- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- Pregnancy and preeclampsia studies
- Liver Diseases and Immunity
- Liver physiology and pathology
- Medical Research and Treatments
- Birth, Development, and Health
- Hepatitis C virus research
- Growth Hormone and Insulin-like Growth Factors
- Gastrointestinal disorders and treatments
- Parasites and Host Interactions
- Reproductive System and Pregnancy
- RNA modifications and cancer
- Comparative Animal Anatomy Studies
- Gout, Hyperuricemia, Uric Acid
- Ureteral procedures and complications
- Genetics and Physical Performance
- Nutrition, Health and Food Behavior
- Congenital Diaphragmatic Hernia Studies
- Cytomegalovirus and herpesvirus research
- High Altitude and Hypoxia
- IL-33, ST2, and ILC Pathways
- Toxoplasma gondii Research Studies
- Pharmacovigilance and Adverse Drug Reactions
First Affiliated Hospital of Nanchang University
2025
Nanchang University
2025
The First Affiliated Hospital, Sun Yat-sen University
2021-2024
Sun Yat-sen University
2011-2024
Jiaxing University
2024
Second Military Medical University
2022
Peking University
2018-2022
PLA Academy of Military Science
2020-2022
Peking University People's Hospital
2022
First Affiliated Hospital of Zhengzhou University
2021
In Brief Study Design. We conducted a prospective cohort study of 448 patients with spinal metastases from variety cancer groups. Objective. To determine the specific predictive value Tokuhashi scoring system (T12) and its revised version (T15) in various primary tumors. Summary Background Data. The life expectancy is one most important factors selecting treatment modality. et al formulated prognostic total sum 12 points for preoperative prediction 1990 it 2005 to 15 points. There lack...
Aims/Background The Geriatric Nutritional Risk Index (GNRI) is an effective tool for identifying malnutrition, and helps monitor the prognosis of patients undergoing maintenance hemodialysis. However, association between GNRI cardiovascular or all-cause mortality in hemodialysis remains unclear. Therefore, this study investigated correlation with Methods This included 402 incident patients. Based on first-dialysis quartile, were divided into four groups: N1 (GNRI ≤85.04), N2 85.05–91.04), N3...
Bacterial biofilm infections of implantable medical devices decrease the effectiveness antibiotics, creating difficult-to-treat chronic infections. Prosthetic joint (PJI) are particularly problematic because they require prolonged antibiotic courses and reoperations to remove replace infected prostheses. Current models study PJI focus on Gram-positive bacteria, but Gram-negative (GN-PJI) increasingly common often more difficult treat, with worse clinical outcomes. Herein, we sought develop a...
AIM:To explore the value of liver fibrosis assessment by acoustic radiation force impulse (ARFI) and AST/ PLT ratio index (APRI) in chronic hepatitis C patients. METHODS:One hundred twenty eight patients with were examined using ARFI elastometry APRI, calculated according to known formulae.The gold standard biopsy was referred; ROC curve analysis used assess all APRI values.The corresponding cut-off values, sensitivities, specificities compared.In addition, correlation stages measurements...
Background: The accurate assessment of liver fibrosis is essential for patients with chronic disease. A biopsy an invasive procedure that has many potential defects and complications. Therefore, noninvasive techniques are considerable value clinical diagnosis. Liver spleen magnetic resonance elastography (MRE) serum markers have been proposed quantitative fibrosis. This study aims to compare the diagnostic performance stiffness measured by MRE, index based on 4 factors (FIB-4), aspartate...
Dementia is a global public health challenge. Certain medications, such as anticholinergics and benzodiazepines, have been linked to an increased dementia risk. However, most studies focused on limited range of drugs, lacking comprehensive overview. This article addressed this gap by analyzing drugs associated with using data from the FDA Adverse Event Reporting System (FAERS).
To perform a comparative assessment of the performance FibroTouch and FibroScan in patients with hepatitis B.A total 211 B, including cases chronic B (CHB) compensated cirrhosis, were enrolled for study between June November 2013. The underwent testing (group 1) 3), after which operator examined time motion ultrasound image from test located specific liver portion focused 2). consistency two tests' results was investigated by Pearson's correlation analysis, difference stiffness CHB cirrhosis...
