A5057243449- Bone Tissue Engineering Materials
- Graphene and Nanomaterials Applications
- Nanoparticles: synthesis and applications
- Dental Implant Techniques and Outcomes
- Dental materials and restorations
- Advanced Nanomaterials in Catalysis
- Oral microbiology and periodontitis research
- Orthopaedic implants and arthroplasty
- Nanoparticle-Based Drug Delivery
- biodegradable polymer synthesis and properties
- Electrospun Nanofibers in Biomedical Applications
- Bone health and treatments
- Endodontics and Root Canal Treatments
- Calcium Carbonate Crystallization and Inhibition
- Wound Healing and Treatments
- Diverse Scientific Research Studies
- Mesoporous Materials and Catalysis
- Erythrocyte Function and Pathophysiology
- Nanocluster Synthesis and Applications
- Advanced Drug Delivery Systems
- Ferroelectric and Piezoelectric Materials
- Research on Leishmaniasis Studies
- Diamond and Carbon-based Materials Research
- Tissue Engineering and Regenerative Medicine
- Inflammatory Biomarkers in Disease Prognosis
Aristotle University of Thessaloniki
2019-2024
Hemocompatible nanoparticles with reactive oxygen species (ROS) scavenging properties for titanium implant surface coatings may eliminate failure related to inflammation and bacterial invasion. Cerium (Ce) is a rare earth element, that belongs the lanthanide group. It exists in two oxidation states, Ce+3 Ce+4, which contribute antioxidant, catalytic, antibacterial, ROS-scavenging properties. The purpose of present study was synthesize ceria evaluate their hemocompatibility ROS synthesis...
Mesoporous silica-based nanoparticles (MSNs) are considered promising drug carriers because of their ordered pore structure, which permits high loading and release capacity. The dissolution Si Ca from MSNs can trigger osteogenic differentiation stem cells towards extracellular matrix calcification, while Mg Sr constitute key elements bone biology metabolism. aim this study was the synthesis characterization sol–gel-derived co-doped with Ca, Sr. Their physico-chemical properties were...
(1) Background: An element that has gained much attention in industrial and biomedical fields is Cerium (Ce). CeO2 nanoparticles have been proven to be promising regarding their different applications for the control of infection inflammation. The aim present study was investigate biological properties antimicrobial behavior cerium oxide (CeO2) (NPs). (2) Methods: investigation NPs’ biocompatibility with human periodontal ligament cells (hPDLCs) evaluated via MTT assay. Measurement alkaline...
Engineered electrospun membranes have emerged as promising materials in guided tissue regeneration, they provide an appropriate framework for the formation of new functional periodontal tissues. The development multifunctional local drug delivery systems with sustained release drugs prolonged infection control can be used surgical interventions to simultaneously prohibit epithelium downgrowth and ensure proper healing regeneration damaged aim present study was fabrication novel composite...
(1) Background: A proposed approach to promote periodontal tissue regeneration in cases of peri-implantitis is the local administration growth factors at implant site. Recombinant human bone morphogenetic protein-2 (rh-BMP-2) can effectively and osseointegration development appropriate carriers for its delivery paramount importance. The aim present study was develop SBA-15 mesoporous nanoparticles (MSNs) with varying porosity, evaluate their biocompatibility Periodontal Ligament Cells...
Silica-based ceramics doped with calcium and magnesium have been proposed as suitable materials for scaffold fabrication. Akermanite (Ca2MgSi2O7) has attracted interest bone regeneration due to its controllable biodegradation rate, improved mechanical properties, high apatite-forming ability. Despite the profound advantages, ceramic scaffolds provide weak fracture resistance. The use of synthetic biopolymers such poly(lactic-co-glycolic acid) (PLGA) coating improves performance tailors their...
Ion doping has rendered mesoporous structures important materials in the field of tissue engineering, as apart from drug carriers, they can additionally serve regenerative materials. The purpose present study was synthesis, characterization and evaluation effect artemisinin (ART)-loaded cerium-doped calcium silicate nanopowders (NPs) on hemocompatibility cell proliferation human periodontal ligament fibroblasts (hPDLFs). Mesoporous NPs were synthesized a basic environment via surfactant...
Yttria-stabilized zirconia nanoparticles can be applied as fillers to improve the mechanical and antibacterial properties of luting cement. The aim this study was synthesize yttria-stabilized by sol-gel method investigate their composition, structure, morphology biological properties.Nanopowders ZrO2 7 wt% Y2O3 (nY-ZrO) were synthesized sintered at three different temperatures: 800, 1000 1200 °C, size investigated. biocompatibility investigated with human gingival fibroblasts (hGFs), while...
Aliphatic polyesters are widely used for biomedical, pharmaceutical and environmental applications due to their high biodegradability cost-effective production. Recently, star hyperbranched based on glycerol ω-carboxy fatty diacids have gained considerable interest. Succinic acid bio-based similar regarded as safe materials according the US Food Drug Administration (FDA). Bioactive glass scaffolds utilized in bone tissue engineering relatively brittle materials. However, mechanical...
A promising strategy to enhance bone regeneration is the use of bioactive materials doped with metallic ions therapeutic effects and their combination active substances and/or drugs. The aim present study was investigate osteogenic capacity human periodontal ligament cells (hPDLCs) in culture artemisinin (ART)-loaded Ce-doped calcium silicate nanopowders (NPs); Methods: Mesoporous silica, calcium-doped calcium/cerium-doped NPs were synthesized via a surfactant-assisted cooperative...
Malaria and Leishmaniasis are two major parasitic diseases, endemic in large areas of tropical countries with high morbidity mortality across the world. Nanoparticles small sizes specifically considered medicine due to their ability enter cells, control distribution administered drug carry place action. The present study aims introduce application silica nanoparticles as new promising nanotools malaria leishmaniasis treatment. Ion doped nanomaterials revealed antileishmanial activities...
Nanotechnology has a great potential to improve biomaterials used in tissue engineering. Nano-bioceramics are preferable compared their micro-scale counterparts, because of increased surface area, improving both mechanical properties and apatite-forming ability due the nucleation sites provided. Elements such as Si, Ca Mg for synthesis bioglasses have significant effect on bone metabolism, they particularly important regeneration this type glasses present high residual glassy phase, hardness...
Glass-ceramic nanopowder with a composition of 55SiO2-35CaO-10MgO (mol %) was synthesized by the sol–gel method and heat treated at three temperatures (T1 = 835 °C, T2 1000 T3 1100 °C) in order to obtain different materials (C1, C2, C3, respectively) varying crystal structure. Bioactivity oxidative stress were evaluated simulated body fluid (SBF) for various time periods (up 10 days). The structure their apatite-forming ability investigated X-ray diffractometry (XRD), Fourier transform...
The nature of the surface is critical in determining biological activity silica powders. A novel correlation between toxicity and properties bioactive glass ceramics (BGCs) synthesized via sol-gel method was attempted this study. behavior BGCs after their attachment to red blood cells (RBCs) evaluated toxic effects were determined based on hemolysis, membrane injury anti-phosphotyrosine immunoblot Band 3, lipid peroxidation, potential generate reactive oxygen species, antioxidant enzyme...
(1) Background: The presence of various dental ceramic materials with different chemical compositions complicates clinicians’ decision making, especially in cases a highly acidic environment appearing patients suffering from gastroesophageal reflux disease or other eating disorders. Thermal alterations the oral cavity can also affect surface structure and roughness, resulting variations both degradation mechanisms and/or bacteria adhesion. aim present vitro study was to evaluate effect...