Yue Hu

ORCID: 0000-0003-4423-5744
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About
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Research Areas
  • Inflammasome and immune disorders
  • IL-33, ST2, and ILC Pathways
  • Tryptophan and brain disorders
  • Asthma and respiratory diseases
  • Advanced biosensing and bioanalysis techniques
  • Luminescence and Fluorescent Materials
  • Plant Pathogens and Fungal Diseases
  • Advanced Nanomaterials in Catalysis
  • Immune Response and Inflammation
  • thermodynamics and calorimetric analyses
  • Biochemical Analysis and Sensing Techniques
  • Wnt/β-catenin signaling in development and cancer
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Cancer-related gene regulation
  • Toxin Mechanisms and Immunotoxins
  • Extracellular vesicles in disease
  • Advancements in Transdermal Drug Delivery
  • Nanocluster Synthesis and Applications
  • 14-3-3 protein interactions
  • Bacterial biofilms and quorum sensing
  • Heat shock proteins research
  • Antibiotic Resistance in Bacteria
  • Biosensors and Analytical Detection
  • Parasites and Host Interactions
  • Helminth infection and control

Liaoning University of Traditional Chinese Medicine
2024

Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
2024

Yantai University
2024

Ruijin Hospital
2024

Shanghai Jiao Tong University
2024

Nanjing University of Chinese Medicine
2017-2023

Lanzhou Institute of Chemical Physics
2023

Chinese Academy of Sciences
2023

Hebei Medical University
2022

Shanghai Institute of Landscape Gardening
2022

Activation of Wnt/β-catenin signaling plays a central role in the development and progression colorectal cancer. The Wnt-transcription factor, TCF7L2, is overexpressed primary rectal cancers that are resistant to chemoradiotherapy TCF7L2 mediates resistance chemoradiotherapy. However, it unclear whether mediated by inherent mechanism or general. Here, inhibition β-catenin siRNAs small-molecule inhibitor (XAV-939) resulted sensitization cancer cells To investigate potential controlling...

10.1158/1541-7786.mcr-17-0205 article EN Molecular Cancer Research 2017-08-16

Background: Pilose antler peptide (PAP), prepared from the pilose of Cervus nippon Temminck, is widely used in traditional Chinese medicine (TCM) against various inflammatory disorders. TCM prescriptions containing are often prescribed clinically to treat depression. However, pharmacological mechanisms how PAP, inflammation, prevents and treats depression remain poorly understood. Methods: PAP was identified by de novo sequencing database searching. Then, behavioral tests were conducted...

10.3389/fphar.2022.815413 article EN cc-by Frontiers in Pharmacology 2022-03-23

Pseudomonas aeruginosa continues to be a predominant cause of infections with high intrinsic resistance antibiotics, resulting in treatment failure. P. is the leading respiratory among cystic fibrosis (CF) patients. Resistance carbapenem antibiotics has been reported. Thus, this study was undertaken characterize metallo‑β‑lactamase (MBL) production by phenotypic and genotypic methods. A total 572 sputum samples were collected from patients along patient demographic details questionnaire. In...

10.3892/mmr.2014.2685 article EN Molecular Medicine Reports 2014-10-16

Abstract Asthma, a pervasive pulmonary disorder, affects countless individuals globally. Characterized by chronic inflammation of the bronchial passages, its symptoms include cough, wheezing, dyspnea, and chest tightness. While many manage their through pharmaceutical interventions self-care, significant subset grapples with severe asthma, posing therapeutic challenges. This study delves into intricate etiology emphasizing pivotal roles immune cells such as T cells, eosinophils, mast in...

10.1101/2024.04.15.589644 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-04-20

Objective: This study aimed to identify maternal circulating exosomal miRNAs as potential non-invasive biomarkers for the early detection of fetal ventricular septal defects (VSDs). Methods: In total, 182 pregnant women, comprising 91 VSD cases and matched controls, were included in this study. Exosomes isolated; dysregulated profiled using next-generation sequencing. Differential abundance was verified quantitative real-time polymerase chain reaction (qRT-PCR). Diagnostic accuracy evaluated...

10.3389/fgene.2021.717208 article EN cc-by Frontiers in Genetics 2021-09-09

Abstract Sooty moulds are a widespread group of saprophytic ascomycetes that obtain nutrients from honeydew excreted by sap‐feeding insects and coat plant tissue with mycelia. Research on sooty has focused fungal morphology phylogeny‐based taxonomy, but little research been conducted the community structure. In this study, PacBio sequencing platform was used to systematically analyse bacterial diversity mould camphor trees at two sampling sites. Six dominant genera were identified, which...

10.1111/1462-2920.16321 article EN Environmental Microbiology 2022-12-20

Asthma, a pervasive pulmonary disorder, affects countless individuals globally. Characterized by chronic inflammation of the bronchial passages, its symptoms include cough, wheezing, dyspnea, and chest tightness. While many manage their through pharmaceutical interventions self‐care, significant subset grapples with severe asthma, posing therapeutic challenges. This study delves into intricate etiology emphasizing pivotal roles immune cells such as T cells, eosinophils, mast in pathogenesis....

10.1155/2024/1218700 article EN cc-by Journal of Immunology Research 2024-01-01
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