Rationale: Vanishing bile duct syndrome (VBDS) consists of a series diseases characterized by the loss >50% in portal areas. Many factors are associated with VBDS including infections, neoplasms, and drugs. Antibiotic is one most frequently reported causes VBDS. Patient concerns: A 29-year-old female was admitted because liver injury for over 3 months. Tests viruses that can cause hepatitis autoantibodies were all negative. She prescribed antibiotics approximately week before while there no...
As a hepatocellular carcinoma biomarker, serum Golgi protein 73 (GP73) is reportedly related to inflammation. Acute-on-chronic liver failure (ACLF) characterized by severe systemic In this study, we aimed explore the association between GP73 level and short-term mortality in patients with alcohol-associated disease-related ACLF (ALD-ACLF).This retrospective cohort study involved 126 Chinese adults ALD-ACLF. Baseline was measured using enzyme-linked immunosorbent assay. Patients were...
Aim: The potential of long noncoding RNA in hepatocellular carcinoma (HCC) has led to promising insights into therapeutic intervention. clinical significance LINC02518 HCC is unclear. This study aimed evaluate the predictive value a novel RNA, LINC02518, for prognosis patients with HCC. Methods: Between December 2005 and November 2011, 125 75 training validation groups, respectively, who underwent liver surgery were included our study. expression corresponding nontumor tissues was detected...
Hyperandrogenism is a leading cause of developmental retardation in ovarian granulosa cells. Previous studies have indicated that curcumin significantly improves follicular dysplasia, characteristic the polycystic ovary syndrome. In this study, our purpose was to explore signaling pathways which enable protect development hyperandrogen-induced Ovarian cells treated with or without at different dihydrotestosterone (DHT) levels, were screened for cell viability, reactive oxygen species...
Long-chain polyunsaturated fatty acids (LCPUFAs) and the gut microbiota individually exert notable effects on asthma. However, it remains unknown whether LCPUFAs modulate microbial composition. Twenty-four male BALB/c mice were randomly assigned to control (saline), asthma (ovalbumin (OVA)), groups (OVA plus LCPUFAs). The enhanced pause value was observed decrease upon administration of in challenged with methacholine (12.5, 25, 50 g/mL). treatment decreased number eosinophils BALF compared...
Activation of chronic hepatitis B virus (HBV) infection is an important cause acute-on-chronic liver failure (ACLF). However, the effect HBV-ACLF episode on hepatocellular carcinoma (HCC) occurrence remains largely unknown. A total 769 patients and 2114 HBV-related disease (HBV-CLD) diagnosed between August 1998 December 2011 were enrolled in this prospective cohort study. Of HBV-CLD patients, 380 received lifetime antiviral treatment with nucleos(t)ide analogues. Propensity score matching...
Radiofrequency ablation (RFA) is one of the definitive treatment modalities for liver cancer and has been increasingly used in scenario small-sized cancer. It generally believed that RFA minimally invasive associated with a favorable safety profile patients. However, this interventional technique subject to some morbidity high-risk patients, such as those complicating cirrhosis or located at refractory segment.Herein, we report case middle-aged woman who developed acute failure respiratory...
Objective To investigate the factors affecting health-related quality of life (HRQOL) in patients with chronic liver disease (CLD). Methods HRQOL was measured SF-36v2 Chinese version. All CLD diagnosed between December 2009 and May 2011 Liver Research Center, Beijing Friendship Hospital Digestive Department, Chaoyang were enrolled this study. Patients divided into 4 groups according to their Child-Turcotte-Pugh scores: no cirrhosis, Child's classes A, B, C. Demographic clinical data...
Objective To summarize the common types and clinical characteristics of ureter disease;which can increase manipulation difficulties adverse events during rigid ureteroscopic procedures. Methods From Jan 2001 to Dec 2010,our team performed 317 Drocedures for examination or treatment;including 60 difficult procedures(34 male 26 female).The mean age patients was 37 years (range,18 71).The ureteral diseases were classifted into five according pathological characteristics:Type Ⅰ calculous...