John Oropello

ORCID: 0000-0003-4467-3584
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About
Contact & Profiles
Research Areas
  • Hemodynamic Monitoring and Therapy
  • Cardiac, Anesthesia and Surgical Outcomes
  • Ultrasound in Clinical Applications
  • Central Venous Catheters and Hemodialysis
  • Sepsis Diagnosis and Treatment
  • Respiratory Support and Mechanisms
  • Renal function and acid-base balance
  • Intensive Care Unit Cognitive Disorders
  • Airway Management and Intubation Techniques
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Vascular Procedures and Complications
  • Tracheal and airway disorders
  • Cardiac Arrest and Resuscitation
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Venous Thromboembolism Diagnosis and Management
  • Non-Invasive Vital Sign Monitoring
  • Liver Disease and Transplantation
  • Appendicitis Diagnosis and Management
  • Acute Kidney Injury Research
  • Electrolyte and hormonal disorders
  • Palliative Care and End-of-Life Issues
  • Abdominal Surgery and Complications
  • Congenital Diaphragmatic Hernia Studies
  • Pleural and Pulmonary Diseases
  • Family and Patient Care in Intensive Care Units

Icahn School of Medicine at Mount Sinai
2016-2025

Mount Sinai Hospital
1994-2024

Mount Sinai Hospital
2016-2024

Mount Sinai Hospital
1992-2024

Sinai Hospital
2012-2022

Mount Sinai Medical Center
1997-2020

Pulmonary and Critical Care Associates
2017

Vanderbilt University Medical Center
2017

Augusta University
2017

Baylor College of Medicine
2017

Pulmonary hypertension is common in critical care settings and presence of right ventricular failure challenging to manage. pregnant patients carries a high mortality rates between 30–56%. In the past decade, new treatments for pulmonary have emerged. Their application women with may hold promise reducing morbidity mortality. Signs symptoms are nonspecific women. Imaging workup undesirable radiation exposure. artery catheter remains gold standard diagnosing hypertension, although its use...

10.1155/2012/709407 article EN cc-by Pulmonary Medicine 2012-01-01

ABSTRACT Background Major Adverse Kidney Events within 30 days (MAKE30) is an important patient-centered outcome for assessing the impact of acute kidney injury (AKI). The existing prediction models MAKE30 are static and overlook dynamic changes in clinical status. In this study, we introduce ORAKLE, a novel deep-learning model that utilizes evolving time-series data to predict MAKE30, enabling personalized, approaches AKI management improvement. Methods We conducted retrospective study...

10.1101/2025.01.18.25320769 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2025-01-19

NEUROSURGICAL PATIENTS ARE at high risk for the development of thrombosis and thromboembolism. We compared perioperative clotting factor coagulation parameters 20 patients undergoing elective craniotomy brain tumors to those abdominal surgery. also measured levels plasma arginine vasopressin determine if changes in this hormone might be associated with factors, activated partial thromboplastin times, or bleeding times. The results demonstrated a significant reduction times neurosurgery...

10.1227/00006123-199403000-00001 article EN Neurosurgery 1994-03-01

To study the early postoperative intensive care unit (ICU) management and complications in first 2 wk of patients undergoing cytoreductive surgery (CRS) hyperthermic intraperitoneal chemotherapy (HIPEC).Our is a retrospective, observational performed at Icahn School Medicine Mount Sinai, quaternary hospital New York City. All adult who underwent CRS HIPEC between January 1, 2007 December 31, 2012 admitted to ICU postoperatively were studied. Fifty-one came out 170 therapy during period. Data...

10.5492/wjccm.v6.i2.116 article EN cc-by-nc World Journal of Critical Care Medicine 2017-01-01

Objective: To compare the effects of hypertonic saline, sodium bicarbonate, and Carbicarb® resuscitation on acid-base balance, hemodynamics, oxygen dynamics in a reperfused, canine hemorrhagic shock model. Design: Prospective, randomized trial. Setting: Laboratory at university medical center. Subjects: Thirty-five anesthetized, mongrel dogs. Interventions: After administration anesthesia, dogs were intubated mechanically ventilated. Vascular catheters inserted into each femoral artery, for...

10.1097/00003246-199410000-00018 article EN Critical Care Medicine 1994-10-01

BENJAMIN, ERNEST MD, FCCM; POLOKOFF, ELLEN MD; OROPELLO, JOHN M. LEIBOWITZ, ANDREW B. IBERTI, THOMAS J. FCCM Author Information

10.1097/00003246-199208000-00019 article EN Critical Care Medicine 1992-08-01

A 54-year-old man, with a history of poorly controlled diabetes mellitus, presented to the emergency room three-day severe, progressive swelling his neck associated odynophagia. Oral cavity examination was remarkable for trismus mouth opening limited two fingers, edematous floor mouth, drooling and carious second lower molar tooth. Physical exam consistent bilateral neck, severe tenderness symmetric induration in submandibular area Ludwig's angina. On admission, leukocyte count 7300/μL...

10.1016/j.idcr.2016.03.001 article EN cc-by-nc-nd IDCases 2016-01-01

Serial brain SPECT imaging was performed on patients after subarachnoid hemorrhage and surgical clipping of intracranial aneurysms. A total 20 HMPAO scans were 9 in whom clinical vasospasm did not develop. Areas diminished regional cerebral blood flow (rCBF) found near the operative site 17 studies, which correlate with patients' neurologic condition suggestive postoperative edema. Brain has a potentially valuable role to play evaluation susceptible vasospasm; however, it is important be...

10.1097/00003072-199407000-00006 article EN Clinical Nuclear Medicine 1994-07-01

Arterial catheter placement for hemodynamic monitoring is commonly performed in critically ill patients. The radial and femoral arteries are the two sites most frequently used; there limited data on use of axillary artery this purpose. aim study was to investigate rate complications from ultrasound-guided

10.1177/08850666241257417 article EN Journal of Intensive Care Medicine 2024-05-25

Abstract Purpose Intravenous fluids are mainstay of management acute kidney injury (AKI) after sepsis but can cause fluid overload. Recent literature shows that restrictive strategy may be beneficial in some patients with AKI, however, identifying these is challenging. We aimed to develop and validate a machine learning algorithm identify who would benefit from strategy. Methods included developed AKI within 48 hours ICU admission defined as receiving <500mL 24 AKI. Our primary outcome...

10.1101/2024.08.06.24311556 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-08-07
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