A5019469712- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metal complexes synthesis and properties
- Synthesis and Characterization of Heterocyclic Compounds
- Nanoparticles: synthesis and applications
- RNA Interference and Gene Delivery
- Analytical chemistry methods development
- Analytical Chemistry and Chromatography
- Graphene and Nanomaterials Applications
- Click Chemistry and Applications
- Organometallic Compounds Synthesis and Characterization
- PI3K/AKT/mTOR signaling in cancer
- biodegradable polymer synthesis and properties
- Antimicrobial agents and applications
- Bone and Dental Protein Studies
- Advanced biosensing and bioanalysis techniques
- Fermentation and Sensory Analysis
- TGF-β signaling in diseases
- Brucella: diagnosis, epidemiology, treatment
- Polysaccharides and Plant Cell Walls
- Bone Tissue Engineering Materials
- Hemophilia Treatment and Research
- Nanoparticle-Based Drug Delivery
- Phytochemicals and Antioxidant Activities
- 3D Printing in Biomedical Research
Aristotle University of Thessaloniki
2014-2024
(1) Background: An element that has gained much attention in industrial and biomedical fields is Cerium (Ce). CeO2 nanoparticles have been proven to be promising regarding their different applications for the control of infection inflammation. The aim present study was investigate biological properties antimicrobial behavior cerium oxide (CeO2) (NPs). (2) Methods: investigation NPs’ biocompatibility with human periodontal ligament cells (hPDLCs) evaluated via MTT assay. Measurement alkaline...
Oregano essential oil (OEO), due to its wide variety of biological activities, could be a "green" alternative chemical preservatives. On the other hand, difficulties in use or storage have turned researchers' interest encapsulation strategies as way face stability and handling issues. Fabrication OEO-loaded particles, using nano spray drying technique (NSD) whey protein isolate-maltodextrin mixtures (1:1, 1:3) wall materials appears novel promising strategy. The obtained particles were...
Mini-emulsion polymerization was applied for the synthesis of cross-linked polymeric nanoparticles comprised methyl methacrylate (MMA) and Triethylene Glycol Dimethacrylate (TEGDMA) copolymers, used as matrix-carriers hosting D-limonene. D-limonene selected a model essential oil, well known its pleasant odor enhanced antimicrobial properties. The synthesized particles were assessed their morphology geometric characteristics by Dynamic Light Scattering (DLS) Scanning Electron Microscopy...
The aim of this investigation was to prepare novel hybrid materials with enhanced antimicrobial properties be used in food preservation and packaging applications. Therefore, nanocomposite were synthesized based on two stimuli-responsive oligo(ethylene glycol methacrylate)s, namely PEGMA PEGMEMA, the first bearing hydroxyl side groups three different metal nanoparticles, i.e., Ag, TiO2 ZnO. situ radical polymerization technique employed ensure good dispersion nanoparticles polymer matrix....
Anthocyanins are a group of phenolic compounds with great importance, not only because they play crucial role in wine’s quality, but also due to the fact that can have beneficial effects on human health. In this work, method was developed for detection and identification these solid wastes wine-making industry (red grape skins pomace), using liquid-liquid extraction (LLE) prior liquid chromatography-mass spectrometry technique (LC-MS). The complete process investigated optimized, starting...
Recently, miRNAs have been established as promising, specific biomarkers for the diagnosis of many diseases, including osteoarthritis. Herein, we report a ssDNA-based detection method implicated in osteoarthritis, specifically, miR-93 and miR-223. In this study, gold nanoparticles (AuNPs) were modified with oligonucleotide ssDNA to detect circulating blood healthy subjects patients suffering from The was based on colorimetric spectrophotometric assessment biofunctionalized AuNPs upon...
SARS-CoV-2 ORF3a accessory protein was found to be involved in virus release, immunomodulation and exhibited a pro-apoptotic character. In order unravel potential ORF3a-induced apoptotic inflammatory death mechanism, lung epithelial cells (A549) were transfected with vitro synthesized mRNA. The protein's dynamic involvement as "stress factor" for the endoplasmic reticulum, causing activation of PERK kinase other UPR-involved proteins therefore upregulation their signaling pathway...
Nanotechnology, the manipulation of matter on atomic, molecular, and supramolecular scales, has become most appealing strategy for biomedical applications is great interest as an approach to preventing microbial risks. In this study, we utilize antimicrobial performance drug-loading ability novel nanoparticles based silicon oxide strontium-substituted hydroxyapatite develop nanocomposite films a poly(l-lactic acid) (PLLA) polymer. We also demonstrate that nanoimprint lithography (NIL),...
We aimed to investigate whether the presence of mannose binding lectin (MBL2), ficolin 2 (FCN2) polymorphisms or combined deficiency significantly influence risk and subsequently frequency chemotherapy-induced bacterial infections in children with B acute lymphoblastic leukemia (B-ALL).MBL2 for exon 1 FCN2 promoter regions -986, -602, -557, -64, -4 8 +6,359, +6,424 were determined B-ALL. haplotype was by gene sequencing. Number duration FN episodes as well number recorded during induction...
In recent years, there has been an increasing interest in the study of Ag(I) coordination compounds as potent antibacterial and anticancer agents. Herein, a series complexes bearing phosphines heterocyclic thioamide ligands with highly electronegative NH2- CF3-group substituents, i.e. [AgCl(atdztH)(xantphos)] (1), [Ag(μ-atdztH)(DPEphos)]2(NO3)2 (2), [Ag(atdzt)(PPh3)3] (3), [Ag(μ-atdzt)(DPEphos)]2 (4), [Ag(μ-mtft)(DPEphos)]2 (5), where atdztH = 5-amino-1,3,4-thiadiazole-2-thiol, mtftH...
The great demand for antibacterial, biocompatible, and easily manufactured nanostructures has led to the design development of graphene-wrapped copper nanoparticles (CuNPs) supported on Si wafers. In this study, we investigated antibacterial properties graphene/CuNPs against Gram-positive Gram-negative bacteria. Additional experiments regarding behavior mouse fibroblast cell line L929 indicated their biocompatibility consequently render them as model biomaterials medical uses....