisión de los patógenos causantes las leishmaniasis han sido poco estudiados en Sierra Nevada Santa Marta, Colombia, incluido el departamento Magdalena, donde a fecha están registradas trece especies del género Lutzomyia.En presente nota se informa hallazgo tres y un subgénero adicionales región.Se recolectaron 885 flebotomíneos Seywiaka veredas Las Tinajas Calabazo, estribaciones Marta (117-130 m s.n.m.).El 84 % ejemplares obtuvieron trampa CDC, 11...
Nivolumab is a human programmed death receptor-1 blocking antibody, used as treatment option in patients with advanced non-small-cell lung cancer (NSCLC). We assessed the nivolumab efficacy terms of survival and response to second-line (2L) or third-line (3L) therapy NSCLC. This multicentric observational study. Data NSCLC who received 2L 3L were analyzed retrospectively. Information regarding patient demographics clinical backgrounds, patterns from diagnosis post-nivolumab treatment,...
Abstract Cleidocranial dysplasia is a rare disease with an autosomal‐dominant inheritance that mainly affects the bones of axial skeleton. In this report, we discuss clinical and radiological signs case series comprising three sisters son one sisters, all suspected bone dysplasia.
Context: Several investigations have shown that people in an adoption situation a higher frequency of mental problems or disorders than the general population. However, no known meta-analysis consolidates information about association between and suicide attempt. Objectives: We aimed to systematically evaluate primary observational studies quantified being adopted Methods: A systematic review was designed used logical strategy based on specific descriptors Spanish, English, Portuguese,...
Bajo las nuevas condiciones generadas por la pandemia de COVID-19, los tratamientos para el cáncer mama requieren algunas reorientaciones y cuidados que se exponen en este artículo. Se consideran aquí tres fases gravedad respectivos demandan función lineamientos dictados Ministerio Salud Protección Social Colombia. trata un conjunto referencias orientar terapias tratamientos, inspiradas políticas salud regionales, nacionales e institucionales.
e12521 Background: The genomic-based 21-gene recurrence-score assay (Oncotype DX, Genomic Health)(ODx) is used to decide on the use of adjuvant chemotherapy (ACT) in luminal-type Early-Breast Cancer (LT-EBC). Patients with low RS can safely avoid ACT. Other predictive models based standard clinical and histopathological (C&H) variables also have been developed. These include, Magee equations (ME), Predict model (PM), Tennessee nomogram score (TNS). This study aims establish concordance...
The STOP-Bang has been promoted as a valuable tool for identifying obstructive sleep apnea-hypopnea syndrome (OSAHS) in medical and surgical patients. However, its performance Colombian samples is unknown. objective of this study was to determine the clinimetric index versus polysomnography patients from Santa Marta, Colombia. An accuracy diagnostic tests with test-based approach designed. Seven hundred sixty-two adults referred evaluate OSAHS were included research. They aged between 18 94...
Objetivos: el nivolumab es un anticuerpo monoclonal contra PD-L1 (programmed death receptor-1) usado como opción terapéutica en pacientes con cáncer de pulmón células no pequeñas (CPCNP) avanzado. Este estudio tuvo objetivo evaluar la experiencia segunda (2L) y tercera línea (3L) tratamiento CPCNP avanzado, diferentes centros oncológicos Colombia.
Introducción: el conocimiento demográfico y de supervivencia del cáncer en Colombia es limitado, sin embargo, intento mejorar este registro está aumento. La Clínica Oncología Astorga un centro tercer nivel que brinda atención especializada Medellín, Colombia. En año 2019 se creó institucional para describir las características sociodemográficas, clínicas, terapéuticas los resultados diez tipos tumores sólidos más frecuentes la institución.
Objetivo: La prueba genómica de recurrencia 21 genes (Oncotype DX, Genomic Health) (ODx®) permite determinar la utilidad quimioterapia adyuvante en pacientes con cáncer mama temprano tipo luminal. De forma segura se puede omitir un puntaje riesgo bajo (RB). También han desarrollado otros modelos predictivos basados variables clínicas e histopatológicas estándar. Estos incluyen las ecuaciones Magee (EM), el modelo Predict (MP) y puntuación del nomograma Tennessee (NT). El objetivo este...
Introduction: survival outcomes of Non-Small Cell Lung Cancer (NSCLC) reported in the literature may not apply to patients a real-life scenario Colombia. This study aims describe these cohort with NSCLC treated at Clínica de Oncología Astorga, Medellín, Methods: this is an observational analysis. Patients advanced established from January 1/2019 Institution were included. Medical records analyzed retrospectively. Kaplan Meier method was used estimate progression-free (PFS) and overall (OS)....
Background: Dengue infection is a major public health problem in Colombia where the largest epidemic with almost 157,000 DF cases and 217 deaths were reported 2010. However, comprehensive data are scarce, yet essential for decision-making dengue vaccines introduction. Methods: We conducting study composed of passive facility-based surveillance; sero-survey; healthcare utilization survey; cost-of-illness (COI) willingness-to-pay (WTP) survey to determine true burden Santa Cruz comuna...
Abstract Background: Mastectomy is associated with acute and chronic postoperative pain. This study investigated the efficacy of thoracic paravertebral block (TPB) compared to local anesthetic surgical wound (LASW) in breast cancer patients undergoing mastectomy. Methods: phase 3, randomized controlled, single blind, parallel arms superiority clinical trial aimed evaluate TPB LASW on pain at rest motion 24 hours post-mastectomy, measured by a visual analog scale (VAS). The size 60 determined...
Objetivo: Describir los aspectos clínicos, la supervivencia libre de progresión (SLP) y global (SG) en una cohorte pacientes con cáncer ovario avanzado establecer las diferencias entre tratadas quimioterapia o sin bevacizumab Clínica Oncología Astorga, Medellín.
 Materiales métodos: Estudio observacional retrospectiva que recibieron tratamiento 2012 2018, análisis supervivencia. Se realizó estadística descriptiva Kaplan-Meier para general por grupo, se estimó el cociente riesgo...
e21094 Background: Nivolumab is a human programmed death receptor-1 (PD-1) blocking antibody, used as treatment option in patients with advanced non-small cell lung cancer (NSCLC). We assessed the nivolumab efficacy terms of survival and response to second- or third-line therapy NSCLC. Methods: This multicentric observational study. Data NSCLC who received second (2L) (3L) were analyzed retrospectively. Information regarding patient demographics clinical backgrounds, patterns from diagnosis...