A5072867541- Hypothalamic control of reproductive hormones
- Animal Behavior and Reproduction
- Animal Vocal Communication and Behavior
- Animal Nutrition and Physiology
- Regulation of Appetite and Obesity
- Marine animal studies overview
- Neuroendocrine regulation and behavior
- Neuropeptides and Animal Physiology
- Ovarian function and disorders
- Plant Reproductive Biology
- Language and cultural evolution
- Stress Responses and Cortisol
- Child and Animal Learning Development
- Plant and animal studies
- Sperm and Testicular Function
- Circadian rhythm and melatonin
- Insect and Arachnid Ecology and Behavior
- Reproductive Biology and Fertility
- Receptor Mechanisms and Signaling
- Primate Behavior and Ecology
- Bat Biology and Ecology Studies
- Estrogen and related hormone effects
- Growth Hormone and Insulin-like Growth Factors
Azabu University
2016-2025
Waseda University
2009-2017
Chiba University
2005-2011
RIKEN Center for Brain Science
2005-2011
Nippon Medical School
2010-2011
Abstract Gonadotropin-inhibitory hormone (GnIH) is a hypothalamic neuropeptide that inhibits gonadotropin secretion and socio-sexual behaviours. Oestrogen (neuroestrogen) synthesized in the brain from androgen by aromatase regulates male Here we show GnIH directly activates increases neuroestrogen synthesis preoptic area (POA) behaviours of quail. Aromatase activity concentration POA are low morning when birds active, but gradually until evening become inactive. Centrally administered...
Abstract The anatomical innovation of sound‐producing organs, which gives rise to a wide variety sound signals, is one the most fundamental factors leading explosive speciation modern birds. Despite being key clue resolving homology sound‐controlling muscles among birds, only few studies have explored embryonic development syringeal muscles. Using serial histological sections and immunohistochemistry, we described three‐dimensional anatomy cartilage, muscle, innervation pattern...
Several neuropeptides with the C-terminal RFamide sequence have been identified in hypothalamus of a variety vertebrates. Among peptide groups, however, only LPXRFamide peptides, including gonadotropin-inhibitory hormone, characterized avian brain. In present study, we sought for presence other peptides hypothalamus. We cDNA encoding an orthologous to 26RFa (also referred as QRFP) Japanese quail. The deduced quail precursor consisted 120-amino-acid residues, one 27 amino acids. This was...
Rapid effects of social interactions on transient changes in hormonal levels are known a wide variety vertebrate taxa, ranging from fish to humans. Although these responses mediated by the brain, neurochemical pathways that translate signals into reproductive physiological unclear. In this study, we analyzed how female presence modifies synthesis and/or release various neurochemicals, such as monoamines and neuropeptides, brain downstream hormones sexually active male Japanese quail. By...
Gonadotropin-inhibitory hormone (GnIH) was first identified in the Japanese quail as a hypothalamic neuropeptide inhibitor of gonadotropin secretion. Subsequent studies have shown that GnIH is present brains birds including songbirds, and mammals humans. The avian mammalian peptides universally possess an LPXRFamide (X = L or Q) motif at their C-termini. Mammalian are also designated RFamide-related from structures. receptor for G protein-coupled 147 (GPR147), which thought to be coupled Gαi...
Gonadotropin-inhibitory hormone (GnIH) has a well-established role in regulating reproductive functions, but recent data also demonstrated its involvement of the control metabolic processes. GnIH neurons and fibers have been identified hypothalamic regions associated with feeding behavior energy homeostasis receptors being expressed throughout hypothalamus. does not act alone hypothalamus, rather interacts melanotropin system as well other neuropeptides. are peripheral tissues involved...
Several neuropeptides with the C-terminal Arg-Phe-NH(2) (RFa) sequence have been identified in hypothalamus of a variety vertebrates. The present study was conducted to isolate novel RFa peptides from zebra finch brain. Peptides were isolated by immunoaffinity purification using an antibody that recognises avian peptides. peptide consisted 25 amino acids at its C-terminus. SGTLGNLAEEINGYNRRKGGFTFRFa. Alignment vertebrate 26RFa has revealed is 26RFa. We also cloned precursor cDNA encoding...
Bengalese finches, Lonchura striata, are extremely sexually dimorphic in their singing behavior; males sing complex songs, whereas females do not at all. This study describes the developmental differentiation of brain song system finches. Nissl staining was used to measure volumes four telencephalic nuclei: Area X, HVC, robust nucleus arcopallium (RA), and lateral portion magnocellular anterior nidopallium (LMAN). In juveniles (circa 35 days old), X HVC were well developed males, while they...
Biased mating due to female preferences towards certain traits in males is a major mechanism driving sexual selection, and may constitute an important evolutionary force organisms with reproduction. In birds, although the role of male ornamentation, plumage coloration, genetic dissimilarity, body size have on mate selection by females been examined extensively, few studies clarified exactly how these characteristics affect preferences. Here, we show that testosterone (T)-dependent...
Abstract The Bengalese finch was domesticated more than 250 years ago from the wild white‐rumped munia (WRM). Similar to other species, finches show a reduced fear response and have lower corticosterone levels, compared WRMs. munias also different song types. Since oxytocin ( OT ) has been found be involved in stress coping auditory processing, we tested whether sequence brain expression pattern content differ finches. We sequenced 10 11 identified intra‐strain variability both untranslated...
Gonadotrophin‐inhibitory hormone (GnIH) is a hypothalamic neuropeptide that inhibits gonadotrophin synthesis and release in birds mammals. In Japanese quail, GnIH neurones express the noradrenergic receptor receive innervation. Treatment with noradrenaline (NA) stimulates from diencephalic tissue blocks vitro . However, effects of NA on gene expression have not been determined. We investigated regulation brain male quail using selective neurotoxin N ‐(2‐chloroethyl)‐...
Bengalese Finches Lonchura striata var. domestica are extremely sexually dimorphic in their singing behavior; males sing complex songs, whereas females do not at all. The brain nuclei that control song many times larger than those are, except the lateral portion of magnocellular nucleus anterior nidopallium (LMAN), which comprises same volume both sexes. In this study, we examined connectivity LMAN female using a biotinylated dextran amine (BDA) vivo tracing technique. We found efferent...
Vasoactive intestinal peptide (VIP) treatment induced mRNA expression of Prolactin (PRL) in the chicken anterior pituitary gland. VIP responsive element (VRE) PRL promoter was identified various bird species. However, transcription factor, which binds to VRE, has not yet been identified. regulatory element-binding protein (PREB) gene cloned as a candidate factor VRE. Increases levels and PREB during embryogenesis were whether affects remains unknown. The effects forskolin on embryonic gland...