A5047193727- Antifungal resistance and susceptibility
- Pneumocystis jirovecii pneumonia detection and treatment
- Fungal Infections and Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Neutropenia and Cancer Infections
- Infective Endocarditis Diagnosis and Management
- Antibiotic Use and Resistance
- Parathyroid Disorders and Treatments
- Respiratory Support and Mechanisms
- School Health and Nursing Education
- Mechanical Circulatory Support Devices
- HIV/AIDS Research and Interventions
- Streptococcal Infections and Treatments
- Liver Disease and Transplantation
- Medical Imaging and Pathology Studies
- Renal function and acid-base balance
- Actinomycetales infections and treatment
- Respiratory and Cough-Related Research
- Vitamin C and Antioxidants Research
- Hemoglobinopathies and Related Disorders
- Intensive Care Unit Cognitive Disorders
- Surgical site infection prevention
- Surgical Sutures and Adhesives
- Syphilis Diagnosis and Treatment
- HIV/AIDS drug development and treatment
University of Washington
2021-2024
Beth Israel Deaconess Medical Center
2019-2021
Washington University in St. Louis
2017-2019
Candida infective endocarditis (CIE) is a rare but serious complication of candidemia. Incidence and risk factors associated with CIE among candidemic patients are poorly defined from small cohorts. Identification clinical predictors this entity may guide more judicious use cardiac imaging. We conducted retrospective analysis all inpatients aged ≥18 years diagnosed candidemia at our institution. was by fulfilling two the major Duke criteria: specifically vegetation(s) on echocardiogram...
Thiamine supplementation is recommended for patients with alcohol use disorder (AUD). The authors hypothesize that critically ill AUD are commonly not given thiamine supplementation.To describe incidence in and various critical illnesses (alcohol withdrawal, septic shock, traumatic brain injury [TBI], diabetic ketoacidosis [DKA]) the United States.Retrospective observational study.Cerner Health Facts database.Adult a diagnosis of who were admitted to intensive care unit TBI, or DKA between...
Summary Candidaemia is the most common clinical presentation of invasive candidiasis and a major cause morbidity mortality. Candiduria predictor for candidaemia; however, patient characteristics that are associated with concurrent candidaemia in setting candiduria unclear. Identifying these could aid early detection systemic disease. We performed retrospective cohort analysis hospitalised patients at our institution over 13‐year period. Our evaluation included demographics, comorbidities,...
Candida krusei bloodstream infection (CK BSI) is associated with high mortality, but whether this due to underlying comorbidities in affected patients or the organism itself unknown. Identifying patient characteristics that are CK BSI crucial for clinical decision-making and prognosis.We conducted a retrospective analysis of hospitalized at our institution between 2002 2015. Data were collected on demographics, comorbidities, medications, procedures, central lines, vital signs, laboratory...
Abstract Background Candida krusei (CK) candidemia is associated with high mortality, but whether this due to underlying comorbidities in affected patients or the organism itself unknown. We analyzed factors C. and its outcomes. Methods A retrospective analysis of hospitalized was conducted at our institution between 2002 2015. Data were collected on demographics, comorbidities, medications, procedures, central lines, vital signs, labs. Univariable logistic Cox regression used identify...
Abstract Background An infectious diseases (ID) consultation is often, but not always, obtained to help guide treatment of patients with candidemia. We examined if ID affected patient outcome in culture positive Methods assembled a retrospective cohort 1,873 cases candidemia hospitalized our academic tertiary care hospital from 2002 2015. collected data on comorbidities, predisposing factors; antifungal therapy, survival and consult. Patients who died within 24 hours diagnosis were excluded,...
We present the case of a 58-year-old man who presented with dyspnea, cough, and weight loss was ultimately diagnosed pulmonary amyloidosis multiple myeloma. Diagnosis achieved lung biopsy which showed AL amyloid deposits involving interstitium, vessels, airway. He treated cyclophosphamide, bortezomib, dexamethasone but died prior to completing treatment. His is unique for deposition found in all three compartments clear pathophysiologic manifestations each compartment, rapid disease...
Abstract Background Botswana was the first African country to implement a ‘treat all’ dolutegravir (DTG)-based treatment program for all adults. We studied whether this transition made short-term impact on inpatient mortality among people living with HIV (PLWHIV). Methods From Dec 2015-Nov 2017, data were collected prospectively patients admitted medical wards of district hospital in Botswana. Tenofovir/emtricitabine/efavirenz (TDF/FTC/EFV) first-line recommended antiretroviral (ART) regimen...
Abstract Background Increased incidence of Candida glabrata (CG) infection is a growing concern in recent years due to the higher rates fluconazole resistance associated with C. . This study aimed create risk predictive model for patients culture-positive candidemia. Methods Demographic data, factors, laboratory parameters, and outcomes were retrospectively collected on all cases candidemia occurring at large tertiary referral hospital between January 2002 2015. Between-group differences...
Candida bloodstream infection (CBSI) is associated with high morbidity and mortality. Guidelines recommend echinocandins as initial therapy, fluconazole an acceptable alternative in selected patients, including those at low risk for resistance. We aimed to create a predictive model identify patient of performed retrospective analysis hospitalized patients CBSI large tertiary referral hospital between January 2007 2015. Data were collected on demographics, comorbidities, medications,...
Abstract Background Candida endocarditis (CE) is a rare but an invasive infection associated with high mortality rate. The current understanding of this poorly defined from case reports, series and small cohorts. This study aimed to assess the risk factors for CE in patients candida bloodstream infections (CBSI). Methods We conducted retrospective analysis all hospitalized diagnosed CBSI at large tertiary care hospital between 2002 2015. Data included demographics, comorbidities, laboratory...
We present the case of a 58-year-old man who presented with dyspnea, cough, and weight loss was ultimately diagnosed pulmonary amyloidosis multiple myeloma. Diagnosis achieved lung biopsy which showed AL amyloid deposits involving interstitium, vessels, airway. He treated cyclophosphamide, bortezomib, dexamethasone but died prior to completing treatment. His is unique for deposition found in all three compartments clear pathophysiologic manifestations each compartment, rapid disease...