A5090382122- Regulation of Appetite and Obesity
- melanin and skin pigmentation
- Cardiovascular Disease and Adiposity
- Adipose Tissue and Metabolism
- Endoplasmic Reticulum Stress and Disease
- Sports Performance and Training
- Cardiovascular Effects of Exercise
- Autophagy in Disease and Therapy
- Atherosclerosis and Cardiovascular Diseases
- Genetics and Physical Performance
- thermodynamics and calorimetric analyses
- Myofascial pain diagnosis and treatment
- Cardiovascular Function and Risk Factors
- Shoulder Injury and Treatment
- Circular RNAs in diseases
- Genetic Neurodegenerative Diseases
- Liver Disease Diagnosis and Treatment
- Genetics and Neurodevelopmental Disorders
- Glycogen Storage Diseases and Myoclonus
- Diabetic Foot Ulcer Assessment and Management
- RNA regulation and disease
- Parkinson's Disease Mechanisms and Treatments
- Cellular Mechanics and Interactions
- Tendon Structure and Treatment
- Angiogenesis and VEGF in Cancer
University of Auckland
2021-2024
University of Otago
2017-2021
Manchester Metropolitan University
2016
Genomics (United Kingdom)
2016
We aimed to quantify the ACE I/D and ACTN3 R577X (rs1815739) genetic variants in elite rugby athletes (rugby union league) compare genotype frequencies controls between playing positions. The athlete cohort consisted of 507 Caucasian men, including 431 that for some analyses were divided into backs forwards specific positional groups: front five, back row, half backs, centers, three. Controls 710 men women. Real-time PCR genomic DNA was used determine genotypes using TaqMan probes groups...
Glycogen-autophagy ('glycophagy') is a selective autophagy process involved in delivering glycogen to the lysosome for bulk degradation. Glycophagy protein intermediaries include STBD1 as tagging receptor, cargo into forming phagosome by partnering with Atg8 homolog, GABARAPL1. emerging key of energy metabolism and development reliable tools assessment glycophagy activity an important priority. Here we show that antibodies raised against N-terminus GABARAPL1 (but not full-length protein)...
Abstract Type 2 diabetes is a prominent risk factor for peripheral artery disease (PAD). Yet, the mechanistic link between and PAD remains unclear. This study proposes that dysregulation of endogenous hormone ghrelin, potent modulator vascular function, underpins causal PAD. Moreover, this aimed to demonstrate therapeutic potential exogenous ghrelin in diabetic mouse model Standard ELISA analysis was used quantify compare circulating levels (i) human patients with or without (clinic) (ii)...
Increased heart size is a major risk factor for failure and premature mortality. Although abnormal growth subsequent to hypertension often accompanies disturbances in mechano-energetics cardiac efficiency, it remains uncertain whether hypertrophy their primary driver. In this study, we aimed investigate the direct association between using isolated left-ventricular trabeculae from rat model of its control. We evaluated energy expenditure (heat output) mechanical performance (force length...
Glycogen-autophagy ('glycophagy') is a selective autophagy process involved in delivering glycogen to the lysosome for bulk degradation. Glycophagy protein intermediaries include STBD1 as tagging receptor, cargo into forming phagosome by partnering with Atg8 homolog, GABARAPL1. emerging key of energy metabolism and development reliable tools assessment glycophagy activity an important priority. Here we show that antibodies raised against N-terminus GABARAPL1 (but not full-length protein)...
Abstract Background: Type 2 diabetes is a prominent risk factor for peripheral artery disease (PAD). Yet, the mechanistic link between and PAD remains unclear. This study proposes that dysregulation of endogenous hormone ghrelin, potent modulator vascular function, underpins causal PAD. Moreover, this aimed to demonstrate therapeutic potential exogenous ghrelin in diabetic mouse model Methods: Standard ELISA analysis was used quantify compare circulating levels i) human patients with or...