- Microfluidic and Capillary Electrophoresis Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Microfluidic and Bio-sensing Technologies
- 3D Printing in Biomedical Research
- Biosensors and Analytical Detection
- Electrowetting and Microfluidic Technologies
- Electrohydrodynamics and Fluid Dynamics
- Nanopore and Nanochannel Transport Studies
- Nanofabrication and Lithography Techniques
- Heat Transfer and Boiling Studies
- Material Properties and Applications
- Perovskite Materials and Applications
- Advanced Biosensing Techniques and Applications
- Glass properties and applications
- bioluminescence and chemiluminescence research
- Additive Manufacturing and 3D Printing Technologies
- Surface Roughness and Optical Measurements
- Force Microscopy Techniques and Applications
- Fluid Dynamics and Heat Transfer
- Material Science and Thermodynamics
- Advanced Photocatalysis Techniques
- Quantum Dots Synthesis And Properties
- Diatoms and Algae Research
- Injection Molding Process and Properties
- Engineering Technology and Methodologies
Institute for Analytical Instrumentation
2015-2024
Roche (Switzerland)
2022
Abbott (Sweden)
2022
Saint Petersburg Academic University
2011-2018
ITMO University
2011-2018
Siberian Federal University
2017
Moscow Power Engineering Institute
2016
Russian Academy of Sciences
2008-2015
Abstract Nowadays droplet microfluidics is widely used to perform high throughput assays and for the synthesis of micro- nanoparticles. These applications usually require packaging several reagents into droplets their mixing start a biochemical reaction. For rapid microfluidic devices additional functional elements that make designs more complex. Here we series 2D numerical simulations, followed by experimental studies, introduce novel asymmetric flow-focusing generator, which enhances...
Chemically synthesized inorganic lead halide perovskite lasers based on nanostructures, generating coherent light at room temperature, and having a low threshold, have become powerful tools for various photonic applications. However, to fabricate high-quality nanostructures substrate, it is crucial provide certain surface parameters precisely keep synthesis conditions. Here, we report novel approach the one-step fabrication of CsPbBr3 nanolasers in form suspension obtained by rapid...
Droplet microfluidics is an extremely useful and powerful tool for industrial, environmental, biotechnological applications, due to advantages such as the small volume of reagents required, ultrahigh-throughput, precise control, independent manipulations each droplet. For generation monodisperse water-in-oil droplets, usually T-junction flow-focusing microfluidic devices connected syringe pumps or pressure controllers are used. Here, we investigated droplet-generation regimes in a device...
Solid-state nanopore devices with plasmonic nanoantennas are powerful tools that allow for working individual particles and molecules in solution as well providing light-induced control of ionic current flow through them. However, the manipulation by light still requires high power densities and, thus, results optical heating nanopore. Here, we solve this problem using a 5 nm gap bow-tie nanoantenna on SiNx membrane irradiated broadband spectrum incident light. In regime, photons not only...
The aim of this work was to determine a design microfluidic droplet generator which provides the best mixing two components within during its formation. Simulation droplets' formation in various designs generators performed. Dependences index from capillary number and viscosity continuous phase were obtained for each design. determined directly after droplet. It found that small numbers correspond lower due increase droplets diameter. high vortex flows area leads an asymmetric designs, but...
Microfluidics is a rapidly growing area that provides innovations in biotechnology, medical diagnostics, and life science. Along with the commercial solutions, there are open-source projects aimed to make such technologies more affordable flexible for end users. In this article, we developed an open-source, low-cost, easy-to-use microfluidic pressure controller modular design based on electropneumatic regulators introduce liquids into devices under constant pressures. For implementation of...
The rapid detection of pollutants in water can be performed with enzymatic probes, the catalytic light-emitting activity which decreases presence many types pollutants. Herein, we present a microfluidic system for continuous chemoenzymatic biosensing that generates emulsion droplets containing two enzymes bacterial bioluminescent (luciferase and NAD(P)H:FMN-oxidoreductase) substrates required reaction. developed chip "water-in-oil" volume 0.1 μL frequency up to 12 drops per minute as well...
Polycarbonate and polypropylene microchips were made by thermoforming sealed special PCR films. The aim of this work was to study the possibility promptly manufacturing for performing RT-PCR analysis. Microchips are hard plastics, preferably using domestically produced materials. Therefore, achieve goal, following tasks set: 1) topology chambers in polycarbonate master mold laser microforming; 2) sealing obtained with commercial films PCR, which polymer a thin adhesive layer (the connection...
Parameters for sample introduction, dried reagents dissolution and mixing with bienzyme system NAD(H):FMN‐oxidoreductase luciferase immobilised in microfluidic chip were successfully determined. Numerical simulations of reaction chamber geometry, flavin mononucleotide (FMN) escape from starch gel options conducted to achieve higher sensitivity bioluminescent reaction. Results numerical verified experimentally. The active mixer was made an electro‐mechanical speaker's membrane which connected...
In this paper was demonstrated the possibility of use FAB mass spectrometry on an impulse spectrometer VG-70 SEQ ("Fisons VG Analytical", USA) for study biosynthetic pathways 2 H-labeled purine ribonucleoside inosine secreted into liquid culture (LC) by Gram-positive chemoheterotrophic bacterium Bacillus subtilis VKPM B-3157 when grown heavy water (HW) medium with % hydrolyzate deuterated biomass methylotrophic Brevibacterium methylicum B-5662 as a source growth substrates.Isolation from LC...